DATA RESOURCE FOR ANALYZING BLOOD AND MARROW TRANSPLANTS
Project Number5U24CA076518-02
Former Number1P01CA076518-01
Contact PI/Project LeaderHOROWITZ, MARY MARESCA
Awardee OrganizationMEDICAL COLLEGE OF WISCONSIN
Description
Abstract Text
The Statistical Center of the International Bone Marrow Transplant
Registry (IBMTR) and the Autologous Blood and Marrow Transplant Registry
of North America (ABMTR) coordinates an international effort to collect
and analyze data on outcome of blood and bone marrow (hematopoietic stem
cell) transplants. The IBMTR, established in 1972, and the ABMTR,
established in 1990, involve greater than 400 transplant centers in 47
countries. Participating centers submit data on consecutive transplants
to the IBMTR/ABMTR Statistical Center. The Registries have data for
greater than 65,000 transplants. These data are used for determining
transplant results in specific clinical situations, identifying
prognostic factors, comparing transplant regimens, comparing transplant
with non-transplant therapy, assessing intercenter variability in
diagnosis, practice and outcome, evaluating transplant costs and cost-
effectiveness, planning clinical trials or treatment protocols, and
developing approaches to evaluating transplant outcome. Statistical
Center personnel have a strong record of expert and innovative analyses
of these and other issues using IBMTR/ABMTR data. The proposed grant
will support continued development of this unique resource of data and
statistical expertise. The proposal outlines several enhancements to
the Statistical Center's data collection, entry and management system,
including addition of cost information, that will ensure availability
of demographic, medical and financial data on a large and representative
group of transplant recipients for use by the scientific community. The
proposal includes several strategies to increase awareness of this
resource and enhance its availability to investigators and health policy
makers, including development of a public use database. The project will
also develop statistical methodologies appropriate for unbiased and
efficient analyses of transplant data and provide expert statistical
support for studies using IBMTR/ABMTR data.
Public Health Relevance Statement
Data not available.
NIH Spending Category
No NIH Spending Category available.
Project Terms
autologous transplantationblood transfusionbone marrow transplantationcomputer program /softwaredata collection methodology /evaluationhealth care cost /financinghealth care facility information systemhealth services research taghematopoietic stem cellshomologous transplantationhuman dataoutcomes researchpatient /disease registrystatistical service /centerstatistics /biometry
National Institute of Allergy and Infectious Diseases
$430,372
1999
National Cancer Institute
$1,727,601
1999
National Heart Lung and Blood Institute
$200,000
Year
Funding IC
FY Total Cost by IC
Sub Projects
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Publications
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