Awardee OrganizationUNIVERSITY OF MICHIGAN AT ANN ARBOR
Description
Abstract Text
The project involves genetic linkage of retinoschisis pedigrees, toward
the end of positional cloning of the gene responsible for this human
disease. Retinoschisis causes impaired central and peripheral vision
and is a leading cause of juvenile macular degeneration. Thus far, the
work has narrowed the genetic interval for the RS locus, from a previous
10 cM, to 3.4 cM, and now to 0.9 cM. This region is contained in 3
YACs, and we are searching for expressed sequences as candidate genes
for retinoschisis.
No Sub Projects information available for 5M01RR000042-37 0998
Publications
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