Administrative Core Abstract The Center for Multiparametric Imaging of Tumor Immune Microenvironments (C-MITIE) Administrative and Coordination Core (ACC) will facilitate the work of C-MITIE and maximize its impact. The C-MITIE ACC will be led by MPIs Paolo Provenzano and Kevin Eliceiri and RTB PI David Odde. Staff Program Manager Bo Connelly will facilitate the work of the ACC. The ACC will facilitate efficient and effective leadership of this U54 through quarterly Steering Committee meetings, participation in, and support of, annual CCBIR meetings and other network events, and annual External Advisory Panel evaluation of C-MITIE activities. Developing a robust, iterative exchange of technological innovation and biological insight among the research test beds and tech unit will be crucial to the success of this center. Building from the strong foundation of collaboration and friendship among the center leadership, the ACC will develop multiple processes and programs to facilitate this iterative exchange. C-MITIE acknowledges that systemic bias is pervasive in our society and recognizes that proactive action is necessary to cultivate an inclusive center environment diverse in life experience, racial, gender, and cultural backgrounds. In particular, C-MITIE acknowledges that including the perspective of cancer survivors into the C- MITIE environment will yield a richer center experience for all centered on the ultimate goal of improving clinical outcomes for cancer patients. C-MITIE pledges to invest in diversity, equity, and inclusion.