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20 Projects
Fiscal Year: Active Projects, 2022, 2021, 2020, 2019, 2018, 2017, 2016, 2015, 2014, 2013, 2012, 2011, 2010, 2009, 2008, 2007, 2006, 2005, 2004, 2003, 2002, 2001, 2000, 1999, 1998, 1997, 1996, 1995, 1994, 1993, 1992, 1991, 1990, 1989, 1988, 1987, 1986, 1985Organization: CASSAVA SCIENCES, INC

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TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
Opioid Antagonists with Morphine for Neuropathic Pain
1TfR41ActfNS047807Projectf01Yearf
BURNS, LINDSAY Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2004NINDS
NINDS
$100,000
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Food Effect study and drug supply scale-up for PTI-125
1TfR01ActfAG067972Projectf01A1Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2021NIA
NIA
$2,710,220
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IND- and NDA-enabling toxicology studies for PTI-125, a novel small molecule for Alzheimer's disease
1TfR44ActfAG050301Projectf01Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2015NIA
NIA
$225,000
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Extending clinical trial in AD patients from 1 to 3 months
3TfR44ActfAG060878Projectf01S1Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2018NIA
NIA
$374,500
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Multiple Ascending Dose clinical trial of PTI-125, a novel AD therapeutic candidate
1TfR44ActfAG060878Projectf01Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2018NIA
NIA
$260,585
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Additional bioanalytical, dose analysis and DSMB costs for PTI-125 development
3TfR44ActfAG056166Projectf02S1Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2017NIA
NIA
$141,748
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Increasing size of Phase 2b clinical trial to 60 patients
3TfR44ActfAG060878Projectf02S1Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2020NIA
NIA
$374,500
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IND- and NDA-enabling toxicology studies for PTI-125, a novel small molecule for Alzheimer's disease
4TfR44ActfAG050301Projectf02Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2016NIA
NIA
$1,500,000
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IND, FIH study and 3-month tox for PTI-125, a novel therapeutic for Alzheimer's disease
4TfR44ActfAG056166Projectf02Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2017NIA
NIA
$1,500,000
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Open-label extension of a 3-month blinded clinical trial of PTI-125
1TfR44ActfAG065152Projectf01Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2020NIA
NIA
$2,499,896
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Multiple Ascending Dose clinical trial of PTI-125, a novel AD therapeutic candidate
4TfR44ActfAG060878Projectf02Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2019NIA
NIA
$2,896,561
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IND, FIH study and 3-month tox for PTI-125, a novel therapeutic for Alzheimer's disease
1TfR44ActfAG056166Projectf01Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2017NIA
NIA
$225,000
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Solid oral dosage form and chronic tox for PTI-125
2TfR44ActfAG056166Projectf03Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2018NIA
NIA
$2,896,320
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Additional costs related to formulation, chronic tox and general development of PTI-125
3TfR44ActfAG056166Projectf03S1Yearf
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2018NIA
NIA
$350,000
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Preformulation and formulation development of Fenrock, an Abuse-resistant Fentanyl Transdermal Patch
1TfR44ActfDA042639Projectf01A1Yearf
KUCERA, SHAWN Principal Investigator(s)/ Project Leader(s)
ZAMLOOT, MICHAEL SAMUEL Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2017NIDA
NIDA
$349,947
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Preformulation and formulation development of Fenrock, an Abuse-resistant Fentanyl Transdermal Patch
4TfR44ActfDA042639Projectf02Yearf
KUCERA, SHAWN Principal Investigator(s)/ Project Leader(s)
ZAMLOOT, MICHAEL SAMUEL Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2019NIDA
NIDA
$1,879,039
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Development of PTI-125-DX, a blood-based diagnostic for Alzheimer's disease
5TfR44ActfAG057329Projectf03Yearf
THORNTON, GEORGE BEN Principal Investigator(s)/ Project Leader(s)
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
WANG, HOAU-YAN Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2020NIA
NIA
$450,142
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Development of PTI-125-DX, a blood-based diagnostic for Alzheimer's disease
4TfR44ActfAG057329Projectf02Yearf
THORNTON, GEORGE BEN Principal Investigator(s)/ Project Leader(s)
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
WANG, HOAU-YAN Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2019NIA
NIA
$1,109,748
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Development of PTI-125-DX, a blood-based diagnostic for Alzheimer's disease
1TfR42ActfAG057329Projectf01Yearf
THORNTON, GEORGE BEN Principal Investigator(s)/ Project Leader(s)
BURNS, LINDSAY H Principal Investigator(s)/ Project Leader(s)
WANG, HOAU-YAN Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2017NIA
NIA
$295,343
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Abuse-deterrent sustained-release hydromorphone
1TfR43ActfDA019739Projectf01A1Yearf
ZAMLOOT, MICHAEL SAMUEL Principal Investigator(s)/ Project Leader(s)
CASSAVA SCIENCES, INC2006NIDA
NIDA
$100,000
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