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Fiscal Year: Active ProjectsActivity Code: k99IC Code: caOpportunity Number: rfa-ca

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TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
Elucidating the role of hepatic ketogenesis in pancreatic cancer cachexia and recovery
5TfK99ActfCA286709Projectf02Yearf
ARNESON-WISSINK, PAIGE C Principal Investigator(s)/ Project Leader(s)
OREGON HEALTH & SCIENCE UNIVERSITY2025NCI
NCI
$118,041
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Dissecting the Role of Germline Genetics in RAS-Driven Cancers
5TfK99ActfCA286805Projectf02Yearf
COLLINS, RYAN LEWIS Principal Investigator(s)/ Project Leader(s)
DANA-FARBER CANCER INST2025NCI
NCI
$163,728
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Assessing how multilevel factors shape disparities in cancer screening
5TfK99ActfCA277552Projectf02Yearf
DEL VECCHIO, NATALIE Principal Investigator(s)/ Project Leader(s)
FRED HUTCHINSON CANCER CENTER2024NCI
NCI
$209,250
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Dietary Control of the Pro-Metastatic Niche in Colorectal Cancer
5TfK99ActfCA287057Projectf02Yearf
GOSWAMI, SWAGATA Principal Investigator(s)/ Project Leader(s)
MASSACHUSETTS INSTITUTE OF TECHNOLOGY2025NCI
NCI
$142,301
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Influence of Social Determinants of Health and Epigenomics on Psychological Symptom Cluster Severity
5TfK99ActfCA286967Projectf02Yearf
HARRIS, CAROLYN STIGGE Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF PITTSBURGH AT PITTSBURGH2025NCI
NCI
$161,556
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Integration of multi-omics to predict and evaluate response during optimization of a nutrition intervention for cancer survivors with overweight and obesity
5TfK99ActfCA287061Projectf02Yearf
HILL, EMILY B. Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF COLORADO DENVER2025NCI
NCI
$116,924
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Quantitative modeling of extrachromosomal DNA (ecDNA) evolution in tumors
5TfK99ActfCA286968Projectf02Yearf
JONES, MATTHEW GREGORY Principal Investigator(s)/ Project Leader(s)
STANFORD UNIVERSITY2025NCI
NCI
$167,508
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Functional Landscape of Glycosylation in Skin Cancer
5TfK99ActfCA277591Projectf02Yearf
KUDELKA, MATTHEW ROBERT Principal Investigator(s)/ Project Leader(s)
ROCKEFELLER UNIVERSITY2024NCI
NCI
$178,427
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Large-scale artificial intelligence using radiomics, deep learning, and physics-based generative modeling to improve clinical outcomes in nuclear medicine
5TfK99ActfCA287045Projectf02Yearf
LEUNG, KEVIN HO-YIN Principal Investigator(s)/ Project Leader(s)
JOHNS HOPKINS UNIVERSITY2025NCI
NCI
$170,100
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Targeting Cancer at the Protein-Membrane Interface
5TfK99ActfCA277358Projectf02Yearf
MORSTEIN, JOHANNES Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO2024NCI
NCI
$163,080
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Recognition of ribonucleoprotein (RNP) substrate by the poly(A) exosome targeting (PAXT) complex
5TfK99ActfCA267555Projectf02Yearf
PARK, MI SEUL Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2023NCI
NCI
$119,176
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Learning about the effectiveness of lung cancer screening in real-world target populations
5TfK99ActfCA287059Projectf02Yearf
ROBERTSON, SARAH E Principal Investigator(s)/ Project Leader(s)
HARVARD SCHOOL OF PUBLIC HEALTH2025NCI
NCI
$128,773
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A multi-omics approach to evaluate the role of chronic inflammation in breast cancer development
5TfK99ActfCA286891Projectf02Yearf
ROMANOS-NANCLARES, ANDREA Principal Investigator(s)/ Project Leader(s)
BRIGHAM AND WOMEN'S HOSPITAL2025NCI
NCI
$164,570
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Causal determinants of drug resistance and metastasis in cancer with multimodal single cell data
5TfK99ActfCA277562Projectf02Yearf
SALEHI, SOHRAB Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2024NCI
NCI
$115,926
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Quantitatively predicting drug-resistant mutations to improve precision oncology
1TfK99ActfCA286801Projectf01Yearf
SINGH, SUKRIT Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2024NCI
NCI
$144,056
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AI-Powered Uncovering of Mechanisms in Cancer Through Causal Discovery Analysis and Generative Modeling of Heterogeneous Data
5TfK99ActfCA277583Projectf02Yearf
STOJANOV, PETAR Principal Investigator(s)/ Project Leader(s)
BROAD INSTITUTE, INC.2024NCI
NCI
$138,349
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Do Tumor-Immune Interactions Prime Systemic Tolerance of Triple-Negative Breast Cancer Brain Metastases?
5TfK99ActfCA256522Projectf02Yearf
UMEH GARCIA, MAXINE CHIDINMA Principal Investigator(s)/ Project Leader(s)
STANFORD UNIVERSITY2022NCI
NCI
$162,617
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Explainable Artificial Intelligence for Melanoma Recurrence Prediction via Integrative Modeling of Multiplexed Imaging with Transcriptomics and Histopathology
5TfK99ActfCA286966Projectf02Yearf
WAN, GUIHONG Principal Investigator(s)/ Project Leader(s)
MASSACHUSETTS GENERAL HOSPITAL2025NCI
NCI
$176,040
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Breaching the Tumor-Immune Mechanical Barrier for Optimal Antitumor Immunity
5TfK99ActfCA286969Projectf02Yearf
WU, BOGANG Principal Investigator(s)/ Project Leader(s)
MASSACHUSETTS GENERAL HOSPITAL2025NCI
NCI
$176,040
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Defining mechanisms of metabolic-epigenetic crosstalk that drive glioma initiation
5TfK99ActfCA277576Projectf02Yearf
XIAO, YI Principal Investigator(s)/ Project Leader(s)
UT SOUTHWESTERN MEDICAL CENTER2024NCI
NCI
$124,200
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