Pediatric Gastroenterology Research Training Program
Project Number5T32DK077653-32
Former Number2T32DK077653-31
Contact PI/Project LeaderTARR, PHILLIP I
Awardee OrganizationWASHINGTON UNIVERSITY
Description
Abstract Text
PROJECT SUMMARY/ABSTRACT
The goal of this training grant is to equip junior investigators with the skills to make enduring contributions to
child digestive health, which encompasses processes that are critical for the survival, growth, and well-being
of people and populations. We achieve this goal by providing immersive research training at Washington
University in fields relevant to digestive health of children worldwide. The rationale for our training program is
based on two premises: (1) high quality early career training is critical for producing individuals who will make
meaningful and lasting impact on the field, and (2) too few individuals are adequately trained to solve problems
relevant to the childhood digestive system. Mentors across all disciplines share dedication to research
relevant to digestive health of children, have strong training records, are very well supported by federal and
foundation grants, and integrate our T32 trainees into existing projects to prepare them for productive scholarly
careers. Track I (Microbial–Host interactions in the Gastrointestinal Tract) trainees determine how gut
pathogens and microbial populations beneficially or harmfully affect childhood digestive health. Track II
(Cellular and Molecular Biology of the Developing Gastrointestinal Tract) trainees dissect molecular and
genetic aspects of congenital and acquired disorders of the childhood gastrointestinal system and host
response to inflammatory stimuli. Track III (Translational Biology of the Gastrointestinal Tract) trainees use
data from humans and populations to further knowledge of digestive disorders of childhood. This program will
fund four post-doctoral (MD, PhD, or MD-PhD) drawn from our traditional base of pediatric gastroenterology
fellows and post-doctoral trainees, strengthened in the past five years by extension to surgical residents. We
will also fund members of the expanding community of PhD and MSTP students interested in the problems we
strive to solve by also funding pre-doctoral candidates and Medical Scientist Training Program enrollees.
Applicants to the program will receive two years of highly mentored support, including an external mentor
system. We will also expand our portfolio of training opportunities to include large data base analysis,
nationwide cohort study training, and implementation science. We will also co-sponsor an annual retreat
focused on issues of diversity, equity, and inclusivity in our training, research, and clinical care. The program
will also remain integrated into the Washington University Digestive Diseases Research Core Center
(DDRCC). The trainees we fund also strengthen multilevel collaborations between gastroenterology and
surgical research in our institution. Our intent is to produce scientists with enduring interests in childhood
digestive diseases and their causes, treatments, and prevention, by our cohorts of trainees and mentors who
share complementary goals and skills.
Public Health Relevance Statement
PROJECT NARRATIVE
The digestive health of children influences the health of populations throughout the life span. Pathobiology
beginning in childhood often has irreversible consequences (e.g., obesity, inflammatory bowel disease) in
children, adolescents, adults, families and communities. We provide rigorous training to young scientists from
diverse disciplines so they can prevent or cure these daunting problems.
National Institute of Diabetes and Digestive and Kidney Diseases
CFDA Code
847
DUNS Number
068552207
UEI
L6NFUM28LQM5
Project Start Date
01-July-1991
Project End Date
30-April-2028
Budget Start Date
01-May-2024
Budget End Date
30-April-2025
Project Funding Information for 2024
Total Funding
$504,095
Direct Costs
$474,236
Indirect Costs
$29,859
Year
Funding IC
FY Total Cost by IC
2024
National Institute of Diabetes and Digestive and Kidney Diseases
$504,095
Year
Funding IC
FY Total Cost by IC
Sub Projects
No Sub Projects information available for 5T32DK077653-32
Publications
Publications are associated with projects, but cannot be identified with any particular year of the project or fiscal year of funding. This is due to the continuous and cumulative nature of knowledge generation across the life of a project and the sometimes long and variable publishing timeline. Similarly, for multi-component projects, publications are associated with the parent core project and not with individual sub-projects.
No Publications available for 5T32DK077653-32
Patents
No Patents information available for 5T32DK077653-32
Outcomes
The Project Outcomes shown here are displayed verbatim as submitted by the Principal Investigator (PI) for this award. Any opinions, findings, and conclusions or recommendations expressed are those of the PI and do not necessarily reflect the views of the National Institutes of Health. NIH has not endorsed the content below.
No Outcomes available for 5T32DK077653-32
Clinical Studies
No Clinical Studies information available for 5T32DK077653-32
News and More
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History
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Similar Projects
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