Our objective is to determine the three-dimensional structure of bacterial
luciferase by the method of X-ray crystallography. Recent success in
obtaining large crystals of the protein makes this a feasible undertaking.
This will be the first known structure of any bioluminescent system and
will be a major step toward understanding the phenomenon of light emission.
The study will also contribute to our understanding of the structure and
function of biological systems in general and flavin-proteins in particular.
Public Health Relevance Statement
Data not available.
NIH Spending Category
No NIH Spending Category available.
Project Terms
VibrioX ray crystallographyelectron densityenzyme structureluciferin monooxygenasephotochemistry
No Sub Projects information available for 5R01GM035114-03
Publications
Publications are associated with projects, but cannot be identified with any particular year of the project or fiscal year of funding. This is due to the continuous and cumulative nature of knowledge generation across the life of a project and the sometimes long and variable publishing timeline. Similarly, for multi-component projects, publications are associated with the parent core project and not with individual sub-projects.
No Publications available for 5R01GM035114-03
Patents
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No Outcomes available for 5R01GM035114-03
Clinical Studies
No Clinical Studies information available for 5R01GM035114-03
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History
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Similar Projects
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