Our objective is to determine the three-dimensional structure of bacterial
luciferase by the method of X-ray crystallography. Recent success in
obtaining large crystals of the protein makes this a feasible undertaking.
This will be the first known structure of any bioluminescent system and
will be a major step toward understanding the phenomenon of light emission.
The study will also contribute to our understanding of the structure and
function of biological systems in general and flavin-proteins in particular.
Public Health Relevance Statement
Data not available.
NIH Spending Category
No NIH Spending Category available.
Project Terms
VibrioX ray crystallographyelectron densityenzyme mechanismenzyme structureluciferin monooxygenasephotochemistry
No Sub Projects information available for 5R01GM035114-05
Publications
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No Outcomes available for 5R01GM035114-05
Clinical Studies
No Clinical Studies information available for 5R01GM035114-05
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History
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Similar Projects
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