A mobile health tool to improve antibiotic stewardship among village doctors in Bangladesh
Project Number4R33HD109819-03
Former Number5R21HD109819-02
Contact PI/Project LeaderLEUNG, DANIEL TED Other PIs
Awardee OrganizationUNIVERSITY OF UTAH
Description
Abstract Text
Abstract
Diarrheal diseases are the among the leading cause of death in children worldwide, most of which occur in
low- and middle-income countries (LMICs). The cornerstone for management of diarrhea is rehydration, though
antimicrobials are beneficial in some instances. Unfortunately, given that treatment is frequently empiric, based
mostly on clinical suspicion for bacterial causes, antimicrobials are overused in management of diarrheal
illness worldwide. Thus, there is a need for clinical decision support tools to inform clinical management and
promote antimicrobial stewardship. In particular, frontline healthcare providers in rural areas, such as village
doctors in Bangladesh, often have inadequate knowledge for the basis of antimicrobial use, and may benefit
greatly from guidance. We have recently developed a mobile phone based electronic clinical decision-support
tool (eCDST), and shown the impact of etiological prediction on physician antibiotic prescription practices for
pediatric diarrhea in two LMICs. In this proposal, our overarching goal is to customize our eCDST into a
comprehensive mHealth application (Accessible Diarrhea Etiology Prediction Tool, ADEPT) to support rural
health care providers in the management of pediatric diarrhea (R21 phase), and to measure its impact through
the performance of a pilot before-after feasibility study (R33 phase). Our work will contribute to an evidence
base for mHealth-enabled antimicrobial stewardship, with potential to extend beyond diarrheal illness, and into
other syndromes, including respiratory illness and febrile illness.
Public Health Relevance Statement
Project Narrative
Diarrheal diseases are a leading cause of morbidity and mortality in children worldwide. Appropriate
management of childhood diarrhea depends on the type of pathogen responsible, but in many cases testing is
not affordable or feasible. We propose to develop and validate a tool for rural healthcare workers that predicts
etiology for pediatric diarrhea, and supports clinical decision making.
Eunice Kennedy Shriver National Institute of Child Health and Human Development
CFDA Code
865
DUNS Number
009095365
UEI
LL8GLEVH6MG3
Project Start Date
12-September-2024
Project End Date
31-August-2027
Budget Start Date
12-September-2024
Budget End Date
31-August-2025
Project Funding Information for 2024
Total Funding
$298,640
Direct Costs
$231,275
Indirect Costs
$67,365
Year
Funding IC
FY Total Cost by IC
2024
Eunice Kennedy Shriver National Institute of Child Health and Human Development
$298,640
Year
Funding IC
FY Total Cost by IC
Sub Projects
No Sub Projects information available for 4R33HD109819-03
Publications
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Outcomes
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No Outcomes available for 4R33HD109819-03
Clinical Studies
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History
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