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55489 Active Projects
TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
Selective disruption of histone deacetylase complexes using protein interaction modulators
5TfR01ActfCA266194Projectf04YearfDANA-FARBER CANCER INST2025NCI
NCI
$612,114
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Engineering bacterial group I introns for efficient production of safe and durable nucleoside-modified circular mRNA therapeutics
1TfF31ActfGM157877Projectf01YearfUNIV OF MASSACHUSETTS MED SCH WORCESTER2025NIGMS
NIGMS
$33,780
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Simultaneous profiling of neuronal synapse activities, proteins, and messenger RNAs at the single-cell level
2TfR01ActfMH112694Projectf06YearfMASSACHUSETTS INSTITUTE OF TECHNOLOGY2025NIMH
NIMH
$416,750
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Molecular Repair of Diabetic Mesenchymal Stem Cells (dMSC) for Peripheral Arterial Disease
2TfI01ActfBX004707Projectf06YearfVETERANS HEALTH ADMINISTRATION2025VAView View Similar Projects Similar Projectsf
NET stabilization: mechanistic and therapeutic studies studying the role of NETs in thromboinflammatory disease
1TfR00ActfHL177830Projectf01YearfCHILDREN'S HOSP OF PHILADELPHIA2025NHLBI
NHLBI
$445,000
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Contribution of Small Airways to Mucociliary Transport Dysfunction
5TfR01ActfHL167025Projectf03YearfUNIVERSITY OF IOWA2025NHLBI
NHLBI
$660,379
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Modulating Stochastic Gene Expression for Cell-fate Control and Therapeutics
5TfR37ActfAI109593Projectf11YearfAUTONOMOUS THERAPEUTICS, INC.2025NIAID
NIAID
$1,927,847
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Elucidating the molecular changes of the outflow pathway extracellular matrix that regulate outflow facility in steroid-induced ocular hypertension and open angle glaucoma
1TfR01ActfEY036983Projectf01YearfSUNY DOWNSTATE MEDICAL CENTER2025NEI
NEI
$661,635
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Mechanisms of cAMP-dependent regulation of melanosome pH
5TfR01ActfAR077664Projectf05YearfWEILL MEDICAL COLL OF CORNELL UNIV2025NIAMS
NIAMS
$562,467
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Role of SNARE Interactions in Central Synapse Function
5TfR01ActfNS134128Projectf23YearfVANDERBILT UNIVERSITY2025NINDS
NINDS
$397,613
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Enhanced Transretinal Ultrasound Delivery (ETUDe)
1TfF30ActfEY037188Projectf01YearfRICE UNIVERSITY2025NEI
NEI
$53,974
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Improving recovery for marginalized young adults living with serious mental illnesses using music-based self-management strategies: A mixed methods study
1TfF31ActfMH139148Projectf01A1YearfNEW YORK UNIVERSITY2025NIMH
NIMH
$39,806
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Dynamic GABA and Glutamate Neurotransmission in Alzheimer’s Disease and Aging
5TfR01ActfAG070952Projectf03YearfUNIVERSITY OF KENTUCKY2025NIA
NIA
$596,811
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Rational Design of Magnetic Nanoparticles for Cochlear Drug Delivery
5TfK08ActfDC020780Projectf03YearfUNIVERSITY OF CINCINNATI2025NIDCD
NIDCD
$200,506
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GRASP55 Regulates Pancreatic Beta-cell Golgi Structure and Function During Cytokine Stress
5TfF31ActfDK139619Projectf02YearfUNIVERSITY OF IOWA2025NIDDK
NIDDK
$34,138
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Neuroprotective Immunity and HIV Dementia
5TfR01ActfNS034239Projectf30YearfUNIVERSITY OF NEBRASKA MEDICAL CENTER2025NINDS
NINDS
$690,748
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Neutralizing oxidative damage at telomeres prevents T cell dysfunction and improves adoptive cell therapies against cancer
1TfR21ActfCA296693Projectf01YearfUNIVERSITY OF PITTSBURGH AT PITTSBURGH2025NCI
NCI
$222,998
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CD98hc Brain Shuttles for Delivering Off-the-shelf Neuroprotective Antibodies in Alzheimer's Disease
5TfR01ActfAG080016Projectf03YearfUNIVERSITY OF MICHIGAN AT ANN ARBOR2025NIA
NIA
$675,215
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CD98hc Brain Shuttles for Delivering Off-the-shelf Neuroprotective Antibodies in Alzheimer's Disease
3TfR01ActfAG080016Projectf03S1YearfUNIVERSITY OF MICHIGAN AT ANN ARBOR2025NIA
NIA
$94,262
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Molecular mechanisms of ribosome biogenesis by force-producing enzymes
1TfR35ActfGM157075Projectf01YearfRUTGERS BIOMEDICAL AND HEALTH SCIENCES2025NIGMS
NIGMS
$392,500
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Microglia-Vascular Interaction in Alteration of Blood-Retinal Barrier in Diabetic Retinopathy
5TfI01ActfBX005348Projectf04YearfALBUQUERQUE VA MEDICAL CENTER2025VAView View Similar Projects Similar Projectsf
Role of particle surface functionalization in inflammation
5TfR01ActfES033533Projectf04YearfUNIVERSITY OF MONTANA2025NIEHS
NIEHS
$512,929
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Functional mapping of noncoding regulatory variants in human neuronal subtypes3.
5TfR01ActfMH129372Projectf04YearfICAHN SCHOOL OF MEDICINE AT MOUNT SINAI2025NIMH
NIMH
$543,751
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Adrenomedullin 2 Regulates ILC2 Responses to Control Intestinal Inflammation
1TfF32ActfDK139586Projectf01A1YearfWEILL MEDICAL COLL OF CORNELL UNIV2025NIDDK
NIDDK
$75,904
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MicroRNA Control of Dilated Cardiomyopathy
5TfR01ActfHL130840Projectf06YearfSTANFORD UNIVERSITY2025NHLBI
NHLBI
$586,921
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MicroRNA Control of Dilated Cardiomyopathy
3TfR01ActfHL130840Projectf06S1YearfSTANFORD UNIVERSITY2025NHLBI
NHLBI
$98,828
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Breaching CNS barriers: Deciphering the spatiotemporal regulation of immune cell surveillance following blast TBI
1TfIK2ActfBX006530Projectf01YearfWHITE RIVER JUNCTION VA MEDICAL CENTER2025VAView View Similar Projects Similar Projectsf
The role of extracellular vesicles in septic encephalopathy metabolism and immunity
5TfR21ActfNS135088Projectf02YearfCHILDREN'S RESEARCH INSTITUTE2025NINDS
NINDS
$227,500
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Exploring the Molecular Physiology of Atrial Fibrillation
5TfR01ActfHL140934Projectf08YearfCOLUMBIA UNIVERSITY HEALTH SCIENCES2025NHLBI
NHLBI
$695,063
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A novel role for EZH2 in A-to-I RNA editing in prostate cancer
5TfR01ActfCA278832Projectf02YearfNORTHWESTERN UNIVERSITY AT CHICAGO2025NCI
NCI
$589,741
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INTEGRATION OF MECHANICAL AND MOLECULAR CUES DURING DISTAL LUNG DEVELOPMENT
5TfR01ActfHL171056Projectf02YearfMAYO CLINIC ROCHESTER2025NHLBI
NHLBI
$532,264
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Development of a novel, noninvasive, sensitive measure of retinal dysfunction
1TfR21ActfEY036209Projectf01A1YearfUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2025NEI
NEI
$245,733
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Mechanisms of Translation Control in Humans
5TfR35ActfGM148352Projectf03YearfUNIVERSITY OF CALIFORNIA BERKELEY2025NIGMS
NIGMS
$547,489
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Unraveling the cell divergent roles of Glucocorticoid-Induced TNF-R Related Protein (GITR): A new opportunity to treat atherosclerosis using targeted immunotherapy
1TfR01ActfHL171097Projectf01A1YearfMAYO CLINIC ROCHESTER2025NHLBI
NHLBI
$709,869
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Synthetic Lethal Targeting of SETD2 in Renal Cell Carcinoma
5TfR01ActfCA271503Projectf03YearfMAYO CLINIC ROCHESTER2025NCI
NCI
$485,587
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Dietary Regulation of Intestinal Inflammation and Repair
5TfR01ActfDK132244Projectf04YearfWEILL MEDICAL COLL OF CORNELL UNIV2025NIDDK
NIDDK
$613,746
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Molecular signature of parabiosis
5TfR01ActfAG072255Projectf05YearfSTANFORD UNIVERSITY2025NIA
NIA
$424,980
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Developing Pluripotent Stem Cells to Model and Treat Lung Disease
5TfP01ActfHL170952Projectf02YearfBOSTON UNIVERSITY MEDICAL CAMPUS2025NHLBI
NHLBI
$2,565,613
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BLRD Research Career Scientist Award Application
5TfIK6ActfBX006041Projectf04YearfWM S. MIDDLETON MEMORIAL VETERANS HOSP2025VAView View Similar Projects Similar Projectsf
Elucidating the Proteolytic Determinants of Flavivirus Infection
5TfF31ActfAI183737Projectf02YearfUNIVERSITY OF ALABAMA AT BIRMINGHAM2025NIAID
NIAID
$44,292
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BCCMA: Determinants and early detection of metastasis in melanoma for unmet needs of Veterans with mucosal melanomas affecting the head, neck, and other rare types
1TfI01ActfBX006498Projectf01YearfVA NEW JERSEY HEALTH CARE SYSTEM2025VAView View Similar Projects Similar Projectsf
Evaluating the Effectiveness of Mindfulness-Based Therapy for SMI Implemented in a Community Mental Health Setting
1TfR01ActfMH136540Projectf01A1YearfBUTLER HOSPITAL (PROVIDENCE, RI)2025NIMH
NIMH
$768,172
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GRP78 signaling and retinal angiogenesis
5TfR01ActfEY034425Projectf03YearfUNIVERSITY OF TENNESSEE HEALTH SCI CTR2025NEI
NEI
$511,066
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Identifying Disease-Specific Immune Cell Shifts in Chronic Fibrotic Interstitial Lung Diseases with Single-Cell RNA Sequencing
5TfF30ActfHL162459Projectf04YearfYALE UNIVERSITY2025NHLBI
NHLBI
$53,974
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Survival of Neisseria gonorrhoeae after primary human neutrophil challenge
2TfR01ActfAI097312Projectf11A1YearfUNIVERSITY OF VIRGINIA2025NIAID
NIAID
$546,940
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Improving Husbandry and Data Reproducibility Through Automated Health Monitoring in Zebrafish Facilities
5TfR44ActfOD035388Projectf03YearfNEMAMETRIX, INC.2025OD
OD
$1,126,155
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Cellular and Molecular Control of Normal and Disordered Erythropoiesis
5TfR35ActfHL171168Projectf02YearfFEINSTEIN INSTITUTE FOR MEDICAL RESEARCH2025NHLBI
NHLBI
$853,132
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Function of GPCR heteromeric complexes in brain
2TfR01ActfMH084894Projectf15A1YearfVIRGINIA COMMONWEALTH UNIVERSITY2025NIMH
NIMH
$447,909
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The Ethics of Engagement in Patient-Focused Drug Development for Rare Diseases
1TfR01ActfHG014059Projectf01YearfSTANFORD UNIVERSITY2025NHGRI
NHGRI
$605,280
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Genome engineering therapeutics for cystinuria and its metabolic consequences.
5TfI01ActfBX004258Projectf07YearfVETERANS HEALTH ADMINISTRATION2025VAView View Similar Projects Similar Projectsf