This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This subproject should be considered a subset of 0024: Multimodal spectroscopy probe development. All future probes will have the ability to collect Raman, fluorescence, and reflectance spectra.