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2,734 Projects
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Fiscal Year: Active ProjectsFunding Mechanism: SBIR/STTR
TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
Mobile Three-Dimensional Screening for Cranial Malformations
3TfR44ActfDE031461Projectf03S2YearfPEDIAMETRIX INC.2024NIDCR
NIDCR
$50,000
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Mobile Three-Dimensional Screening for Cranial Malformations
5TfR44ActfDE031461Projectf03YearfPEDIAMETRIX INC.2024NIDCR
NIDCR
$858,535
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Mobile Three-Dimensional Screening for Cranial Malformations
3TfR44ActfDE031461Projectf03S1YearfPEDIAMETRIX INC.2024NIDCR
NIDCR
$44,553
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Vitiligo topical treatment applying a potent, highly selective MC1R agonist
1TfR41ActfAR083311Projectf01YearfMC1R VENTURES LLC2023NIAMS
NIAMS
$295,913
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Development of a Totally Implanted Left Ventricular Assist Device
1TfR44ActfHL177945Projectf01YearfCORVION, INC.2025NHLBI
NHLBI
$1,024,635
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Comparison of convection enhanced delivery systems in a randomized controlled clinical study of recurrent Grade 3-4 glioma patients
1TfR44ActfCA295197Projectf01YearfCREOSALUS, INC.2024NCI
NCI
$857,315
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Phase 1 Safety, Pharmacokinetic study followed by Phase 2a Proof-of-Concept study of AVR-48, a small molecule macrophage modulator to prevent bronchopulmonary dysplasia in neonates
1TfR44ActfHD112276Projectf01A1YearfAYUVIS RESEARCH, INC.2024NICHD
NICHD
$895,365
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Optimized Ratiometric Voltage-Sensitive Dyes for Cardiac Research, Safety Pharmacology
5TfR44ActfGM152985Projectf02YearfPOTENTIOMETRIC PROBES, LLC2024NIGMS
NIGMS
$929,918
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Morquio A therapy integrating gene transfer with lectin-enhanced enzyme delivery to treat multisystemic clinical impairments of rare metabolic childhood diseases
1TfR43ActfHD114328Projectf01YearfBIOSTRATEGIES, LC2023NICHD
NICHD
$295,923
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Personalized multi-medication packaging with integrated real-time instrumentation to improve adherence
2TfR44ActfTR003071Projectf02A1YearfINSIGHTFIL2024NCATS
NCATS
$677,228
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Ceraxa (Ceramide NanoLiposome) and Vinblastine For the Improved Treatment of Relapsed or Refractory Acute Myeloid Leukemia
5TfR44ActfCA275609Projectf02YearfKEYSTONE NANO, INC.2023NCI
NCI
$999,628
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Disseminable Evidence-Based Treatment for the Dental Office: Virtual Exposure Tools for Dental Fear - neVR Fear the Dentist
5TfR42ActfDE030040Projectf04YearfVIRTUALLY BETTER, INC.2024NIDCR
NIDCR
$412,775
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Clutter-GO: Facilitating Delivery and Adherence in Evidence-Based Treatment for Hoarding Disorder via a Patient-Provider Digital Health Tool
1TfR41ActfMH138146Projectf01YearfVIRTUALLY BETTER, INC.2024NIMH
NIMH
$386,266
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Sustained cysteamine delivery by nanobarrier contact lenses to replace 8xdaily drops with a daily disposable lens
1TfR43ActfEY036347Projectf01YearfDIOPTER TECHNOLOGIES, INC.2024NEI
NEI
$332,179
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Amelioration of opioid use disorder with heterodyned whole body vibration
1TfR42ActfDA060644Projectf01YearfPHOTOPHARMICS, INC.2024NIDA
NIDA
$319,278
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Small molecule targeting an epigenetic regulator for the treatment of osteoarthritis
5TfU44ActfAG074108Projectf04YearfDORIAN THERAPEUTICS, INC.2024NIA
NIA
$1,235,850
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A scalable intervention for stress management practices
1TfR41ActfAT012854Projectf01YearfLIVOTION LLC2024NCCIH
NCCIH
$294,312
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Screening ADNI patient cohorts to identify a sub-population that are AD early progressors in validating the prognostic ability of the Alzosure Predict blood test, 6 years in advance of current methods
5TfR44ActfAG078051Projectf02YearfDIADEM US, INC.2023NIA
NIA
$859,175
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A Framework for mHealth App Security and Privacy Analysis
5TfR42ActfLM014356Projectf03YearfUBITRIX INTERNATIONAL, INC.2024NLM
NLM
$917,997
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mVOR: An mHealth Approach to the Clinical Assessment of Gaze Stability and Telerehabilitation of Vestibular Dysfunction
1TfR41ActfDC022209Projectf01YearfUBITRIX INTERNATIONAL, INC.2024NIDCD
NIDCD
$305,788
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The Development and Systematic Evaluation of an AI-Assisted Just-in-Time-Adaptive-Intervention for Improving Child Mental Health
5TfR44ActfMH123368Projectf05YearfCOLLIGA APPS CORP.2024NIMH
NIMH
$844,605
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The Development and Systematic Evaluation of an AI-Assisted Just-in-Time-Adaptive-Intervention for Improving Child Mental Health
3TfR44ActfMH123368Projectf05S1YearfCOLLIGA APPS CORP.2024NIMH
NIMH
$58,623
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Novel Strategies to Clear Bacteria from the CF Lung
5TfR44ActfHL165964Projectf02YearfELDEC PHARMACEUTICALS, INC.2023NHLBI
NCATS
$977,764
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Novel Peptide Immunomodulators for Treating Sepsis
1TfR43ActfAI174395Projectf01YearfELDEC PHARMACEUTICALS, INC.2023NIAID
NIAID
$259,121
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Targeting galectin-3 to overcome insulin resistance in type 2 diabetes
5TfR44ActfDK125126Projectf03YearfGLYCOMANTRA, INC.2024NIDDK
NIDDK
$1,864,171
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Targeting galectin-3 to intervene COVID-19
5TfR43ActfAI162182Projectf02YearfGLYCOMANTRA, INC.2023NIAID
NIAID
$296,637
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Ethnically Diverse iPSC-Cardiomyocyte Panel for Pharmacogenomics and Drug Safety Testing
5TfR44ActfHL170756Projectf02YearfGREENSTONE BIOSCIENCES, INC.2024NHLBI
NHLBI
$1,447,258
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Late Stage Development of Sustained-release Relaxin for Treating Joint Contracture
1TfSB1ActfAR084380Projectf01A1YearfORTHOLEVO, INC.2024NIAMS
NIAMS
$504,965
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PAH-on-a-chip: a novel disease-on-a-device model for studying the pathobiology of and screening drugs for pulmonary arterial hypertension
5TfR43ActfHL169134Projectf02YearfMEDLUIDICS LLC2024NHLBI
NHLBI
$193,130
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Optimization and Validation of Minimally-Invasive and Low-Cost Blood Collection Device for Lead Testing
1TfR41ActfES036480Projectf01YearfSKYWAY BIOSCIENCES2024NIEHS
NIEHS
$295,923
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Hormone-Free Prebiotic Muco-Adhesive Gels To Treat Vaginal Atrophy in Post-Menopausal Women
6TfR43ActfAG084468Projectf02YearfMOREMME-JAVORE LLC2024NIA
NIA
$67,079
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Targeted delivery of novel miRNA-based therapeutics for pneumonia-induced acute lung injury
5TfR41ActfAI155327Projectf02YearfADVAC THERAPEUTIC, LLC2023NIAID
NIAID
$286,226
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Comprehensive validation and commercial readiness of SpliceIO, a software platform for neoantigen discovery using RNA-seq data
3TfR44ActfCA265446Projectf02S1YearfENVISAGENICS, INC.2023NCI
NCI
$77,000
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Comprehensive validation and commercial readiness of SpliceIO, a software platform for neoantigen discovery using RNA-seq data
5TfR44ActfCA265446Projectf02YearfENVISAGENICS, INC.2023NCI
NCI
$980,257
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Validation of a novel treatment for glioblastoma using oncolytic Zika virus
1TfR44ActfNS137868Projectf01YearfUP ONCOLYTICS, INC.2024NINDS
NINDS
$500,000
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Endoscopy-assisted intracochlear access via ultrasharp-microneedles
1TfR41ActfDC021128Projectf01YearfHAYSTACK MEDICAL, INC.2023NIDCD
NIDCD
$350,033
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System on Chip for Intraoperative OCT
1TfR43ActfEY035946Projectf01YearfMYRIAD ADVANCED TECHNOLOGIES LLC2024NEI
NEI
$269,472
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Metabolism and Mitochondrial Energetics Therapy for Septic Shock
1TfR42ActfGM151928Projectf01A1YearfMEDOSOME BIOTEC, LLC2024NIGMS
NIGMS
$350,000
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A Paper-Based Synthetic Biology Platform for the On-Demand Testing of Water Quality
5TfR44ActfES031899Projectf03YearfSTEMLOOP, INC.2023NIEHS
NIEHS
$953,937
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Dual Fatty Acid Amide Hydrolase (FAAH)/Monoacylglycerol lipase (MAGL) Inhibitors for Cannabis Use Disorder (CUD).
1TfR43ActfDA057439Projectf01YearfMAKSCIENTIFIC, LLC2023NIDA
NIDA
$320,000
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A CB1 Antagonist for Treatment of Kidney Disease
1TfR44ActfDK139888Projectf01YearfMAKSCIENTIFIC, LLC2024NIDDK
NIDDK
$572,743
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Machine vision guided robotics for automated microinjections into fruit fly embryos
1TfR43ActfOD037625Projectf01A1YearfOBJECTIVE BIOTECHNOLOGY, INC.2024OD
OD
$294,543
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Development of Novel Small Molecule Anti-Fibrotic Agent for the Treatment of Systemic Scleroderma
1TfR41ActfHL167548Projectf01YearfAPIE THERAPEUTICS, INC.2023NHLBI
NHLBI
$452,422
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A wearable high-density MEG system with uOPMs
5TfR44ActfMH118154Projectf04YearfFIELDLINE, INC.2023NIMH
NIMH
$314,559
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Preclinical optimization of a gene therapy for erythromelalgia and chronic pain
5TfU44ActfNS122114Projectf04YearfNAVEGA THERAPEUTICS, INC.2024NINDS
NINDS
$1,528,057
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Preclinical optimization of a gene therapy for erythromelalgia and chronic pain
3TfU44ActfNS122114Projectf04S1YearfNAVEGA THERAPEUTICS, INC.2024NINDS
NINDS
$98,701
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Development of an immunomodulating peptide as a therapy for osteosarcoma in canine and human
5TfR44ActfCA278570Projectf02YearfPHARMAIN CORPORATION2024NCI
NCI
$995,099
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Orphan Non-coding RNA-based Test for Detecting Minimal Residual Disease in Resectable Non-small Cell Lung Cancer
1TfR44ActfCA291369Projectf01A1YearfEXAI BIO, INC.2024NCI
NCI
$1,280,908
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Anatomic Imaging Derived 4D Hemodynamics using Deep Learning
1TfR42ActfHL174259Projectf01A1YearfTHIRD COAST DYNAMICS, INC.2024NHLBI
NHLBI
$656,751
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Development and testing of a digitally assisted risk reduction platform for youth at high risk for suicide
5TfR44ActfMH128484Projectf04YearfKSANA HEALTH, INC.2025NIMH
NIMH
$794,102
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