The Administrative Core (ADM) will provide the fundamental infrastructure necessary to strengthen biology of aging research for the members of the Einstein-Nathan Shock Center (E-NSC) at the Albert Einstein College of Medicine, and external members of the E-NSC. Through scientific and administrative leadership, institutional support and the maintenance of cost efficient research Cores, the ADM will continue to promote and nourish excellence in biology of aging research. Efforts will be directed to promote cross-fertilization among investigators of ongoing research projects, to support new collaborative multidisciplinary projects, and to foster the development of investigators new to aging research through evaluations of our research and mentoring initiatives. The ADM manages resources, integrates the scientific research activities of Center members, oversees service activities of Research Resource Cores, ensures regular communications among E-NSC scientists as well as with other NSCs, and manages program enrichment. The heart of the ADM mission is optimization of resources, assurance of quality control, fiscal management and compliance with institutional and NIH policies, through successful conduct of the following specific aims. Aim 1) To provide dynamic leadership and supportive resources to the E-NSC. The Executive Committee will provide strong consistent scientific leadership to foster biology of aging research. The ADM will articulate and implement a clear vision for the scientific Center direction via its Executive and External Advisory committees and maintenance of membership; it will facilitate collaborations as well as institutional advocacy. It will provide fiscal management and compliance with Institutional DHHS, NIH and NIA policies. Aim 2) To manage, supervise, improve E-NSC Cores and other functions. ADM leadership will ensure that the Research Resource Cores are consistently managed and evolve to meet the needs of investigators in aging research and continue the development of cutting edge advanced technology. Aim 3) To manage Program Enrichment. In addition to journal clubs and work-in-progress meetings, we will continue to administer a formal enrichment program covering biology of aging research topics , including monthly seminars, mini-retreats and our graduate course in the Biology of Aging. Aim 4) To expand the use of E-NSC resources and engage in geroscience efforts. a) Attracting leading scientists to engage in aging research through use of E-NSC Research Resources Cores and other Institute of Aging Research resources for biology of aging research. b) Collaborate substantially with other NSCs and the Nathan Shock Centers Coordinating Center (AFAR), and developing conferences and outreach activities, as well as the joint conferences ( in years 2 and 4). )c) Spreading the ‘Gospel’ of Geroscience around the country and the world.