MED CORD CENTER FOR VIRAL ACTIVATION TRANSFUSION STUDY
Project NumberN01HB057127-001
Contact PI/Project LeaderKALISH, LESLIE
Awardee OrganizationNEW ENGLAND RESEARCH INSTITUTES, INC.
Description
Abstract Text
The contractor shall serve as the Medical Coordinating Center for the
Viral Activation Transfusion Study. This study is designed to determine
if transfusion is followed by activation of HIV-1 and Cytomegalovirus
(CMV) in HIV-1 infected persons and thereby adversely affects prognosis.
It will also evaluate the role of donor leukocytes producing this
activation by examining the effect of removing leukocytes by filtration or
abolishing their ability to proliferate by gamma irradiation. Finally,
the study will examine the persistence of donor lymphocytes after
transfusion.
No Sub Projects information available for N01HB057127-001
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