DEVELOPMENT OF MEDICAL COUNTERMEASURES TO MITIGATE AND/OR TREAT RADIATION-INDUCED LUNG INJURY AFTER A RADIOLOGICAL/NUCLEAR INCIDENT
Project Number272201500005C-2-0-1
Contact PI/Project LeaderHARRIS, JIM
Awardee OrganizationLIGNAMED, LLC
Description
Abstract Text
This contract will support research to accelerate the development of safe and effective medical products to mitigate and/or treat pulmonary injury arising from exposure to ionizing radiation from a radiological or nuclear incident, thereby leading to a reduction in lung-associated morbidities that can impact survival. Currently, there are no approved therapeutic products in the Strategic National Stockpile (SNS) to be used specifically for radiation-induced pulmonary injury.
Public Health Relevance Statement
Data not available.
NIH Spending Category
BiodefenseLung
Project Terms
Animal ModelAnimalsChestClinicalContractsDevelopmentDrug KineticsExposure toGoalsHourInflammatoryInjuryIonizing radiationLungMedicalMorbidity - disease rateNuclearPharmacodynamicsPre-Clinical ModelPreclinical TestingProcessPropertyRadiationResearch SupportStructure of parenchyma of lungTherapeuticTissuesin vivolung injury
OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEALTH
$2,101,929
Lung
Sub Projects
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Publications
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