Project Summary The University of Alabama at Birmingham (UAB)-University of California at San Diego (UCSD) O’Brien Center for Acute Kidney Injury (AKI) will oversee and manage the day-to-day conduct of the UAB-UCSD O’Brien Center, including the scientific, enrichment, fiscal, and communications operations and website maintenance. This Core will collaborate closely with the NIDDK, NCC, Steering Committee, and Consortium that will (i) Provide logistic, administrative, financial, and scientific oversight to the UAB-UCSD O’Brien Center Cores: assure the effectiveness, efficiency, and synergy of each of the two Biomedical Resource Cores and the Resource Development Core to enhance national outreach and impact.; (ii) Foster meaningful interactions and coordinate with the NCC and the Consortium to prioritize the development of shared, authenticated, and robust resources important for AKI-related research in addition to ensuring quality assurance/quality control (QA/QC) and rigor and reproducibility for the Core services.; (iii) Promote diversity of scientists pursuing AKI-related research; (iv) Promote opportunities that attract early-stage and new investigators to AKI research (v) Collaborate with the NCC to educate the community about AKI research and (vi) Optimize training and educational opportunities in kidney research for medical students through a Summer Student Training Program (SSTP. The Administrative Core will coordinate and integrate the diverse activities of the UAB-UCSD O’Brien Center, facilitate interactions and collaborations among the research base, ensure quality control, rigor and reproducibility of the core services and promote scientific development. The administrative structure with clear lines of authority has been developed to ensure that the goals and objectives of the Center are achieved. The Director and Associate Directors will make decisions and seek input as needed from the Steering Committee and the National Coordinating Center (NCC). The Administrative Core will oversee training and educational programs made available to the community to advance understanding of AKI-related research.

Project Narrative As per the RFA, not needed for individual components.