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2,999 Projects
TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
Smart Laser Capturing Microscope for Genome Wide Single Cell Spatial Transcriptomics
1TfR01ActfHG014004Projectf01YearfUNIVERSITY OF CALIFORNIA-IRVINE2025NHGRI
NHGRI
$260,910
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Whole organ transcriptome reconstruction by dimensionality reduced fluorescent in situ hybridization
5TfR01ActfHG012925Projectf02YearfUNIVERSITY OF CALIFORNIA LOS ANGELES2025NHGRI
NHGRI
$556,890
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Probabilistic Multiscale Modeling of the Tumor Microenvironment
5TfR37ActfCA271186Projectf03YearfSLOAN-KETTERING INST CAN RESEARCH2025NCI
NCI
$625,692
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Light-Seq: Spatially targeted profiling of transcriptomic states in cells and tissue
5TfR01ActfHG012926Projectf03YearfHARVARD UNIVERSITY2025NHGRI
NHGRI
$521,296
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Pioneering assays for spatially-resolved single-cell multiomics
4TfR44ActfHG013294Projectf02YearfSURVEY GENOMICS, INC.2025NHGRI
NHGRI
$1,091,941
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Unsupervised Statistical Methods for Data-driven Analyses in Spatially Resolved Transcriptomics Data
5TfR00ActfHG012229Projectf04YearfBOSTON UNIVERSITY MEDICAL CAMPUS2025NHGRI
NHGRI
$218,876
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Explainable Artificial Intelligence for Melanoma Recurrence Prediction via Integrative Modeling of Multiplexed Imaging with Transcriptomics and Histopathology
5TfK99ActfCA286966Projectf02YearfMASSACHUSETTS GENERAL HOSPITAL2025NCI
NCI
$176,040
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AI-empowered 3D Computer Vision and Image-Omics Integration for Digital Kidney Histopathology
5TfR01ActfDK135597Projectf03YearfVANDERBILT UNIVERSITY2025NIDDK
NIDDK
$516,487
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Diabetes-enhanced Experimental Periodontitis
5TfR01ActfDE017732Projectf15YearfUNIVERSITY OF PENNSYLVANIA2025NIDCR
NIDCR
$413,204
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Core D - Senescence Molecular Phenotyping Core (SMPC)
5TfP01ActfAG062413Projectf07Yearf6877MAYO CLINIC ROCHESTER2025NIA
NIA
$452,579
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An integrated microtechnology platform for spatially resolved mass spectrometry-based proteomics
5TfR01ActfCA283247Projectf03YearfSTANFORD UNIVERSITY2025NCI
NCI
$550,532
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Probing the role of Selenomonas sputigena in supragingival biofilm spatial structuring and virulence
5TfK99ActfDE033428Projectf02YearfUNIVERSITY OF PENNSYLVANIA2025NIDCR
NIDCR
$127,062
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Interrogating The Biology Of Human Lupus Nephritis Using Single Cell Resolution Spatial Transcriptomics
5TfR01ActfDK136980Projectf02YearfSEATTLE CHILDREN'S HOSPITAL2025NIDDK
NIDDK
$742,873
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Integrative Prediction of Therapeutic Response in T-cell Lymphoma by Omic and Spatial Modeling
5TfR00ActfCA256497Projectf05YearfBRIGHAM AND WOMEN'S HOSPITAL2025NCI
NCI
$224,099
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Cavity and Granuloma Oriented Inflammation and Tissue Pharmacokinetics in Pulmonary Tuberculosis (COOK TB)
5TfR01ActfAI173946Projectf03YearfEMORY UNIVERSITY2025NIAID
NIAID
$762,816
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Characterizing Vulnerable Cell Types in C9orf72-FTD
5TfF30ActfAG077858Projectf03YearfUNIVERSITY OF PENNSYLVANIA2025NIA
NIA
$17,574
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Liver disease impact on myeloid cells driving immunotherapy resistance in hepatocellular carcinoma
1TfK08ActfCA290152Projectf01A1YearfUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2025NCI
NCI
$282,053
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Multimodality spatial analysis in prostate cancer to improve prognostic estimation and cast light into the black box of pathology artificial intelligence algorithms
1TfR01ActfCA296792Projectf01YearfUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2025NCI
NCI
$680,433
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Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions
5TfR01ActfAG082127Projectf03YearfUNIVERSITY OF CALIFORNIA-IRVINE2025NIA
NIA
$1,817,870
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Disparate Survival, Disparate Workforce: An Integrated Approach to Improving Head and Neck Cancer Outcomes and Diversity in the Oncology Workforce
5TfR01ActfDE033740Projectf02YearfDUKE UNIVERSITY2025NIDCR
NIDCR
$586,190
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Epigenetic analysis of osteosarcoma to define subclasses relevant to chemoresistance and metastasis
1TfR01ActfCA292790Projectf01A1YearfUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2025NCI
NCI
$540,090
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Mapping the non-coding RNA landscape in skeletal muscle health and disease
5TfR01ActfAR081449Projectf02YearfCORNELL UNIVERSITY2025NIAMS
NIAMS
$642,828
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Control of Intestinal Epithelial Function through Lymphatic-Intestinal Stem Cell Communication
5TfK08ActfDK132518Projectf04YearfSLOAN-KETTERING INST CAN RESEARCH2025NIDDK
NIDDK
$167,617
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Spatial smooth muscle cell transition states in atherosclerosis
1TfF30ActfHL178164Projectf01YearfYALE UNIVERSITY2025NHLBI
NHLBI
$36,958
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Oxytocin receptor signaling modulates social attachment via hippocampal CA2/3 function
5TfK99ActfMH135061Projectf02YearfUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2025NIMH
NIMH
$121,499
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Local cellular communication networks in COPD endotypes
5TfR21ActfHL173512Projectf02YearfYALE UNIVERSITY2025NHLBI
NHLBI
$125,625
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Molecular and functional architecture of a premotor circuit for decision making
5TfR01ActfMH133039Projectf03YearfICAHN SCHOOL OF MEDICINE AT MOUNT SINAI2025NIMH
NIMH
$529,224
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Molecular and anatomical atlases from progenitors to adult neurons in the mouse spinal cord
5TfR01ActfMH134799Projectf02YearfUT SOUTHWESTERN MEDICAL CENTER2025NIMH
NIMH
$1,129,792
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Elucidating the Temporal, Spatial and Cellular Effects of Differential APOE Isoform Expression
5TfR01ActfAG070202Projectf05YearfCOLUMBIA UNIVERSITY HEALTH SCIENCES2025NIA
NIA
$497,502
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Uncovering cell-type-specific driver genes of Alzheimer's Disease by pathology-indexing scRNA-seq, spatial transcriptomics, and CRISPR screens
5TfR01ActfAG074082Projectf04YearfRUSH UNIVERSITY MEDICAL CENTER2025NIA
NIA
$652,226
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Endoplasmic Reticulum Stress in the function of cancer associated fibroblasts in pancreatic cancer
1TfR01ActfCA295509Projectf01YearfHENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES2025NCI
NCI
$435,144
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Molecular architecture of the human knee joint and pelvis at single cell resolution
5TfR01ActfAR081274Projectf03YearfHARVARD UNIVERSITY2025NIAMS
NIAMS
$666,865
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Characterization of the spatial and temporal response to tau in chronic traumatic encephalopathy
1TfR01ActfAG090553Projectf01YearfBOSTON UNIVERSITY MEDICAL CAMPUS2025NIA
NIA
$817,484
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Center for 3D Imaging in Cancer Cell Biology
5TfU54ActfCA268083Projectf04YearfJOHNS HOPKINS UNIVERSITY2025NCI
NCI
$1,531,820
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The adaptive-innate immune interactome across multiple tissues in Alzheimer's disease
5TfR01ActfAG082185Projectf03YearfICAHN SCHOOL OF MEDICINE AT MOUNT SINAI2025NIA
NIA
$1,969,360
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Function and Transcriptional Regulation of Leiomodin1
1TfR01ActfHL173111Projectf01A1YearfAUGUSTA UNIVERSITY2025NHLBI
NHLBI
$768,198
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Generation of new neurons in the aging adult brain: identifying mechanisms of adult neurogenesis by exploiting single cell spatial transcriptomics.
1TfK99ActfAG090813Projectf01YearfUNIVERSITY OF CALIFORNIA, SAN DIEGO2025NIA
NIA
$126,956
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Dissecting spatiotemporal heterogeneity of glioblastoma evolution under therapy
5TfK99ActfCA286730Projectf02YearfUNIVERSITY OF MIAMI SCHOOL OF MEDICINE2025NCI
NCI
$113,995
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Role of complement in injury-induced cystogenesis among carriers of a single ADPKD gene defect
5TfI01ActfBX006266Projectf02YearfBIRMINGHAM VA MEDICAL CENTER2025VAView View Similar Projects Similar Projectsf
Elucidating Host Responses to AAV Ocular Gene Therapy Vectors
5TfF31ActfEY035867Projectf02YearfHARVARD MEDICAL SCHOOL2025NEI
NEI
$36,918
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Identifying transcriptomic axes governing neural dynamics, behavior, and states
1TfK99ActfMH138830Projectf01YearfHARVARD UNIVERSITY2025NIMH
NIMH
$120,015
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Understanding the cellular and functional changes in the immune tumor microenvironment of glioblastoma during progression and treatments.
5TfR01ActfCA271601Projectf03YearfBETH ISRAEL DEACONESS MEDICAL CENTER2025NCI
NCI
$583,542
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Single cell and spatial genomic analyses of specimens from patients with autoimmune diseases (Technology Core)
5TfUC2ActfAR081031Projectf04YearfBRIGHAM AND WOMEN'S HOSPITAL2025NIAMS
NIAID
NIAMS
$100,000
$200,000
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Dynamic regulatory mechanisms of robust pattern formation in the neural tube
2TfR01ActfGM154339Projectf09A1YearfHARVARD MEDICAL SCHOOL2025NIGMS
NIGMS
$364,590
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A spatially resolved molecular atlas of acute viral myocarditis at single-cell resolution
5TfR01ActfAI176681Projectf03YearfCORNELL UNIVERSITY2025NIAID
NIAID
$753,450
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Investigating the anti-inflammatory mechanisms of calorie restriction in the aged lacrimal gland
5TfR01ActfEY035333Projectf02YearfSCRIPPS RESEARCH INSTITUTE, THE2025NEI
NEI
$695,347
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Investigating the role of human-specific 3D genome conformation in the context of brain development and disease
1TfR01ActfMH138495Projectf01YearfOREGON HEALTH & SCIENCE UNIVERSITY2025NIMH
NIMH
$800,485
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The effect of aging on cDC1 function and CD8 T cell immunity in tumors
1TfK99ActfCA296769Projectf01YearfMASSACHUSETTS GENERAL HOSPITAL2025NCI
NCI
$176,040
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Graph Learning of Cell-cell Communications in Spatial Transcriptomics
5TfR01ActfLM014087Projectf04YearfYALE UNIVERSITY2025NLM
NLM
$308,545
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Mapping the functional GPCR-ome and its signaling consequences in neurons
5TfF32ActfMH136662Projectf02YearfUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2025NIMH
NINDS
$79,284
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