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820 Projects
Fiscal Year: Active ProjectsAgency/Institute/Center: Nat'l Inst of Allergy and Infectious Diseases (NIAID)Funding: YesText Search: Tuberculosis (and)Limit to: Project Title, Project Terms, Project Abstracts
TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
KwaZulu-Natal Clinical Trials Unit
5TfUM1ActfAI069469Projectf19YearfCENTRE/AIDS PROGRAMME/RES/SOUTH AFRICA2025NIAID
NIAID
$1,043,933
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Chemical genetics of M. tuberculosis DosRST signaling and persistence
5TfR01ActfAI150855Projectf05YearfMICHIGAN STATE UNIVERSITY2024NIAID
NIAID
$359,866
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Defining the antibacterial activities of ozonides
5TfR03ActfAI182633Projectf02YearfMICHIGAN STATE UNIVERSITY2025NIAID
NIAID
$77,931
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Chemical biology studies of MmpL3 inhibition and resistance in mycobacteria
5TfR01ActfAI173285Projectf02YearfMICHIGAN STATE UNIVERSITY2024NIAID
NIAID
$747,825
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Chicago Clinical Trials Unit
5TfUM1ActfAI069471Projectf19YearfNORTHWESTERN UNIVERSITY AT CHICAGO2025NIAID
NIAID
$507,116
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Characteristics and protective efficacy of human antibodies against M. tuberculosis
3TfR01ActfAI146329Projectf05S1YearfALBERT EINSTEIN COLLEGE OF MEDICINE2023NIAID
NIAID
$44,856
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Characteristics and protective efficacy of human antibodies against M. tuberculosis
5TfR01ActfAI146329Projectf05YearfALBERT EINSTEIN COLLEGE OF MEDICINE2023NIAID
NIAID
$716,093
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T cell recognition of the MR1 presented microbial metabolome
5TfR01ActfAI147954Projectf05YearfUNIVERSITY OF CHICAGO2023NIAID
NIAID
$1,836,140
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Role of Lung Repair and Regeneration Pathways in Tuberculosis
1TfR21ActfAI174034Projectf01A1YearfUNIVERSITY OF CHICAGO2024NIAID
NIAID
$246,000
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Core 2: BSL-3 Practices Core
5TfUC7ActfAI180254Projectf02Yearf9672DUKE UNIVERSITY2024NIAID
NIAID
$895,157
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Lesion-centric optimization of multidrug therapies for tuberculosis
5TfR01ActfAI150684Projectf05YearfTUFTS UNIVERSITY BOSTON2024NIAID
NIAID
$818,294
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Single-cell factors of tuberculosis drug tolerance during adaptation to environmental stressors
5TfR01ActfAI143611Projectf04YearfTUFTS UNIVERSITY BOSTON2023NIAID
NIAID
$705,360
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International Maternal, Adolescent and Pediatric Therapeutics Clinical Trials Network
5TfUM1ActfAI106716Projectf13YearfUNIVERSITY OF CALIFORNIA LOS ANGELES2025NIAID
NIAID
NICHD
$1,749,062
$1,000,000
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AIDS Clinical Trial Group Laboratory Center
5TfUM1ActfAI106701Projectf12YearfUNIVERSITY OF CALIFORNIA LOS ANGELES2025NIAID
NIAID
$6,250,000
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Biocontainment Research support services core
5TfUC7ActfAI180261Projectf02Yearf9872GEORGE MASON UNIVERSITY2024NIAID
NIAID
$755,531
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Metabolic Syndrome Outcomes Among Patients with Tuberculosis in Tanzania
1TfK23ActfAI187709Projectf01YearfMEDICAL UNIVERSITY OF SOUTH CAROLINA2025NIAID
NIAID
$201,549
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Bacteria and Host in TB Transmission
7TfR01ActfAI147345Projectf04YearfRUTGERS BIOMEDICAL AND HEALTH SCIENCES2023NIAID
NIAID
$1,697,099
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Development of novel anti-TB drugs that inhibit cell wall biosynthesis and respiration
5TfU19ActfAI142731Projectf05Yearf7613HACKENSACK UNIVERSITY MEDICAL CENTER2023NIAID
NIAID
$629,538
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Resources, Workforce Development, and Animal Models for the Rutgers RBL
5TfUC7ActfAI180307Projectf02YearfRUTGERS BIOMEDICAL AND HEALTH SCIENCES2024NIAID
NIAID
$4,189,403
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Point of care detection of fluroquinolone, bedaquiline and linezolid resistant Mycobacterium tuberculosis for rapid treatment decisions.
5TfR01ActfAI182257Projectf02YearfRUTGERS BIOMEDICAL AND HEALTH SCIENCES2025NIAID
NIAID
$758,976
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Nanoreactor beads for POC TB resistance testing
5TfR01ActfAI179961Projectf02YearfRUTGERS BIOMEDICAL AND HEALTH SCIENCES2025NIAID
NIAID
$686,998
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Bacterial and Host Heterogeneity in TB latency, persistence and progression
5TfU19ActfAI162598Projectf04YearfRUTGERS BIOMEDICAL AND HEALTH SCIENCES2024NIAID
NIAID
$2,749,420
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MYCOBACTERIUM TUBERCULOSIS PROTEOME-WIDE EPITOPE DISCOVERY AND HOST TRANSCRIPTOME-WIDE T CELL PHENOTYPING IN HIGH DISEASE BURDEN POPULATIONS
75N93024C00054-0-9999-1TfTRANSLATIONAL GENOMICS RESEARCH INST2024NIAID
NIAID
$1,504,937
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A new method for active tuberculosis case finding
5TfR01ActfAI176581Projectf02YearfMUHIMBILI UNIVERSITY/ ALLIED HLTH SCIS2024NIAID
NIAID
$134,465
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Central Africa International Epidemiology databases to Evaluate AIDS
5TfU01ActfAI096299Projectf16YearfALBERT EINSTEIN COLLEGE OF MEDICINE2024NIAID
NIAAA
NIAID
NCI
NIDA
NIDDK
NICHD
NHLBI
FIC
$68,542
$1,421,690
$253,604
$117,206
$68,542
$750,000
$137,083
$83,333
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Flow Cytometry Workshops in Africa
1TfR13ActfAI189265Projectf01YearfFRED HUTCHINSON CANCER CENTER2025NIAID
NIAID
$25,000
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Mentoring patient-oriented translational research in tuberculosis
1TfK24ActfAI182647Projectf01YearfSTANFORD UNIVERSITY2024NIAID
NIAID
$171,924
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Strategies for tuberculosis control in prisons
5TfR01ActfAI130058Projectf08YearfSTANFORD UNIVERSITY2025NIAID
NIAID
$634,909
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Point-of-care pharmacogenomic testing to optimize isoniazid dosing for tuberculosis prevention
5TfR21ActfAI172182Projectf02YearfSTANFORD UNIVERSITY2023NIAID
NIAID
$189,443
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Immunometabolic signatures of BCG-induced neonatal trained immunity
5TfK08ActfAI168487Projectf02YearfBETH ISRAEL DEACONESS MEDICAL CENTER2024NIAID
NIAID
$175,572
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Immunoproteomic mechanisms of human macrophage resistance to Mycobacterium tuberculosis infection
5TfK08ActfAI163381Projectf04YearfUNIVERSITY OF WASHINGTON2024NIAID
NIAID
$63,920
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Combining B. thuringiensis crystal proteins with small molecule anthelmintics to combat parasitic nematode resistance
1TfR01ActfAI182355Projectf01A1YearfUNIV OF MASSACHUSETTS MED SCH WORCESTER2025NIAID
NIAID
$769,201
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Development of peptide nucleic acid antibiotics
5TfR42ActfAI114114Projectf05YearfNUBAD, LLC2024NIAID
NIAID
$998,585
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Development of an automated HIV self-testing assay
4TfR33ActfAI154643Projectf04YearfFLORIDA ATLANTIC UNIVERSITY2025NIAID
NIAID
$656,450
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Discovery of Phospopantetheinyl Transferse Inhibitors Against Mycobacterium tuberculosis
5TfR01ActfAI155510Projectf04YearfUNIV OF NORTH CAROLINA CHAPEL HILL2024NIAID
NIAID
$770,597
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Inflammation and Fibrosis in Pulmonary TB: the INFIN-TB Study
5TfR01ActfAI166988Projectf03YearfEMORY UNIVERSITY2024NIAID
NIAID
$1,079,424
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Mechanism of action of Dapsone in Mycobacterium leprae
5TfR21ActfAI175596Projectf02YearfCOLORADO STATE UNIVERSITY2024NIAID
NIAID
$231,000
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Monitoring Treatment Efficacy in Leprosy
5TfR21ActfAI171254Projectf02YearfCOLORADO STATE UNIVERSITY2023NIAID
NIAID
$171,012
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Determining the performance and accuracy of SILVAMP TB LAM and cost-effectiveness of diagnostic testing for TB meningitis
5TfR01ActfAI170158Projectf04YearfUNIVERSITY OF MINNESOTA2024NIAID
NIAID
$732,368
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A novel c-di-AMP-based recombinant BCG vaccine
5TfR21ActfAI169111Projectf02YearfALBANY MEDICAL COLLEGE2024NIAID
NIAID
$203,750
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Precision immunoprofiling to reveal diagnostic biomarkers of latent TB infection
5TfR01ActfAI141591Projectf04YearfUNIVERSITY OF MICHIGAN AT ANN ARBOR2022NIAID
NIAID
$719,615
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Combined Use of Statistical Process Control and Whole Genome Sequencing to Detect and Investigate Nontuberculous Mycobacterial Clusters and Outbreaks
5TfK08ActfAI163462Projectf04YearfDUKE UNIVERSITY2024NIAID
NIAID
$188,377
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A systems analysis of drug tolerance in Mycobacterium tuberculosis
5TfR01ActfAI128215Projectf08YearfINSTITUTE FOR SYSTEMS BIOLOGY2024NIAID
NIAID
$868,716
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A systems approach to manipulate microbial adaptation to structured environments
5TfR01ActfAI141953Projectf05YearfINSTITUTE FOR SYSTEMS BIOLOGY2023NIAID
NIAID
$871,106
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The role of Chlamydia trachomatis specific HLA-E restricted CD8 T cell responses in clearance of infection
5TfR21ActfAI175809Projectf02YearfUNIVERSITY OF ALABAMA AT BIRMINGHAM2024NIAID
NIAID
$185,625
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SARS-CoV-2 infection of non-human primates
1TfZIAActfAI001294Projectf05YearfNATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES2024NIAID
NIAID
$397,520
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Immune Regulation in Mycobacterial and Fungal Infections
1TfZIAActfAI001171Projectf13YearfNATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES2024NIAID
NIAID
$1,328,731
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Elucidating the path to type I IFNs in TB infection
5TfR01ActfAI150762Projectf04YearfMASSACHUSETTS GENERAL HOSPITAL2024NIAID
NIAID
$693,073
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Elucidating the path to type I IFNs in TB infection
3TfR01ActfAI150762Projectf04S1YearfMASSACHUSETTS GENERAL HOSPITAL2024NIAID
NIAID
$82,895
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Capturing spatial patterns of new M. tuberculosis infection in Kampala, Uganda
5TfR01ActfAI147319Projectf06YearfCASE WESTERN RESERVE UNIVERSITY2024NIAID
NIAID
$793,932
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