Using mindfulness-based cognitive therapy to manage pain and mitigate suicide risk in Veterans
Project Number5R34AT011004-03
Former Number1R34AT011004-01
Contact PI/Project LeaderASHRAFIOUN, LISHAM
Awardee OrganizationVETERANS HEALTH RESEARCH INSTITUTE OF CENTRAL NEW YORK, INC.
Description
Abstract Text
The proposed study will develop a mindfulness-based cognitive therapy (MBCT) manual to address both
functional impairment and suicide risk (MBCT-S/P). We will examine the feasibility of the study design and ask
participants if the found the treatment to be acceptable. We expect this smaller study will provide critical
information for a larger trial.
Suicide is the 10th leading cause of death. Chronic pain is a leading cause of functional impairment in the
United States and is a risk factor of suicide even after accounting for psychiatric disorders. Veterans are a
vulnerable population for both suicide and chronic pain; however, there is little research examining ways to
reduce functional impairment and suicide risk in a combined treatment. Therefore, this proposal examines the
use of MBCT as a novel way to simultaneously address functional impairment and suicide risk. Research on
patients at risk of suicide and on patients experiencing chronic pain supports the utility of MBCT separately.
However, there is limited evidence investigating a combined treatment that addresses both functional
impairment and suicide risk. Application of MBCT on veterans at risk for suicide who are experiencing
functionally-impairing chronic pain provides a unique opportunity to simultaneously address these interactive
factors.
The overall goal of the broader program is to enhance functioning and to reduce veteran suicide, and the
proposed project will provide data to guide the development of a larger trial. The objectives of the current
proposal are to (1) combine existing MBCT intervention protocols to develop an MBCT manual aimed at
addressing the unique needs of veterans experiencing functional impairment from chronic pain who are at risk
for suicide, (2) examine if the recruitment, retention, and treatment delivery is feasible and if MBCT-S/P
acceptable to participants, and (3) assess parameters of key outcomes among participants randomized to
receive MBCT-S/P versus an Education control to inform a subsequent larger clinical trial.
To achieve these objectives, we will develop a manual through an evidence-based, iterative process then
conduct a randomized clinical trial in Veterans with chronic pain reporting suicidal ideation. We will randomize
a total of 76 participants to receive either MBCT-S/P or Education. We will assess pain and suicide risk
outcomes such as suicidal ideation, depression, and interpersonal factors at baseline and after the treatment
period. We will also track participant flow, therapist adherence to the manual, participant homework completion
and participant satisfaction with the treatment.
Public Health Relevance Statement
Military veterans are more vulnerable to experience chronic pain, experience psychiatric disorders, and die by
suicide; however, extant research has yet to examine interventions to address suicide risk and functional
impairment from chronic pain within the same intervention. Mindfulness-based cognitive therapy has
demonstrated promise for individuals experiencing chronic pain and for individuals at risk for suicide,
individually, but no study has combined these treatments for more robust effects on each of these outcomes.
Therefore, we plan to develop a manual to address both functional impairment and suicide risk then assess its
feasibility, acceptability, and parameters on key functioning outcomes.
NIH Spending Category
No NIH Spending Category available.
Project Terms
AccountingAddressAdherenceAftercareCause of DeathClinical TrialsCombined Modality TherapyConsensusDataDevelopmentDiagnostic FactorEducationElementsFeasibility StudiesFeeling suicidalFunctional impairmentGoalsGrantIndividualInterventionManualsMental DepressionMental disordersMeta-AnalysisMethodsMind-Body InterventionNational Center for Complementary and Integrative HealthOpioidOutcomeOutcome MeasureOverdosePainPain MeasurementPain intensityPain interferencePain managementParticipantPatientsPhasePremature MortalityProcessProtocols documentationPublic HealthQuality of lifeRandomizedReportingResearchResearch DesignResearch PriorityRiskRisk FactorsSamplingSeveritiesSuicideTestingTherapeutic InterventionThinkingTreatment EfficacyUnited StatesVeteransVulnerable Populationsacceptability and feasibilitychronic paindesignefficacy trialevidence baseexperiencefollow-upfunctional improvementideationinnovationmilitary veteranmind/bodymindfulness based cognitive therapymindfulness interventionneuralnon-opioid analgesicnovelopioid usepain catastrophizingpain outcomeprogramspsychologicrandomized, clinical trialsrecruitreducing suicideresponsesatisfactionsuicidalsuicidal behaviorsuicidal risktreatment duration
National Center for Complementary and Integrative Health
CFDA Code
213
DUNS Number
606310928
UEI
XEAHMC2S4Z95
Project Start Date
10-March-2022
Project End Date
28-February-2026
Budget Start Date
01-March-2024
Budget End Date
28-February-2026
Project Funding Information for 2024
Total Funding
$204,705
Direct Costs
$170,907
Indirect Costs
$33,798
Year
Funding IC
FY Total Cost by IC
2024
National Center for Complementary and Integrative Health
$204,705
Year
Funding IC
FY Total Cost by IC
Sub Projects
No Sub Projects information available for 5R34AT011004-03
Publications
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No Publications available for 5R34AT011004-03
Patents
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Outcomes
The Project Outcomes shown here are displayed verbatim as submitted by the Principal Investigator (PI) for this award. Any opinions, findings, and conclusions or recommendations expressed are those of the PI and do not necessarily reflect the views of the National Institutes of Health. NIH has not endorsed the content below.
No Outcomes available for 5R34AT011004-03
Clinical Studies
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History
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Similar Projects
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