DIET MODIFICATION AND BLOOD PRESSURE IN YOUNG PEOPLE
Project Number5R01HL032821-03
Contact PI/Project LeaderELLISON, R. CURTIS
Awardee OrganizationUNIV OF MASSACHUSETTS MED SCH WORCESTER
Description
Abstract Text
In an attempt to ascertain the effects on blood pressure of variations in
the dietary intake of sodium and linoleic acid, food preparation will be
modified at two boarding high schools in New England over four school
years. During the first year, dining hall food at one school will be
prepared with 50% less sodium; the total intake of sodium by students
(dining hall food, outside food, snacks) should be reduced by approximately
35%, to an average level of 75-90 mEq (less that 5 grams of salt) per day.
The other school will serve as a control, continuing to prepare food with
usual amounts of sodium. During the second year, the intervention will
take place at the second school, wh le the other serves as a control.
During the third and fouth years, sodium intake will be kept at usual
levels while changes are made in food preparation alternately at each
school to bring about a doubling in the polyunsaturated fatty acid intake
of students (from 4% to 8% of dietary calories). Repeated food diaries,
duplicate food samples and 24 hour urine collections by approximately 200
students at each school (those taking the basic course in Biology) will be
utilized to monitor the dietary modifications and student compliance with
the prescribed changes.
The effects of these dietary changes on blood pressure will be monitored
with weekly blood pressure masurements by the 200 students taking Biology
at each school. An automatic blood pressure apparatus which has been found
to give reliable measurements in this setting will be utilized. The
effects of the dietary interventions on blood pressure will be estimated
from differences in blood pressure between the schools (intervention and
control). Among factors which will be evaluated as potential modifiers of
the effect are age, gender, baseline blood pressure level, family history
of hypertension, ponderosity and the degree of compliance with the dietary
change.
Previous studies at these school have shown a high degree of enthusiasm and
compliance by participating students. Furthermore, such work has
demonstrated that the desired level of dietary change can be readily
achieved. Thus, the proposed study offers the opportunity to determine the
frequency with which young persons will lower their blood pressure given
such modifications in sodium and linoleic acid intake, and the magnitude of
such changes. It should provide valuable information regarding results
that could be expected if the current dietary recommendations of the U.S.
government are applied to populations of "normal" young people.
Public Health Relevance Statement
Data not available.
NIH Spending Category
No NIH Spending Category available.
Project Terms
adolescence (12-20)diet therapydietary lipiddietary mineralhuman subjecthypertensionlinoleatenutrition related tagsecondary schoolssodiumtherapy complianceurinalysis
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