This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To oversee all research, services, infrastructure, planning and growth, facilities and communications for the Wisconsin National Primate Research Center, toward the goal of studying nonhuman primates to improve human and nonhuman primate health and quality of life. A notable accomplishment in the Director's Office has been the highly efficient teamwork and well honed institutional knowledge of its small but dedicated core staff. Dr. Joseph Kemnitz, who has enjoyed a long and productive research career at the Wisconsin National Primate Research Center since 1976, has been its director since August 1996. Edi Chan, executive assistant to the director, who coordinates all conferences, retreats, seminars, numerous reports, scientific visits and other activities hosted by the Director's Office, has served for 26 years. Jordana Lenon, public information officer, has served 11 years. One significant highlight during this reporting period was the successful renewal of our base operating grant after a challenging period of operating under reduced bridge funding. The University of Wisconsin-Madison won a Clinical and Translational Science Award (CTSA) in September 2007. The WNPRC is well integrated into this enterprise and this award is another major highlight of the current reporting period. Dr. Kemnitz is supervisor of the Translational Technologies Resource Core (which includes the Assay Services and Pathology Services units at the WNPRC) and serves on the Management Committee and Informatics Committee. There were frequent meetings during this reporting period in which Dr. Kemnitz participated to prepare for and then implement the CTSA. He also participated in the first meeting of the External Advisory Committee for the CTSA in February 2008. We hosted visits by Dr. Yue Feng (Wincon Thera Cell, Nanning, China), Dr. Jeff Grethe (BIRN, UC, San Diego), Dr. Barbara Hansen (University of South Florida), Mr. Ken Kubota, Kinetics Foundation, Sunnyvale, CA), Dr. Jeff Rogers (SWNPRC) during this reporting period, as well as a 28-member delegation to review our base grant renewal application. Internally, the Director's Office hosted two general staff meetings in during this reporting period, several scientific seminars, quarterly scientific research retreats, monthly Executive Committee meetings, monthly Internal Action Committee meetings, multiple New Employee Orientation sessions, and the annual meeting with the Chancellor and Deans. Division and Unit heads met with the director on a frequent basis during the year, as we prepared our competing renewal application for the base operating grant and prepared for the site visit in January 2008. Locally, the Director chaired the Expert Review Committee meeting for the UW-Madison Center for Women's Health Research in February 2008. He also participated in several campus meeting for center directors and department chairs. The director participated in the following meetings off site during the current period: -- Meeting of the Animal Care and Experimentation Committee, American Physiological Society, Washington, DC, May 2007 -- Meeting of the Federation of American Societies for Experimental Biology, Washington, DC, May 2007. -- NCRR Informatics Meeting, Bethesda, MD, May 2007 -- NPRC Directors meeting, Bethesda, MD, May 2007 -- American Diabetes Association meeting, Chicago, IL, June 2007 -- Institute of Laboratory Animal Research (ILAR), Council meeting, Woods Hole, MA, July 2007 -- Meeting with NHP Programs staff, NCRR, August 2007 -- NPRC Directors meeting, Monterrey, CA, September 2007 -- BIRN "All Hands" Meeting, Bethesda, MD, October 2007 -- NIA Special Review Committee meeting, Bethesda, MD, November 2007 -- ILAR Council meeting, Washington , DC, November 2007 -- Informatics meeting, NCRR, Bethesda, MD, January 2008 -- CTSA Translational Technologies Resource Core meeting, NCRR, Bethesda, MD, January 2008 -- NCRR Council meeting, Bethesda, MD, January 2008 -- ILAR Council meeting, Irvine, CA, March 2008 -- NHP Genomics meeting, Seattle, WA, April 2008 -- NPRC Directors meeting, April 2008 The Primate Center's general progress is readily available to a variety of audiences via printed and electronic materials produced by the Public Information Office. Most of these materialspress releases, newsletter articles, a brochure, and fact sheetsappear at www.primate.wisc.edu. The PIO also produced outreach bookmarks and posters during this reporting period. Local, national and international scientific media interest in WNPRC activities remained high in 2007-2008, with weekly scientific media queries and near monthly visits by science journalists and documentary crews. The P01 caloric restriction and aging study continued to generate several science news stories during this reporting period. Other topics garnering science news media coverage and citing the Wisconsin National Primate Research Center included AIDS, Parkinson's disease, nutrition, neurobiology, and embryonic stem cell research. Animal rights related press coverage about the Primate Center was limited to sporadic local coverage and there were no organized protests. The public information officer gave numerous talks for schools and community groups within Wisconsin on primate research and animal care. The PIO is an active presenter and speaker coordinator through the Chancellor's Speakers Bureau, UW-Madison Science Alliance, Stem Cell & Regenerative Medicine Center, and the Center's own in-house outreach program. The PIO relies heavily on Center staff, especially Director's Office and Animal Services staff, to assist her with outreach activities. The biggest challenge facing the PIO during this reporting period was trying to complete traditional job duties while serving only a 60% appointment. The good news was that the remaining 30% of the PIO's current 90% appointment was picked up by the new Stem Cell and Regenerative Medicine Center, and also through a new Ira and Ineva Baldwin Reilly Wisconsin Idea Endowment she received along with PI's Tim Kamp, Clive Svendsen and outreach partner Tom Zinnen at the Biotechnology Center. The PIO is the working leader on this grant, awarded January 2008 and intended to fund a public stem cell learning lab at the Biotechnology Center. The PIO hired a senior majoring in biochemistry and genetics to assist her with this project. The two are working closely with the Thomson Lab and WiCell on this project. The PIO also became certified in Biosafety Training during this reporting period.