Awardee OrganizationCHILDREN'S HOSP OF PHILADELPHIA
Description
Abstract Text
This study is a short-term trial of a new formulation of a long acting
growth hormone (hGH) to evaluate its safety and efficacy. The treatment of
growth hormone deficiency (GHD) since the late 1960's initially with
cadaveric hGH and then, subsequently, with recombinant hGH, has not
changed in terms of method of administration of the hormone. The children
were treated with frequent injections of hGH. Initially, this was three
times per week intramuscularly and present standard treatment is daily
subcutaeous injections of hGH. The present drug to be tested is a
commercial growth hormone combined into a polyacrimide substance presently
used as a dissolvable suture material to provide, theoretically, a slow
release long acting hGH. This study is intended to evaluate possible side
effects and short term efficacy. Future plans include a long term study
of this drug to evaluate efficacy.
No Sub Projects information available for 3M01RR000240-34 0474
Publications
Publications are associated with projects, but cannot be identified with any particular year of the project or fiscal year of funding. This is due to the continuous and cumulative nature of knowledge generation across the life of a project and the sometimes long and variable publishing timeline. Similarly, for multi-component projects, publications are associated with the parent core project and not with individual sub-projects.
No Publications available for 3M01RR000240-34 0474
Patents
No Patents information available for 3M01RR000240-34 0474
Outcomes
The Project Outcomes shown here are displayed verbatim as submitted by the Principal Investigator (PI) for this award. Any opinions, findings, and conclusions or recommendations expressed are those of the PI and do not necessarily reflect the views of the National Institutes of Health. NIH has not endorsed the content below.
No Outcomes available for 3M01RR000240-34 0474
Clinical Studies
No Clinical Studies information available for 3M01RR000240-34 0474
News and More
Related News Releases
No news release information available for 3M01RR000240-34 0474
History
No Historical information available for 3M01RR000240-34 0474
Similar Projects
No Similar Projects information available for 3M01RR000240-34 0474