The preliminary finding of an association of group B streptococcus (GBS) colonization, beta-lactam use during labor and respiratory distress in newborns will be validated in a prospective adequately powered study. The goals of the study are 1) to relate levels of serum bacterial phospholipids to the occurrence of respiratory distress in newborns of mothers colonized by GBS; and 2) to evaluate the effects of beta-lactam use during labor on the release of bacterial phospholipids and thus, the occurrence of respiratory distress in newborns of mothers colonized with GBS. This study will also examine the pathologic effects of ¿asymptomatic¿ GBS colonization and potential adverse effects of beta-lactam use during labor on the newborns. In addition, other potential adverse events or morbidities in mothers and newborns associated with the use of intrapartum antibiotics will be evaluated.
Public Health Relevance Statement
Data not available.
NIH Spending Category
No NIH Spending Category available.
Project Terms
No Project Terms available.
Details
Other PIs
Not Applicable
Program Official
Name
Contact
Email not available
Organization
Name
City
Country
UNITED STATES
Department Type
Unavailable
Organization Type
Unavailable
State Code
Congressional District
Other Information
Opportunity Number
Study Section
Fiscal Year
2007
Award Notice Date
Administering Institutes or Centers
Eunice Kennedy Shriver National Institute of Child Health and Human Development
CFDA Code
DUNS Number
UEI
Project Start Date
28-September-2007
Project End Date
31-March-2009
Budget Start Date
Budget End Date
Project Funding Information for 2007
Total Funding
$549,396
Direct Costs
Indirect Costs
Year
Funding IC
FY Total Cost by IC
2007
Eunice Kennedy Shriver National Institute of Child Health and Human Development
$549,396
Year
Funding IC
FY Total Cost by IC
Sub Projects
No Sub Projects information available for 267200700009C-2-0-1
Publications
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No Outcomes available for 267200700009C-2-0-1
Clinical Studies
No Clinical Studies information available for 267200700009C-2-0-1
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