APEX: ADIPOSITY PREVENTION BY EXERCISE IN BLACK GIRLS
Project Number3R01HL064972-01S1
Former Number1U01HL062665-01A1
Contact PI/Project LeaderGUTIN, BERNARD
Awardee OrganizationAUGUSTA UNIVERSITY
Description
Abstract Text
DESCRIPTION: (Adapted from Investigator's Abstract) The long term objective of
this research is to reduce the epidemic of child obesity that is afflicting
U.S. society. Obese children who engage in vigorous exercise programs show
beneficial effects on total body percent fat (percent BF) and visceral adipose
tissue (VAT); however, little is known about how to prevent accretion of total
body or visceral adiposity in high risk youths, such as African-American (AA)
females. The primary aim is to test the hypothesis that a one year afternoon
exercise program will reduce accretion of general and visceral adiposity in AA
girls. The design will involve randomization of AA girls, eight to 10 years of
age (n=200) into intervention or control groups. After one year, the groups
will be compared to test the primary hypothesis. Then the girls will switch
group assignments for the next year. The pattern of data over the three time
points will show what happens over a two year period in which the youths are,
or are not, involved in the exercise program. The measurements will include:
(1) percent BF with dual-energy x-ray absorptiometry; (2) VAT with magnetic
resonance imaging; (3) CV fitness with a multi-stage treadmill test; (4) CVD
risk factors (i.e., the ratio of total to high density lipoprotein cholesterol,
insulin, systolic blood pressure, and fibrinogen); (5) free-living exercise and
diet; (6) psychosocial variables (i.e., self-efficacy and self-concept); C7)
sexual maturation; (8) anthropometric measures. The exercise program will be
implemented in neighborhood schools for 90 minutes each weekday afternoon.
Transportation will be provided if needed. Sessions will include motor skill
instruction and aerobic exercises. The investigators state that this project
has important health implications for two reasons, as follow. (1) They state
that there is a dearth of information concerning the effects of exercise
interventions in school and community settings. (2) They further state that if
this project shows that an afternoon exercise program reduces accretion of
general and visceral adiposity and has a favorable impact on fitness and health
in a population that is at high risk of obesity, then schools may be encouraged
to implement similar interventions to prevent juvenile obesity and associated
health problems.
Public Health Relevance Statement
Data not available.
NIH Spending Category
No NIH Spending Category available.
Project Terms
African Americanaerobic exercisebehavioral /social science research tagbody compositioncardiovascular functionclinical researchdietdisease /disorder prevention /controlelementary schoolfemalehealth behaviorhuman pubertyhuman subjecthuman therapy evaluationlongitudinal human studymiddle childhood (6-11)nutrition related tagobesityphysical fitnessself concept
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