Contact PI/Project LeaderSEMENKOVICH, CLAY F. Other PIs
Awardee OrganizationWASHINGTON UNIVERSITY
Description
Abstract Text
Project Summary
The long term objective of this competitive renewal application is to train exceptional diabetes scientists
capable of leveraging the latest research tools to decrease suffering from diabetes. The program trains MD,
PhD, and MD PhD scientists for 2 to 3 years through mentored research and structured activities that are
seamlessly integrated with basic science departments, clinical departments, and centers in the context of
considerable institutional support. Continually evolving in response to self-assessment and external reviews,
the training program features strengths that include: A) Research facilities and a research environment
encompassing the Institute of Clinical and Translational Sciences (the Washington University CTSA), the
NIDDK-supported Diabetes Research Center (DRC) and Nutrition Obesity Research Center (NORC), as well
as substantial other resources. B) A required core curriculum in diabetes science in addition to required
supplemental courses that include training in Rigor and Reproducibility all provided at no cost to trainees. C)
Administrative support to facilitate interdisciplinary and multidisciplinary research training. D) Two Program
Directors with complementary skill sets, strong records of training scholars, and significant commitment of
effort through institutional support. E) 30 preceptors focused on diabetes and related metabolic diseases. Over
the past 10 years, this group has trained >270 postdoctorates of whom 86% have continued in research. Each
of the mentors participates in one or more components of this training program, and each has external
research support (average current year support >$990,000/preceptor). F) Institution of a new mentoring
curriculum that has improved mentoring as determined by anonymous surveys. G) Highly competitive pools of
PhD and clinical degree trainees. All available postdoctoral positions have been filled over the past 15 years
and the program completion rate is 96%. H) Anonymous feedback from current and former trainees indicating
increased satisfaction with the training program over the most recent funding period. I) Successful training
record in terms of publications (a substantial increase in publications per trainee compared to the previous
funding period), competing for grant support, and remaining in research or research-related careers. J) To
enhance diversity, institution of a new underrepresented minority (URM) Metabolic Outreach Program allowing
URM scientists from the University of Miami to undergo short-term research training at Washington University.
One URM MD fellow has completed such training. K) An integrated short-term research program for medical
students coordinated through the Washington University DRC. Overall, this training program prepares a
diverse group of scientists across the translational spectrum to exert a sustained influence on research in
diabetes and related metabolic diseases.
Public Health Relevance Statement
Project Narrative
About 30 million Americans have diabetes, another 84 million have prediabetes, and nearly a quarter of health
care expenditures are for diabetes and its complications. In addition to economic costs, metabolic diseases like
diabetes cause enormous suffering due to heart disease, kidney failure, liver failure, strokes, amputations and
many other health problems. This application is relevant to public health because of its overarching goal of
training exceptional scientists capable of developing new strategies to decrease the burden of diabetes in the
United States.
National Institute of Diabetes and Digestive and Kidney Diseases
CFDA Code
847
DUNS Number
068552207
UEI
L6NFUM28LQM5
Project Start Date
01-July-1975
Project End Date
30-June-2025
Budget Start Date
01-July-2024
Budget End Date
30-June-2025
Project Funding Information for 2024
Total Funding
$1,010,582
Direct Costs
$939,245
Indirect Costs
$71,337
Year
Funding IC
FY Total Cost by IC
2024
National Institute of Diabetes and Digestive and Kidney Diseases
$1,010,582
Year
Funding IC
FY Total Cost by IC
Sub Projects
No Sub Projects information available for 5T32DK007120-50
Publications
Publications are associated with projects, but cannot be identified with any particular year of the project or fiscal year of funding. This is due to the continuous and cumulative nature of knowledge generation across the life of a project and the sometimes long and variable publishing timeline. Similarly, for multi-component projects, publications are associated with the parent core project and not with individual sub-projects.
No Publications available for 5T32DK007120-50
Patents
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Outcomes
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No Outcomes available for 5T32DK007120-50
Clinical Studies
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News and More
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History
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