DESCRIPTION (Adapted from Investigator's Abstract): This is an application
for continuation of an existing study of the early, mid, and late-life
factors contributing to the onset and course of Alzheimer's disease (AD).
This research uses archival longitudinal data from a volunteer sample of
N=678 Catholic Nuns, aged 75 to 103 (in 1991). The investigators seek to
continue the evaluation of this cohort for risk factors for Alzheimer's
disease (AD) until the year 2001. The proposal seeks to substantiate
preliminary findings that AD is not an inevitable consequence of biologic
aging and that AD is related to early life factors, and analyzes the effects
of genetic markers and other, later risk factors for AD.
Public Health Relevance Statement
Data not available.
NIH Spending Category
No NIH Spending Category available.
Project Terms
Alzheimer's diseaseagingapolipoproteinscerebral cortexclinical researchdisease /disorder onsetdisease /disorder proneness /riskearly experienceeducationfunctional abilitygenetic markershead /neck injuryhippocampushuman old age (65+)human subjecthuman very old age (85+)languagelifestylelongitudinal human studymemoryneuritic plaquesneurofibrillary tanglesneuronsprognosisself caresynapsesvitamin B deficiency
No Sub Projects information available for 5R01AG009862-10
Publications
Publications are associated with projects, but cannot be identified with any particular year of the project or fiscal year of funding. This is due to the continuous and cumulative nature of knowledge generation across the life of a project and the sometimes long and variable publishing timeline. Similarly, for multi-component projects, publications are associated with the parent core project and not with individual sub-projects.
No Publications available for 5R01AG009862-10
Patents
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Outcomes
The Project Outcomes shown here are displayed verbatim as submitted by the Principal Investigator (PI) for this award. Any opinions, findings, and conclusions or recommendations expressed are those of the PI and do not necessarily reflect the views of the National Institutes of Health. NIH has not endorsed the content below.
No Outcomes available for 5R01AG009862-10
Clinical Studies
No Clinical Studies information available for 5R01AG009862-10
News and More
Related News Releases
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History
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Similar Projects
No Similar Projects information available for 5R01AG009862-10