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55 Projects
Fiscal Year: 2023Exclude Subprojects: YesProject Number/Application ID: 10550177, 10550251, 10551234, 10557093, 10557915, 10557916, 10570830, 10572539, 10572855, 10585386, 10610878, 10612857, 10626830, 10627916, 10629262, 10638072, 10643544, 10645980, 10652025, 10652447, 10653940, 10654027, 10654818, 10656196, 10657551, 10657647, 10657681, 10657750, 10666294, 10666637, 10668178, 10679055, 10679088, 10687972, 10694940, 10698090, 10701663, 10701670, 10703360, 10710055, 10733155, 10733164, 10733165, 10733815, 10740240, 10761821, 10773765, 10792416, 10833813, 10837914, 10840531, 10846199, 10846272, 10929710, 10556351

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TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
EDGE CMT: Genomic characterization of mammalian adaptation to frugivory
5TfR01ActfHG012396Projectf02Yearf
AHITUV, NADAV Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO2023NHGRI
NHGRI
$472,161
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Mapping dynamic functional networks across environments and backgrounds
5TfR01ActfHG005853Projectf12Yearf
ANDREWS, BRENDA JEAN Principal Investigator(s)/ Project Leader(s)
BOONE, CHARLES Principal Investigator(s)/ Project Leader(s)
MYERS, CHAD L Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF TORONTO2023NHGRI
NHGRI
$493,928
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Causal Effect Estimation of Regulatory Molecules
5TfR00ActfHG011367Projectf04Yearf
ASIAEETAHERI, AMIR Principal Investigator(s)/ Project Leader(s)
VANDERBILT UNIVERSITY MEDICAL CENTER2023NHGRI
NHGRI
$240,563
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Quantitative and function analysis platform for repetitive genes and gene isoforms in pluripotency regulation and differentiations
7TfR01ActfHG011469Projectf03Yearf
AU, KIN FAI Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF MICHIGAN AT ANN ARBOR2023NHGRI
NHGRI
$685,178
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Machine learning methods for interpreting spatial multi-omics data
1TfR01ActfHG012875Projectf01Yearf
AZIZI, ELHAM Principal Investigator(s)/ Project Leader(s)
COLUMBIA UNIV NEW YORK MORNINGSIDE2023NHGRI
NHGRI
$452,625
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Computational toolbox for spatial transcriptomic analysis of complex tissues
1TfR21ActfHG012639Projectf01A1Yearf
AZIZI, ELHAM Principal Investigator(s)/ Project Leader(s)
COLUMBIA UNIV NEW YORK MORNINGSIDE2023NHGRI
NHGRI
$435,475
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CEGS: Center for Synthetic Regulatory Genomics - Renewal
2TfRM1ActfHG009491Projectf06Yearf
BOEKE, JEF D Principal Investigator(s)/ Project Leader(s)
NEW YORK UNIVERSITY SCHOOL OF MEDICINE2023NHGRI
NHGRI
$2,500,000
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Developing new computational tools for spatial transcriptomics data
5TfR01ActfHG011883Projectf03Yearf
CHEN, MENGJIE Principal Investigator(s)/ Project Leader(s)
ZHOU, XIANG Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF CHICAGO2023NHGRI
NHGRI
$381,266
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Statistical Power Calculation Framework for Spatially Resolved Transcriptomics Experiments
5TfR21ActfHG012482Projectf02Yearf
CHUNG, DONGJUN Principal Investigator(s)/ Project Leader(s)
MA, QIN Principal Investigator(s)/ Project Leader(s)
OHIO STATE UNIVERSITY2023NHGRI
NHGRI
$229,983
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Title: Functional Annotation of Genomes via Phenotypic Convergence within Large Multi-species Alignments
2TfR01ActfHG009299Projectf06A1Yearf
CLARK, NATHANIEL L Principal Investigator(s)/ Project Leader(s)
CHIKINA, MARIA D Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF PITTSBURGH AT PITTSBURGH2023NHGRI
NHGRI
$529,944
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Pan-disease characterization of DNA methylation dysregulation
4TfR00ActfHG011658Projectf03Yearf
CLEMENT, KENDELL Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF UTAH2023NHGRI
NHGRI
$249,000
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Domain adaptation approaches to unify established and emerging sequencing technologies
1TfK99ActfHG012945Projectf01Yearf
DAVIDSON, NATALIE ROSE Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF COLORADO DENVER2023NHGRI
NHGRI
$134,389
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Statistical and high-throughput models of enhancer function and evolution
3TfR01ActfHG011485Projectf03S2Yearf
EDWARDS, SCOTT V. Principal Investigator(s)/ Project Leader(s)
FARLEY, EMMA KIRSTEN Principal Investigator(s)/ Project Leader(s)
LIU, JUN S Principal Investigator(s)/ Project Leader(s)
SACKTON, TIMOTHY Principal Investigator(s)/ Project Leader(s)
TABIN, CLIFFORD J. Principal Investigator(s)/ Project Leader(s)
HARVARD UNIVERSITY2023NHGRI
NHGRI
$26,310
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Statistical and high-throughput models of enhancer function and evolution
3TfR01ActfHG011485Projectf03S1Yearf
EDWARDS, SCOTT V. Principal Investigator(s)/ Project Leader(s)
FARLEY, EMMA KIRSTEN Principal Investigator(s)/ Project Leader(s)
LIU, JUN S Principal Investigator(s)/ Project Leader(s)
SACKTON, TIMOTHY Principal Investigator(s)/ Project Leader(s)
TABIN, CLIFFORD J. Principal Investigator(s)/ Project Leader(s)
HARVARD UNIVERSITY2023NHGRI
NHGRI
$59,045
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Statistical and high-throughput models of enhancer function and evolution
5TfR01ActfHG011485Projectf03Yearf
EDWARDS, SCOTT V. Principal Investigator(s)/ Project Leader(s)
FARLEY, EMMA KIRSTEN Principal Investigator(s)/ Project Leader(s)
LIU, JUN S Principal Investigator(s)/ Project Leader(s)
SACKTON, TIMOTHY Principal Investigator(s)/ Project Leader(s)
TABIN, CLIFFORD J. Principal Investigator(s)/ Project Leader(s)
HARVARD UNIVERSITY2023NHGRI
NHGRI
$563,968
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MorPhiC: Constructing a Catalog of Cellular Programs to Identify and Annotate Human Disease Genes
1TfU01ActfHG013176Projectf01Yearf
ENGREITZ, JESSE M Principal Investigator(s)/ Project Leader(s)
KUNDAJE, ANSHUL Principal Investigator(s)/ Project Leader(s)
STANFORD UNIVERSITY2023NHGRI
NHGRI
$492,004
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Functional Genomics: A Phenome-wide Survey
5TfR35ActfHG010718Projectf05Yearf
GAMAZON, ERIC R Principal Investigator(s)/ Project Leader(s)
VANDERBILT UNIVERSITY MEDICAL CENTER2023NHGRI
NHGRI
$440,795
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An interactive tool for in-depth and reproducible analysis of RNA-seq data
5TfR01ActfHG010805Projectf04Yearf
GE, XIJIN Principal Investigator(s)/ Project Leader(s)
SOUTH DAKOTA STATE UNIVERSITY2023NHGRI
NHGRI
$176,975
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Precision mapping of regulatory causal variants by expression CROPseq
5TfR01ActfHG011459Projectf03Yearf
GIBSON, GREGORY C Principal Investigator(s)/ Project Leader(s)
BAO, GANG Principal Investigator(s)/ Project Leader(s)
GEORGIA INSTITUTE OF TECHNOLOGY2023NHGRI
NHGRI
$696,862
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Computational Methods for Inferring Single-cell DNA Methylation and its Spatial Landscape
5TfR00ActfHG011468Projectf04Yearf
HOU, WENPIN Principal Investigator(s)/ Project Leader(s)
COLUMBIA UNIVERSITY HEALTH SCIENCES2023NHGRI
NHGRI
$249,000
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Model-based methods for single cell chromatin interactomic data
5TfR35ActfHG011922Projectf03Yearf
HU, MING Principal Investigator(s)/ Project Leader(s)
CLEVELAND CLINIC LERNER COM-CWRU2023NHGRI
NHGRI
$480,583
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Genomic control of gene regulatory networks governing early human lineagedecisions
3TfU01ActfHG012051Projectf03S2Yearf
HUANGFU, DANWEI Principal Investigator(s)/ Project Leader(s)
BEER, MICHAEL A Principal Investigator(s)/ Project Leader(s)
HADJANTONAKIS, ANNA-KATERINA Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2023NHGRI
NHGRI
$103,202
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Genomic control of gene regulatory networks governing early human lineagedecisions
3TfU01ActfHG012051Projectf03S1Yearf
HUANGFU, DANWEI Principal Investigator(s)/ Project Leader(s)
BEER, MICHAEL A Principal Investigator(s)/ Project Leader(s)
HADJANTONAKIS, ANNA-KATERINA Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2023NHGRI
NHGRI
$97,511
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Center for Genomic Information Encoded by RNA Nucleotide Modifications
5TfRM1ActfHG011563Projectf03Yearf
JAFFREY, SAMIE R Principal Investigator(s)/ Project Leader(s)
MEYER, KATHRYN D Principal Investigator(s)/ Project Leader(s)
WEILL MEDICAL COLL OF CORNELL UNIV2023NHGRI
NHGRI
$2,058,511
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Statistical methods for co-expression network analysis of population-scale scRNA-seq data
1TfR21ActfHG012881Projectf01A1Yearf
KELES, SUNDUZ Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF WISCONSIN-MADISON2023NHGRI
NHGRI
$407,645
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Roles of allele-specific chromatin interactions in transcription regulation during development
4TfR00ActfHG011542Projectf03Yearf
KIM, MINJI Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF MICHIGAN AT ANN ARBOR2023NHGRI
NHGRI
$245,921
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Interpretable Computational Models of Functional Genomics Data
5TfR01ActfHG012131Projectf02Yearf
KOO, PETER K Principal Investigator(s)/ Project Leader(s)
COLD SPRING HARBOR LABORATORY2023NHGRI
NHGRI
$432,000
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Integrative analysis of spatial transcriptomics with histology images and single cells
1TfR01ActfHG013185Projectf01A1Yearf
LI, MINGYAO Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF PENNSYLVANIA2023NHGRI
NHGRI
$546,646
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Multi-omic phenotyping of human transcriptional regulators
1TfU01ActfHG013175Projectf01Yearf
LI, SHENG Principal Investigator(s)/ Project Leader(s)
WHITE, BRIAN S Principal Investigator(s)/ Project Leader(s)
JACKSON LABORATORY2023NHGRI
NHGRI
$576,097
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Modeling Functional Elements using CRISPR Screening
5TfR01ActfHG010753Projectf05Yearf
LI, WEI Principal Investigator(s)/ Project Leader(s)
CHILDREN'S RESEARCH INSTITUTE2023NHGRI
NHGRI
$446,250
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Modeling Heterogenous Outcomes in Functional Genetic Screens Using Single-cell Genomics as Readouts
3TfR01ActfHG010753Projectf05S1Yearf
LI, WEI Principal Investigator(s)/ Project Leader(s)
CHILDREN'S RESEARCH INSTITUTE2023NHGRI
NHGRI
$268,752
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Joint analysis of 3D chromatin organization and 1D epigenome
5TfR35ActfHG011279Projectf04Yearf
LIU, JIE Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF MICHIGAN AT ANN ARBOR2023NHGRI
NHGRI
$425,259
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From a Long List to Causal Variants: High-Throughput Gene Regulatory Assays in Developing Tissues
5TfR35ActfHG011332Projectf04Yearf
LOWE, CRAIG BARRETT Principal Investigator(s)/ Project Leader(s)
DUKE UNIVERSITY2023NHGRI
NHGRI
$458,859
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Computational methods for studying single-cell 3D genome
5TfR01ActfHG012303Projectf02Yearf
MA, JIAN Principal Investigator(s)/ Project Leader(s)
DUAN, ZHIJUN Principal Investigator(s)/ Project Leader(s)
CARNEGIE-MELLON UNIVERSITY2023NHGRI
NHGRI
$544,905
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Elucidation of the organizing principles of the regulatory genome through large-scale data integration
5TfR35ActfHG011317Projectf04Yearf
MEULEMAN, WOUTER Principal Investigator(s)/ Project Leader(s)
ALTIUS INSTITUTE FOR BIOMEDICAL SCIENCES2023NHGRI
NHGRI
$369,847
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Deep tensor genomic imputation
5TfR01ActfHG011466Projectf03Yearf
NOBLE, WILLIAM STAFFORD Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF WASHINGTON2023NHGRI
NHGRI
$383,797
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A kinetic framework to map the genetic determinants of alternative RNA isoform expression
1TfR01ActfHG012967Projectf01Yearf
PAI, ATHMA A Principal Investigator(s)/ Project Leader(s)
ENGELHARDT, BARBARA Principal Investigator(s)/ Project Leader(s)
UNIV OF MASSACHUSETTS MED SCH WORCESTER2023NHGRI
NHGRI
$770,641
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Integration of functional data and GWAS to elucidate genetic basis of diseases
5TfR01ActfHG008140Projectf07Yearf
PRITCHARD, JONATHAN K Principal Investigator(s)/ Project Leader(s)
STANFORD UNIVERSITY2023NHGRI
NHGRI
$712,928
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High-throughput detection of transcriptomic and epitranscriptomic variation and kinetics using MarathonRT
5TfR01ActfHG011868Projectf03Yearf
PYLE, ANNA MARIE Principal Investigator(s)/ Project Leader(s)
GRAVELEY, BRENTON R. Principal Investigator(s)/ Project Leader(s)
YALE UNIVERSITY2023NHGRI
NHGRI
$951,769
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Predictive modeling of mammalian cell fate transitions over time and space with single-cell genomics
1TfK99ActfHG012887Projectf01Yearf
QIU, XIAOJIE Principal Investigator(s)/ Project Leader(s)
WHITEHEAD INSTITUTE FOR BIOMEDICAL RES2023NHGRI
NHGRI
$85,045
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Comprehensive Characterization of Adaptive Regulatory Variation Linked to Human Disease
5TfR00ActfHG010669Projectf05Yearf
REILLY, STEVEN K. Principal Investigator(s)/ Project Leader(s)
YALE UNIVERSITY2023NHGRI
NHGRI
$242,227
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Leveraging multi-species single cell omic datasets to study the evolution of cell type-specific gene regulatory networks
5TfR01ActfHG012349Projectf02Yearf
ROY, SUSHMITA Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF WISCONSIN-MADISON2023NHGRI
NHGRI
$464,755
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Computational Methods for Assembling Multiple RNA-seq Samples
5TfR01ActfHG011065Projectf03Yearf
SHAO, MINGFU Principal Investigator(s)/ Project Leader(s)
PENNSYLVANIA STATE UNIVERSITY, THE2023NHGRI
NHGRI
$369,648
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Novel computational approaches to characterize the effects of rare functional outlier variants on cis- and trans-regulatory disease processes
5TfR21ActfHG012422Projectf02Yearf
SMAIL, CRAIG Principal Investigator(s)/ Project Leader(s)
CHILDREN'S MERCY HOSP (KANSAS CITY, MO)2023NHGRI
NHGRI
$234,000
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Function-based exploration of genetic variation at genome-scale
5TfR01ActfHG011664Projectf02Yearf
STEINMETZ, LARS M Principal Investigator(s)/ Project Leader(s)
STANFORD UNIVERSITY2023NHGRI
NHGRI
$708,204
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Statistical Methods for Inferring Gene-Phenotype Associations Using Omic Data from Gene Knockout and Human Phenotype Studies
1TfU01ActfHG013177Projectf01Yearf
SUN, WEI Principal Investigator(s)/ Project Leader(s)
HSU, LI Principal Investigator(s)/ Project Leader(s)
SHOJAIE, ALI Principal Investigator(s)/ Project Leader(s)
FRED HUTCHINSON CANCER CENTER2023NHGRI
NHGRI
$555,678
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Generating a full-length reference transcriptome for human protein-coding genes
5TfU24ActfHG011451Projectf02Yearf
VIDAL, MARC Principal Investigator(s)/ Project Leader(s)
HILL, DAVID E. Principal Investigator(s)/ Project Leader(s)
MARTIN, FERGAL JAMES Principal Investigator(s)/ Project Leader(s)
DANA-FARBER CANCER INST2023NHGRI
NHGRI
$663,518
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Novel bioinformatics methods to detect DNA and RNA modifications using Nanopore long-read sequencing
1TfR01ActfHG013359Projectf01Yearf
WANG, KAI Principal Investigator(s)/ Project Leader(s)
CHILDREN'S HOSP OF PHILADELPHIA2023NHGRI
NHGRI
$709,603
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Identification and analysis of non-coding loci critical for cell viability and chromatin organization
5TfR01ActfHG009626Projectf06Yearf
WANG, WEI Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF CALIFORNIA, SAN DIEGO2023NHGRI
NHGRI
$597,384
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Unsupervised Statistical Methods for Data-driven Analyses in Spatially Resolved Transcriptomics Data
5TfK99ActfHG012229Projectf02Yearf
WEBER, LUKAS MARTIN Principal Investigator(s)/ Project Leader(s)
JOHNS HOPKINS UNIVERSITY2023NHGRI
NHGRI
$46,759
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