QUALITY OF WELL BEING (QWB) SCALE REVISION PROJECT
Project Number1R01HS009170-01A1
Contact PI/Project LeaderKAPLAN, ROBERT M
Awardee OrganizationUNIVERSITY OF CALIFORNIA, SAN DIEGO
Description
Abstract Text
DESCRIPTION: The specific aims of the proposed project are: to develop and
validate a self-administered form of the QWB, referred to as the QWB-SA; to
perform preference measurement studies in order to obtain a scoring system
for the QWB-SA; and to develop a vision specific scoring system for the
QWB-SA.
Aim 1: Develop and validate QWB-SA. Aim 1 involves several steps. First
the investigators will expand on the current list of symptoms in the QWB. A
draft of the QWB-SA (already developed) will be sent to 15 experts for
review and comment. Next, a content analysis of the HRQL literature will be
performed to determine the degree to which the QWB-SA adequately captures
items included in existing measures. After further revisions of the QWB are
complete, the QWB-SA will be pilot tested at the UCSD Multipurpose Arthritis
Center, and with patients in Family Medicine Clinics. Next, the measure
will be field tested in ongoing studies at UCSD and in clinical research
centers. In addition, a stratified random sample of 10 percent (200) will
be selected for further study. These 200 patients will complete the
interviewer administered QWB and the SF-36, with appropriate
counterbalancing and administration at two time points with about one-month
separation.
A qualitative analysis for assessing the accuracy of information developed
in the surveys will be performed on the 200 patients' data, using the
Internal Consistency Analysis method. Additional analyses of the full
2,000, and the subset of 200, will include: item analysis to assess missing
data rates and frequency distributions for all items; comparisons of mean
QWB and QWB-SA scores; correlation analyses of all components of the QWB,
QWB-SA and SF-36 to determine which of the QWB's is most correlated with the
SF-36; and subanalyses of the QWB-SA by demographic variables, including
age, gender, and education. Profile scoring of the QWB will be performed
using factor analyses, with expected clusters including: physical activity,
social activity, self-care, mobility, pain, emotional functioning, and
sensory functioning. Factor scores will be created by obtaining the sum of
item responses and factor score coefficients separately for each dimension.
Aim 2: Preference measurement study to obtain a scoring system for the
QWB-SA. Five hundred patients from the primary care clinics at the UCSD
will be recruited into this phase of the proposed research. They will be
evenly divided by gender, all will be adults, and about 40 percent will be
African American or Hispanic. All participants will rate complete case
descriptions and components of different health states, using a 1-100 point
scale. Analyses of the preference data will involve two phases:
establishment of the interval scale property and the development of the
model of judgment; and, estimation of value weights.
Aim 3: Disease-specific versus general measure. In this phase of the
study, the investigators propose to develop a vision specific scoring system
for the QWB-SA. Two hundred fifty patients undergoing their first eye
cataract extraction will be recruited into the study. Participants must be
older than 35 years of age. Exclusion criteria include: inability to speak
English; serious hearing impairment; cognitive impairment; patients
undergoing simultaneous glaucoma, corneal or vitro-retinal procedures;
patients with traumatic cataracts; and patients with visual impairment so
severe that they cannot complete a self-administered form. In addition to
the QWB-SA data, data will be collected on visual acuity and patients will
complete the VF-14, a functional status measure designed specifically for
visual problems. Also, a cataract symptom score scale and a brief medical
co-morbidity scale will be administered to the patients. Psychometric
methods will be used to evaluate items from the QWB-SA and the
vision-specific measures in relation to visual acuity and a vision specific
outcome measure.
Public Health Relevance Statement
Data not available.
NIH Spending Category
No NIH Spending Category available.
Project Terms
behavioral /social science research tagcataract surgeryclinical researcheye prosthesishealth care cost /financinghealth care policyhealth care service evaluationhealth services research taghuman subjectoutcomes researchpreferencequality of lifequestionnairesvision disorders
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