DOES EXERCISE IMPROVE LOCOMOTION IN DISABLED ELDERS?
Project Number5R01AG012561-04
Contact PI/Project LeaderKREBS, DAVID E
Awardee OrganizationMASSACHUSETTS GENERAL HOSPITAL
Description
Abstract Text
DESCRIPTION (Adapted from the Applicant's Abstract): Little is known
about the functional benefits of strengthening exercises in older
persons. The proposed project will experimentally determine if
strengthening exercises for community-dwelling, disabled older men and
women result in improvements in gait and other locomotor activities. The
experimental plan proposes to study 100 disabled elders randomly
assigned to 6 months strengthening exercises or no-exercise control.
The general hypothesis is that disabled older persons compensate for
strength impairments by substituting potentially destabilizing,
quantifiable body postures and movement strategies, and that these
compensations are reduced following strength gains. Proposed Specific
Aims are: 1) to determine the body segment postures, momentum and
compensatory strategies in disabled older persons. It is hypothesized
that disabled older persons use excessive upper body momentum to
substitute for lower limb weakness during locomotor activities; 2) to
assess whether functional abilities improve following a 6 month lower
limb strengthening program. It is speculated that following 6 months
of strengthening exercise, subjects move about more rapidly and with
greater stability than subjects in the control group, and that change
in strength correlates (r>.8) directly with change in locomotor velocity
and torques, and inversely with use of segmental momentum transfer
during locomotor activities; and 3) to ascertain whether improvement in
functional ability results in a change in disability. It is proposed that
changes in functional abilities identified under Aim #2 will, in turn,
result in improvements in disability during real life role activities.
Public Health Relevance Statement
Data not available.
NIH Spending Category
No NIH Spending Category available.
Project Terms
exercisefunctional abilitygaithuman old age (65+)human subjectperson with disabilityposturequality of life
No Sub Projects information available for 5R01AG012561-04
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