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2,766 Projects
Fiscal Year: Active ProjectsFunding Mechanism: SBIR/STTR, Non-SBIR/STTR Contracts
TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
Targeting Type 3 Diabetes (T3D) Mechanism of Alzheimer's Disease (AD) and AD-Related Dementias
5TfR43ActfAG085738Projectf02YearfREGENE LLC2025NIA
NIA
$249,995
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Addressing adoption barriers to patient transportation services
5TfR44ActfNR020320Projectf03YearfTRANSCENDENT INTERNATIONAL, LLC2025NINR
NINR
$734,677
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A physiologically relevant pre-clinical drug screening platform for Alzheimer's Disease and Traumatic Brain Injury with integrated stretchable microelectrodes
5TfR44ActfAG079777Projectf03YearfBMSEED, LLC2025NIA
NIA
$779,587
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Development of a novel anti-neuroinflammatory experimental therapeutic for epilepsy and Alzheimer's risk
5TfR44ActfAG071062Projectf03YearfIMMUNOCHEM THERAPEUTICS, LLC2025NIA
NIA
$1,209,751
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Meeting the cost and privacy demands for detecting Anabolic Androgenic Steroid doping in youth athletics with rationally designed nuclear receptor BioAssays
1TfR43ActfDA059306Projectf01A1YearfXCELLASSAY, INC.2025NIDA
NIDA
$306,872
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Research and cloud deployment of enhanced sampling methods in MovableType
5TfR44ActfGM148103Projectf03YearfQUANTUMBIO, INC.2025NIGMS
NIGMS
$654,406
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Chikungunya Recombinant Subunit Vaccine
5TfR44ActfAI120388Projectf06YearfHAWAII BIOTECH, INC.2025NIAID
NIAID
$998,229
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A Novel Waveguide to Enable MAS-DNP-NMR in Standard-bore High-field Magnets
5TfR44ActfGM139468Projectf04YearfDOTY SCIENTIFIC, INC.2025NIGMS
NIGMS
$791,121
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Improved Sirolimus-Analog Adventitial Delivery to Enhance Outcomes in Below-the-Knee Peripheral Artery Disease
5TfR44ActfHL102998Projectf05YearfMERCATOR MEDSYSTEMS, INC.2025NHLBI
NHLBI
$1,000,000
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Development of a Universal Assay for Minimal Residual Disease in Acute Myeloid Leukemia using Duplex Sequencing
5TfR44ActfCA233381Projectf06YearfTWINSTRAND BIOSCIENCES, INC.2025NCI
NCI
$1,985,831
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Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)
5TfR44ActfNS125745Projectf03YearfEVON MEDICS, LLC2025NINDS
NINDS
$1,280,870
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Prapela® SVS incubator pad: A cost-effective stochastic vibrotactile device to improve the clinical course of infants with apnea of prematurity.
5TfU44ActfDA059380Projectf03YearfPRAPELA, INC.2025NIDA
NIDA
$1,475,909
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Multiplexed Assay for Point-of-Care UTI Diagnosis (ID/AMR)
5TfR44ActfAI181154Projectf02YearfNANOPATHDX, INC.2025NIAID
NIAID
$964,943
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A novel CAR-T cell therapy for the one-time treatment of chronic HIV infection in patients who are not ART suppressed
5TfR42ActfAI167175Projectf03YearfMARPAM PHARMA, LLC2025NIAID
NIAID
$979,050
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Phase IIB Plasticity-based Adaptive Cognitive Remediation for Alzheimers Disease
5TfR44ActfAG047722Projectf09YearfPOSIT SCIENCE CORPORATION2025NIA
NIA
$826,900
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A high-efficiency, low-cost, single-use purification technology for therapeutic antibody manufacturing
5TfR44ActfGM134776Projectf05YearfBONDWELL TECHNOLOGIES LP2025NIGMS
NIGMS
$1,155,951
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Development of a Route of Exposure Model Using Silicone Wristbands as Personal Samplers
5TfR44ActfES033586Projectf03YearfMYEXPOSOME, INC.2025NIEHS
NIEHS
$1,036,597
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Novel Post-surgical Incision Management Device to Prevent Ostomy Complications
5TfR44ActfDK131766Projectf03YearfFISTULA SOLUTION CORPORATION2025NIDDK
NIDDK
$483,306
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Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation
5TfR44ActfDC019586Projectf05YearfRESTOREAR DEVICES, LLC2025NIDCD
NIDCD
$329,169
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Development of a web-based platform implementing novel Predictor of Toxicity for Medical Devices (PredTox/MD)
5TfR44ActfES032371Projectf03YearfPREDICTIVE, LLC2025NIEHS
NIEHS
$287,526
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Development and testing of a digitally assisted risk reduction platform for youth at high risk for suicide
5TfR44ActfMH128484Projectf04YearfKSANA HEALTH, INC.2025NIMH
NIMH
$794,102
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Development of a Totally Implanted Left Ventricular Assist Device
1TfR44ActfHL177945Projectf01YearfCORVION, INC.2025NHLBI
NHLBI
$1,024,635
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Synthetic biology approaches for bio-orthogonal labeling of circular RNAs
1TfR43ActfGM157885Projectf01YearfCHIMERNA THERAPEUTICS INC.2025NIGMS
NIGMS
$302,605
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A Novel Bispecific Antibody for the Treatment of Idiopathic Pulmonary Fibrosis
5TfR44ActfHL164202Projectf04YearfVIRTICI, LLC2025NHLBI
NHLBI
$999,989
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eMOA: A Multi-Omic Service for Mechanism of Action Determination in Drug Screening
4TfR44ActfGM154583Projectf02YearfECLIPSE BIOINNOVATIONS INC2025NIGMS
NIGMS
$1,148,465
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A Rapid, Point-of-Care Diagnostic to Identify Viable Sexually Transmitted Infections, Reduce Overtreatment, and Prevent Emerging Antibiotic Resistance
1TfR44ActfAI188680Projectf01YearfBAEBIES, INC.2025NIAID
NIAID
$300,000
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Enhancing Healthcare Delivery and Patient Outcomes: Noninvasive Wireless Sensors to Improve Ventricular Shunt Monitoring, Reduce Imaging, and Alleviate the Burden on Providers, Patients, and Families
2TfR44ActfNS121555Projectf04YearfRHAEOS, INC.2025NINDS
NINDS
$966,022
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Manufacturing Process Intensification for Pluripotent Stem Cell-Derived Rare Red Cell Production
1TfR41ActfHL178144Projectf01YearfSAFI BIOTHERAPEUTICS INC2025NHLBI
NHLBI
$568,264
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Resubmission - Development and scale-up of Continuous Countercurrent Tangential Chromatography (CCTC) for next generation AAV vector manufacturing (Direct to Phase II)
5TfR44ActfGM154572Projectf02YearfCHROMATAN CORPORATION2025NIGMS
NIGMS
$695,448
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High-content study to analyze the nutritional value of natural products for healthy aging
1TfR43ActfAT013187Projectf01YearfVIVOVERSE, LLC2025NCCIH
NCCIH
$306,793
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Bearingless flux reversal motor for neonatal and pediatric extracorporeal life support applications
1TfR44ActfHL178134Projectf01YearfENSION, INC.2025NHLBI
NHLBI
$870,467
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Autonomous Monitor for Toxic Gas Exposure
5TfR44ActfES032369Projectf03YearfZEBRA ANALYTIX, INC.2025NIEHS
NIEHS
$919,218
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Automated identification of larval mosquito species with computer vision
5TfR43ActfAI184319Projectf02YearfVECTECH, LLC2025NIAID
NIAID
$107,987
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Clinical validation of Duoseq, a Swiss army knife genomic approach to diagnosis of blood cancers
1TfR43ActfCA298055Projectf01YearfDATA DRIVEN BIOSCIENCE INC2025NCI
NCI
$300,682
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Magnetic Lipid Nanoprobe Platform for Rapid, Highly-Efficient, and Cost-Effective Isolation of Extracellular Vesicles from Non-Invasive Bodily Fluids
1TfR44ActfTR005339Projectf01A1YearfCAPTIS DIAGNOSTICS2025NCATS
NCATS
$1,077,369
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IL-10NanoCap® for Therapy of Familial Adenomatous Polyposis
5TfR44ActfDK117687Projectf06YearfTHERAPYX, INC.2025NIDDK
NIDDK
$959,868
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iPSC-derived human neurons and OUD medications development
1TfR43ActfDA062459Projectf01YearfCHEMREGEN INC2025NIDA
NIDA
$399,536
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Commercialization Readiness for a Portable PET Insert System for Simultaneous TOF-PET and MR Brain Imaging
1TfSB1ActfMH139143Projectf01YearfPETCOIL, INC.2025NIMH
NIMH
$1,596,935
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Development of CM-HZ01 as a non-alpha-IL2 therapeutic for the treatment of metastatic melanoma
1TfR44ActfCA298512Projectf01YearfCELDARA MEDICAL, LLC2025NCI
NCI
$1,024,967
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Cloud/Web-Based Platform for Quantitative SPECT Reconstruction of Therapeutic Radionuclides
1TfR44ActfCA291419Projectf01A1YearfRADIOPHARMACEUTICAL IMAGING AND DOSIMETRY, LLC2025NCI
NCI
$1,003,173
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Nebulized ALX1 as a treatment for Pseudomonas aeruginosa infections in bronchiectasis patients
1TfR44ActfAI184225Projectf01A1YearfVAST THERAPEUTICS, INC.2025NIAID
NIAID
$1,000,000
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Allogeneic cell and gene therapy for neuroendocrine tumors
1TfR43ActfCA291373Projectf01A1YearfEXPRESSION THERAPEUTICS2025NCI
NCI
$400,000
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Mini-reflectance confocal microscope (Mini-RCM) for aiding skin cancer diagnosis and treatment
1TfR41ActfCA298754Projectf01YearfARGOSMD, INC.2025NCI
NCI
$400,000
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Building and testing the Life Enhancement and Advocacy Programming digital training tool (LEAPLink) to better serve people with lived experience of homelessness and substance use disorder
1TfR41ActfDA062292Projectf01YearfHART3S - A SOCIAL PURPOSE CORPORATION2025NIDA
NIDA
$306,678
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Novel Cyclic Boronate Cell Wall Inhibitors Targeting Carbapenem-Resistant Acinetobacter baumannii
5TfR44ActfAI181353Projectf02YearfVENATORX PHARMACEUTICALS, INC.2025NIAID
NIAID
$1,000,000
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Bioinformatics pipeline for personalized diagnostics of transplant rejection
1TfR41ActfAI189162Projectf01YearfDATIRIUM, LLC2025NIAID
NIAID
$306,500
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In vitro metabolite profiling with vibrational phase-contrast imaging
1TfR43ActfGM157792Projectf01YearfTRESTLE OPTICS LLC2025NIGMS
NIGMS
$330,076
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A digital intervention to decrease self-stigma among pregnant and postpartum women with opioid use disorder
4TfR44ActfDA055161Projectf02YearfRISSANA, LLC2025NIDA
NIDA
$917,927
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Development of a Navigation-Based Insertion Tool for Trajectory Optimization during Cochlear Implantation
1TfR43ActfDC022201Projectf01A1YearfIOTAMOTION, INC.2025NIDCD
NIDCD
$306,073
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Rapid Fingerstick Diagnostics for Opioid and Stimulant Use Disorders
1TfR43ActfDA063260Projectf01YearfELECTRONIC BIOSCIENCES, INC.2025NIDA
NIDA
$386,452
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