ABSTRACT: ADMINISTRATIVE CORE The Ohio State University Vision Sciences Research Core Program (OSU-VSRCP) is directed by Sayoko Moroi, MD, PhD, Dept of Ophthalmology and Visual Sciences (DOVS). The OSU-VSRCP has established scientific connections and collaborations across five academic units (i.e., College of Medicine (COM), College of Optometry (COO), College of Engineering (COE), College of Veterinary Medicine, College of Arts and Sciences) and newly engaged Nationwide Children’s Hospital (NCH). This community of vision scientists spans basic-translational-clinical research from ophthalmology, optometry, neuroscience, engineering, veterinary ophthalmology, psychology, and pediatrics. Dr. Moroi has commitment from Deans and Chairs to purchase equipment, support data science, assign scarce space, increase collaborations among NEI-funded PIs, and pilot programs for preliminary data. The leadership and vision scientists are aligned with the NEI PAR- 20-051 ‘to enhance the capabilities of participating NEI-funded investigators and the institution for conducting vision research.’ This NEI P30 has three scientific cores: Core A. Structural and Functional Assessments Core (SFA) with an agreement for machine shop services, Core B. Biostatistics, Bioinformatics and Genetic Analysis Core (BBGA), which combines traditional statistics and statistical genetics, and Core C. Image Analysis and Data Science (IADS) Core for the timely need of expertise in artificial intelligence for imaging and large data sources. These Cores were determined from a survey of 61 vision scientists. Each Core has a Director and Co-director, with at least one holding an NEI R01. The synergy among this community has been established with monthly ViSOR (Vision Sciences OSU Research) seminars. Synergy between Cores has been defined by the Steering Committee composed of the PD, Core Directors and Co-directors, who represent DOVS, Dept. Neuroscience, Dept. Biomedical Informatics, Dept. Computer Science (COE), and COO. The synergy between Cores will coincide with monthly ViSOR meetings. In addition, an Advisory Group will provide guidance twice a year to the Steering Committee. The Administrative Core has four aims designed for the successful implementation of our OSU-VSRCP: Aim 1. Policy and oversight; Aim 2. Communication with users; Aim 3. Tracking, reporting and fiscal activities; and Aim 4. Promoting collaboration. This proposed P30 core intends to maximize efficiency, offer centralized access to equipment and expertise that would be difficult, costly or impractical to duplicate in individual labs, and use protocols to ensure best practices to perform science at the highest standard. Credit to Core A Director Fischer and Co-director Cebulla for setting the collaborative culture of equipment sharing to enable initiating OSU-VSRCP. The expected outcome is increased collaboration for successful new proposals with the shared overarching goal to prevent blindness, restore vision and develop cures for eye diseases.