RePORT ⟩ RePORTER

T	Act	Project	Year	Sub	Principal Investigator(s)/ Project Leader(s)	Organization	Fiscal Year	Admin IC	Funding IC	FY Total Cost by IC	Similar Projects
Core A. Administrative Core
5Tf	P50Actf	HD103526Projectf	02Yearf	7832	ABBEDUTO, LEONARD J. Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF CALIFORNIA AT DAVIS	2021	NICHD	NICHD	$156,292	View View Similar Projects Similar Projectsf
Alzheimer's Clinical Trials Consortium (ACTC)
3Tf	U24Actf	AG057437Projectf	04S1Yearf		AISEN, PAUL S. Principal Investigator(s)/ Project Leader(s) PETERSEN, RONALD C Principal Investigator(s)/ Project Leader(s) SPERLING, REISA A. Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF SOUTHERN CALIFORNIA	2021	NIA	OD	$230,541	View View Similar Projects Similar Projectsf
Determining the neurodevelopmental cell type specific regulatory networks impacted in Down syndrome
1Tf	R03Actf	NS123969Projectf	01Yearf		ALDINGER, KIMBERLY ANNE Principal Investigator(s)/ Project Leader(s) WANG, DAIFENG Principal Investigator(s)/ Project Leader(s)	SEATTLE CHILDREN'S HOSPITAL	2021	NINDS	OD	$366,125	View View Similar Projects Similar Projectsf
Function of RUNX1 in diverse Down syndrome tissues
1Tf	R01Actf	HL156475Projectf	01Yearf		ALLEN, MARY A Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF COLORADO	2021	NHLBI	OD	$1,890,079	View View Similar Projects Similar Projectsf
Project 1: Biomarkers for Characterizing and Predicting AD in DS
5Tf	U19Actf	AG068054Projectf	02Yearf	7198	ANCES, BEAU M Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF PITTSBURGH AT PITTSBURGH	2021	NIA	NIA	$613,527	View View Similar Projects Similar Projectsf
Identification of optimum spectacle prescriptions for patients with Down syndrome
2Tf	R01Actf	EY024590Projectf	07A1Yearf		ANDERSON, HEATHER ANNE Principal Investigator(s)/ Project Leader(s)	OHIO STATE UNIVERSITY	2021	NEI	NEI	$406,254	View View Similar Projects Similar Projectsf
NICHD CONTRACT TO PROVIDE MAINTENANCE AND ENHANCEMENT OF 2 SYSTEMS OF RECORD- DOWN SYNDROME CONNECT AND PREGSOURCE ONLINE REGISTRIESMAINTENANCE OF RDPR AND CREA
75N94020F00276-P00001-0-1Tf					ANDRES, JILL Principal Investigator(s)/ Project Leader(s)		2021	NICHD	NICHD	$2,369,846	View View Similar Projects Similar Projectsf
CLINICAL PHARMACOKINETICS AND SAFETY TRIALS IN DOWN SYNDROME
275201800003I-P00002-759401900126-1Tf					BECKER, MARA Principal Investigator(s)/ Project Leader(s)	DUKE UNIVERSITY	2021	NICHD	NICHD	$1,500,903	View View Similar Projects Similar Projectsf
Human cortical development and neural plasticity altered by trisomy 21
1Tf	R01Actf	HD106197Projectf	01Yearf		BHATTACHARYYA, ANITA Principal Investigator(s)/ Project Leader(s) ZHANG, SU-CHUN Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF WISCONSIN-MADISON	2021	NICHD	OD	$7,005,920	View View Similar Projects Similar Projectsf
Uncovering the molecular mechanism of learning and memory with an emphasis on Down Syndrome
5Tf	R00Actf	GM126145Projectf	04Yearf		BHATTACHARYYA, MOITRAYEE Principal Investigator(s)/ Project Leader(s)	YALE UNIVERSITY	2021	NIGMS	NIGMS	$249,000	View View Similar Projects Similar Projectsf
Prenatal Treatment of Down Syndrome to Improve Brain Development and Neurocognition
1Tf	ZIAActf	HG200399Projectf	05Yearf		BIANCHI, DIANA Principal Investigator(s)/ Project Leader(s)	NATIONAL HUMAN GENOME RESEARCH INSTITUTE	2021	NHGRI	NICHD	$1,187,419	View View Similar Projects Similar Projectsf
Defining the Role of DNA Rereplication of Chromosome 21 in the Development and Pathophysiology of Down Syndrome
1Tf	R01Actf	AI155918Projectf	01Yearf		BLACK, JOSHUA CRANSTON Principal Investigator(s)/ Project Leader(s) SULLIVAN, KELLY D. Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF COLORADO DENVER	2021	NIAID	OD	$1,918,500	View View Similar Projects Similar Projectsf
Type I Interferon Dysregulation in Down Syndrome
3Tf	R01Actf	AI150300Projectf	01S2Yearf		BOGUNOVIC, DUSAN Principal Investigator(s)/ Project Leader(s)	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI	2021	NIAID	OD	$320,158	View View Similar Projects Similar Projectsf
A Longitudinal MRI Study Characterizing Very Early Brain Development in Infants with Down Syndrome
5Tf	R01Actf	HD088125Projectf	04Yearf		BOTTERON, KELLY N Principal Investigator(s)/ Project Leader(s)	WASHINGTON UNIVERSITY	2021	NICHD	OD	$2,360,348	View View Similar Projects Similar Projectsf
Role of astrocyte-secreted pleiotrophin in dendritic spine phenotypes in Down Syndrome
1Tf	F32Actf	NS117776Projectf	01A1Yearf		BRANDEBURA, ASHLEY N Principal Investigator(s)/ Project Leader(s)	SALK INSTITUTE FOR BIOLOGICAL STUDIES	2021	NINDS	NINDS	$66,390	View View Similar Projects Similar Projectsf
Depression, Stress, and Down Syndrome. A Multimethod Approach to Assessment
5Tf	K08Actf	HD092610Projectf	04Yearf		BROWN, RUTH C Principal Investigator(s)/ Project Leader(s)	VIRGINIA COMMONWEALTH UNIVERSITY	2021	NICHD	NICHD	$144,494	View View Similar Projects Similar Projectsf
Predictors of Speech Ability in Children with Down Syndrome
1Tf	R21Actf	DC019280Projectf	01A1Yearf		CAMARATA, STEPHEN MARK Principal Investigator(s)/ Project Leader(s) LENSE, MIRIAM Principal Investigator(s)/ Project Leader(s)	VANDERBILT UNIVERSITY MEDICAL CENTER	2021	NIDCD	OD	$483,161	View View Similar Projects Similar Projectsf
Administrative Core
1Tf	P50Actf	HD105353Projectf	01Yearf	8771	CHANG, QIANG Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF WISCONSIN-MADISON	2021	NICHD	NICHD	$144,937	View View Similar Projects Similar Projectsf
Evaluating ASD Symptomatology in Children with Down Syndrome
1Tf	R21Actf	HD106125Projectf	01Yearf		CHANNELL, MARIE MOORE Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN	2021	NICHD	OD	$440,823	View View Similar Projects Similar Projectsf
Core D: Neuroimaging Core
5Tf	U19Actf	AG068054Projectf	02Yearf	7194	CHRISTIAN, BRADLEY T Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF PITTSBURGH AT PITTSBURGH	2021	NIA	NIA	$4,251,051	View View Similar Projects Similar Projectsf
New Down syndrome brain organization revealed by single-cell genomics
1Tf	R56Actf	AG073965Projectf	01Yearf		CHUN, JEROLD Principal Investigator(s)/ Project Leader(s)	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	2021	NIA	NIA	$1,395,349	View View Similar Projects Similar Projectsf
Core B: Alzheimer's Disease Down Syndrome Outreach Recruitment and Education (ADDORE)
5Tf	U19Actf	AG068054Projectf	02Yearf	7192	COHEN, ANN D. Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF PITTSBURGH AT PITTSBURGH	2021	NIA	NIA	$1,489,370	View View Similar Projects Similar Projectsf
Medications for Obstructive Sleep Apnea to Improve Cognition in Children with Down Syndrome (MOSAIC DS)
3Tf	R61Actf	HL151254Projectf	02S1Yearf		COMBS, DANIEL Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF ARIZONA	2021	NHLBI	OD	$130,148	View View Similar Projects Similar Projectsf
Early Cognitive Decline in Down Syndrome
5Tf	R01Actf	HD098179Projectf	02Yearf		CONNERS, FRANCES A Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF ALABAMA IN TUSCALOOSA	2021	NICHD	OD	$603,809	View View Similar Projects Similar Projectsf
Early cognitive decline in Down syndrome - Supplement
3Tf	R01Actf	HD098179Projectf	02S1Yearf		CONNERS, FRANCES A Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF ALABAMA IN TUSCALOOSA	2021	NICHD	OD	$268,686	View View Similar Projects Similar Projectsf
Administrative Core
5Tf	P50Actf	HD103525Projectf	02Yearf	7823	CONSTANTINO, JOHN N. Principal Investigator(s)/ Project Leader(s)	WASHINGTON UNIVERSITY	2021	NICHD	NICHD	$147,150	View View Similar Projects Similar Projectsf
Mechanisms of leukemogenesis in Down syndrome
5Tf	R01Actf	CA101774Projectf	20Yearf		CRISPINO, JOHN D Principal Investigator(s)/ Project Leader(s)	ST. JUDE CHILDREN'S RESEARCH HOSPITAL	2021	NCI	NCI	$383,681	View View Similar Projects Similar Projectsf
Identifying the mechanisms of leukemia progression
1Tf	R35Actf	CA253096Projectf	01A1Yearf		CRISPINO, JOHN D Principal Investigator(s)/ Project Leader(s)	ST. JUDE CHILDREN'S RESEARCH HOSPITAL	2021	NCI	NCI	$1,077,000	View View Similar Projects Similar Projectsf
Core C: Translational Neurosciences Core
5Tf	P50Actf	HD103537Projectf	02Yearf	7967	CUTTING, LAURIE E Principal Investigator(s)/ Project Leader(s)	VANDERBILT UNIVERSITY MEDICAL CENTER	2021	NICHD	NICHD	$209,348	View View Similar Projects Similar Projectsf
Type I IFN signaling during lung development in Down Syndrome
1Tf	R01Actf	HL155104Projectf	01A1Yearf		DANOPOULOS, SOULA ATHANASIA Principal Investigator(s)/ Project Leader(s)	LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER	2021	NHLBI	OD	$1,805,958	View View Similar Projects Similar Projectsf
Clinical Translational Core
1Tf	P50Actf	HD105353Projectf	01Yearf	8772	DAWALT, LEANN SMITH Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF WISCONSIN-MADISON	2021	NICHD	NICHD	$240,751	View View Similar Projects Similar Projectsf
Project 2: Conformation and propagation of misfolded forms of tau and Abeta
5Tf	P01Actf	AG002132Projectf	40Yearf	6195	DEGRADO, WILLIAM Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF CALIFORNIA, SAN FRANCISCO	2021	NIA	NIA	$403,750	View View Similar Projects Similar Projectsf
Predoctoral Training Grant in Pharmacology INCLUDE Down Syndrome Supplement
3Tf	T32Actf	GM007635Projectf	43S1Yearf		DELL'ACQUA, MARK L Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF COLORADO DENVER	2021	NIGMS	OD	$111,960	View View Similar Projects Similar Projectsf
Heart and vascular responses across the lifespan in Ts65Dn mice, a model of Down syndrome
3Tf	R21Actf	HD099573Projectf	01A1S2Yearf		DERUISSEAU, LARA ROBERTS Principal Investigator(s)/ Project Leader(s)	SYRACUSE UNIVERSITY	2021	NICHD	OD	$112,500	View View Similar Projects Similar Projectsf
Heart and vascular responses across the lifespan in Ts65Dn mice, a model of Down syndrome
3Tf	R21Actf	HD099573Projectf	01A1S1Yearf		DERUISSEAU, LARA ROBERTS Principal Investigator(s)/ Project Leader(s)	SYRACUSE UNIVERSITY	2021	NICHD	NIA	$238,212	View View Similar Projects Similar Projectsf
Cognitive Outcome Measures in School Age Children with Down Syndrome
5Tf	R01Actf	HD093754Projectf	04Yearf		ESBENSEN, ANNA J. Principal Investigator(s)/ Project Leader(s)	CINCINNATI CHILDRENS HOSP MED CTR	2021	NICHD	NICHD	$529,166	View View Similar Projects Similar Projectsf
Evaluating Assessment and Medication Treatment of ADHD in Children with Down Syndrome
3Tf	R61Actf	HD100934Projectf	02S1Yearf		ESBENSEN, ANNA J. Principal Investigator(s)/ Project Leader(s) FROEHLICH, TANYA E. Principal Investigator(s)/ Project Leader(s)	CINCINNATI CHILDRENS HOSP MED CTR	2021	NICHD	OD	$164,639	View View Similar Projects Similar Projectsf
Administrative and Outreach Core
5Tf	U2CActf	HL156291Projectf	02Yearf	7301	ESPINOSA, JOAQUIN M. Principal Investigator(s)/ Project Leader(s)	CHILDREN'S HOSP OF PHILADELPHIA	2021	NHLBI	NHLBI	$706,334	View View Similar Projects Similar Projectsf
JAK Inhibition in Down Syndrome
3Tf	R61Actf	AR077495Projectf	02S1Yearf		ESPINOSA, JOAQUIN M. Principal Investigator(s)/ Project Leader(s) DUNNICK, CORY A Principal Investigator(s)/ Project Leader(s) NORRIS, DAVID A. Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF COLORADO DENVER	2021	NIAMS	OD	$612,030	View View Similar Projects Similar Projectsf
Function and dysfunction of REST in neurodegeneration
5Tf	K22Actf	NS107802Projectf	03Yearf		FERNANDEZ, MARTY Principal Investigator(s)/ Project Leader(s)	BRIGHAM AND WOMEN'S HOSPITAL	2021	NINDS	NINDS	$13,142	View View Similar Projects Similar Projectsf
Executive Function Outcome Measures for Young Children with Down Syndrome
5Tf	R01Actf	HD099150Projectf	03Yearf		FIDLER, DEBORAH J Principal Investigator(s)/ Project Leader(s)	COLORADO STATE UNIVERSITY	2021	NICHD	NICHD	$565,166	View View Similar Projects Similar Projectsf
Biosignatures of Executive Dysfunction in Down Syndrome
3Tf	R01Actf	HD099150Projectf	03S1Yearf		FIDLER, DEBORAH J Principal Investigator(s)/ Project Leader(s)	COLORADO STATE UNIVERSITY	2021	NICHD	OD	$875,785	View View Similar Projects Similar Projectsf
Cell and Network Disruptions and Associated Pathogenenesis in Tauopathy and Down Syndrome
5Tf	R01Actf	AG064579Projectf	02Yearf		FINKBEINER, STEVEN M Principal Investigator(s)/ Project Leader(s)	J. DAVID GLADSTONE INSTITUTES	2021	NIA	NIA	$641,436	View View Similar Projects Similar Projectsf
Genome Sequencing in support of the Gabriella Miller Kids First Pediatric Research Program
3Tf	U24Actf	HD090743Projectf	06S1Yearf		GABRIEL, STACEY Principal Investigator(s)/ Project Leader(s)	BROAD INSTITUTE, INC.	2021	NICHD	OD	$1,849,965	View View Similar Projects Similar Projectsf
Tongue maturation deficits in a mouse model of Down syndrome
1Tf	R01Actf	HD104640Projectf	01A1Yearf		GLASS, TIFFANY Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF WISCONSIN-MADISON	2021	NICHD	OD	$1,308,661	View View Similar Projects Similar Projectsf
Lens β-Amyloid Biomarker for Early Detection of Preclinical Alzheimer's Disease in the Framingham Study
1Tf	RF1Actf	AG072589Projectf	01Yearf		GOLDSTEIN, LEE E. Principal Investigator(s)/ Project Leader(s)	BOSTON UNIVERSITY MEDICAL CAMPUS	2021	NIA	NIA	$1,682,982	View View Similar Projects Similar Projectsf
Design And Development Of Experimental Therapeutics
1Tf	ZIAActf	AG000311Projectf	21Yearf		GREIG, NIGEL H. Principal Investigator(s)/ Project Leader(s)	NATIONAL INSTITUTE ON AGING	2021	NIA	NIA	$893,041	View View Similar Projects Similar Projectsf
Data Management Core
5Tf	U2CActf	HL156291Projectf	02Yearf	7302	GUINNEY, JUSTIN Principal Investigator(s)/ Project Leader(s)	CHILDREN'S HOSP OF PHILADELPHIA	2021	NHLBI	NHLBI	$1,421,930	View View Similar Projects Similar Projectsf
Emulating Immune Dysregulation by Trisomy 21 in a Multi-Organ-on-a-Chip System
1Tf	R01Actf	HL159494Projectf	01Yearf		HAJIPOURAN BENAM, KAMBEZ Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF PITTSBURGH AT PITTSBURGH	2021	NHLBI	OD	$2,101,852	View View Similar Projects Similar Projectsf
Core A: Administrative Core
5Tf	U19Actf	AG068054Projectf	02Yearf	7191	HANDEN, BENJAMIN L Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF PITTSBURGH AT PITTSBURGH	2021	NIA	NIA	$1,148,484	View View Similar Projects Similar Projectsf

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