Project Summary Genetics and genomics have become increasingly important in research and medicine. Moreover, with core tenets valuing variation, genetics and genomics must lead in the appreciation and incorporation of diversity into biomedical research. In doing so, we must also correct the demographic makeup of the research workforce, to more nearly represent the diversity of the general population. We endorse that all levels of the research and clinical workforce should have fundamental knowledge and skills in genetics and genomics and understand its role in public health. These steps are necessary to reduce health inequities and rebuild trust with historically underserved populations so that we may boost their enrollment in research and incorporate genetics and genomics into their healthcare. To achieve this goal, we will develop genomics educational modules (GEMs) for the entry-level medical and research workforce. These modules will build on our recent experience developing and delivering an online Genetic Assistant Training Program (GATP) to over 300 successful graduates. Using the experience of our graduates of the GATP and input from a carefully selected Advisory Committee of educators and employers, we will develop GEM content, best practices, and workforce needs. The content of these modules will be devoted to the following topics: Genetics & Genomics of Cardiovascular Conditions, Cancer, Reproductive Healthcare, Newborn Health, Child Health, Laboratory Genomics, and Responsible Conduct of Research. Educational content will include slide decks, recorded lectures, lab protocols, and assessments. We will incorporate animations in education modules to boost engagement and we will build on the educational principles of adult learning theory and universal design for learning to maximize accessibility. We will develop, pilot, and refine existing and new GEMs targeted to students in entry-level training programs at three Baltimore City partner sites that offer courses for laboratory associates, medical assistants, and community health workers. These sites include Baltimore’s BioTechnical Institute (BTI), the Community College of Baltimore County (CCBC) Medical Assistant training program, and the Baltimore City Community College (BCCC) Healthcare Workforce Development Program. These sites were selected given their dedication to the community, and their support and enrollment of students that come from demographics that are underrepresented in science. Ultimately, we will disseminate the GEMs at no cost on an easily accessible website with the capability to be downloaded and used both nationally and internationally.

Project Narrative Genetics and genomics are expanding into biomedical research and healthcare, so it is essential that all levels of the research and clinical workforce have some knowledge regarding these topics to ensure that this expansion is done in an inclusive and ethical way. Given the relatively high prevalence of many genetic conditions (e.g., familial hypercholesterolemia, breast cancer, sickle cell disease, etc.), establishing a knowledge-base for the wide applicability of genetics and genomics to the general public will facilitate integration of these topics into research to benefit health outcomes. We will create and freely share genomics learning modules (GEMs) enabling entry-level training and certificate programs to add genetics and genomics education to their curricula so that their graduates will be able to use, apply and disseminate this knowledge.