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395 Projects
Fiscal Year: Active ProjectsActivity Code: DP2
TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
Revealing the Biophysics of the Germinal Center Microenvironment
5TfDP2ActfAI154410Projectf04YearfUNIVERSITY OF TEXAS MED BR GALVESTON2025NIAID
NIAID
$480,000
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Lighting up the brain: Optogenetic tools to record, trace, and manipulate brain circuits at cellular resolution
4TfDP2ActfMH129956Projectf02YearfBROWN UNIVERSITY2024NIMH
NIMH
$957,000
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Using mouse pain scales to discover unusual pain sensitivity and new pain targets
1TfDP2ActfNS130454Projectf01YearfCOLUMBIA UNIV NEW YORK MORNINGSIDE2022NINDS
NINDS
$2,467,500
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Innovations and mechanisms in tumor subcellular metabolism
4TfDP2ActfCA271386Projectf02YearfSTANFORD UNIVERSITY2024NCI
OD
$944,400
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Nuclear magnetic resonance microscope based on diamond quantum sensors
1TfDP2ActfGM140921Projectf01YearfUNIVERSITY OF NEW MEXICO2020NIGMS
NIGMS
$2,115,491
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Probing sex differences in myocardial fibrosis at multiple length scales using biomaterials
1TfDP2ActfHL173948Projectf01YearfUNIVERSITY OF CALIFORNIA, SAN DIEGO2023NHLBI
OD
$1,422,000
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Developing long-term neuro-behavioral recording and real-time processing platforms for naturally behaving animals
4TfDP2ActfMH129986Projectf02YearfUNIVERSITY OF CALIFORNIA LOS ANGELES2024NIMH
NIMH
$903,288
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Leveraging HCV Phylogenetic Networks to Prevent HIV and Other Blood Borne Infections Among People Who Inject Drugs
1TfDP2ActfDA053730Projectf01YearfALBERT EINSTEIN COLLEGE OF MEDICINE2021NIDA
NIDA
$2,520,000
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A Novel Semi-autonomous Surgeon-in-the-loop in situ Robotic Bioprinting System for Functional and Cosmetic Restoration of Volumetric Muscle Loss Injuries
1TfDP2ActfAR082471Projectf01YearfUNIVERSITY OF TEXAS AT AUSTIN2022NIAMS
OD
$1,354,107
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Harnessing sensory food circuits to influence feeding behavior
4TfDP2ActfAT011965Projectf02YearfMONELL CHEMICAL SENSES CENTER2024NCCIH
OD
$981,000
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Hormonal Response to Infant Caregiving: A Novel Strategy to Break the Opioid Relapse Cycle during the Postpartum Period
1TfDP2ActfHD105541Projectf01YearfUNIVERSITY OF ARIZONA2020NICHD
OD
$2,302,500
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Maternal immune activation remodeling of offspring glycosaminoglycan sulfation patterns during neurodevelopment
5TfDP2ActfAI171150Projectf02YearfUNIVERSITY OF WASHINGTON2024NIAID
NIAID
$507,211
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Maternal immune activation remodeling of offspring glycosaminoglycan sulfation patterns during neurodevelopment
3TfDP2ActfAI171150Projectf02S1YearfUNIVERSITY OF WASHINGTON2024NIAID
NIAID
$69,428
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HIV and Cocaine Drive Bone-Marrow Blood (BMB) Barrier Dysfunction and Altered Hematopoietic Stem Cell (HSC) Differentiation Leading to Cardiovascular Disease
7TfDP2ActfDA056172Projectf02YearfUNIVERSITY OF FLORIDA2022NIDA
NIDA
$1,699,969
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Implantable Nanophotonic Sensors for in Vivo Immunoresponse
1TfDP2ActfDE030713Projectf01YearfUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2020NIDCR
NIDCR
OD
$1,922,500
$500,000
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Taking Our Shot: Extended-Release Naltrexone as Opioid Overdose Pre-Exposure Prophylaxis (PrEP) in People Using Stimulants Living With or At Risk of HIV
1TfDP2ActfDA060600Projectf01YearfUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2024NIDA
NIDA
$2,460,000
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Uncovering brain-wide molecular determinants of individual memory performance across lifespan
1TfDP2ActfNS132372Projectf01YearfBAYLOR COLLEGE OF MEDICINE2022NINDS
OD
$1,427,700
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A Paradigm Shift in Health Behavior Change: Understanding When and How Social Comparison Supports Healthy Behavior
1TfDP2ActfHL173857Projectf01YearfROWAN UNIVERSITY2023NHLBI
OD
$1,336,496
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Using a specialized behavior to study the neural mechanisms of episodic memory
1TfDP2ActfAG071918Projectf01YearfCOLUMBIA UNIVERSITY HEALTH SCIENCES2020NIA
OD
$2,430,000
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Decoding the fundamental principles of autonomous clocks: mechanism, design and function
1TfDP2ActfGM154328Projectf01YearfUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2023NIGMS
OD
$1,453,500
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A systems-level approach to decipher the protein interactome.
4TfDP2ActfGM146246Projectf02YearfUNIVERSITY OF CALIFORNIA LOS ANGELES2024NIGMS
OD
$921,934
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The facts of the matter: decoding the molecular properties of brain white matter using cell-type-specific quantitative proteomics
1TfDP2ActfNS136873Projectf01YearfUNIV OF NORTH CAROLINA CHAPEL HILL2023NINDS
OD
$1,377,516
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The Multisensory Ontogeny of Social Behavior
1TfDP2ActfHD118871Projectf01YearfUNIVERSITY OF CALIFORNIA, SAN DIEGO2024NICHD
OD
$1,340,637
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Mapping and Therapeutic Hijacking of Lysosomal Transport
1TfDP2ActfGM154016Projectf01YearfSTANFORD UNIVERSITY2023NIGMS
NIGMS
$1,385,226
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Developing next-generation nanodiscs for the study and modulation of membrane proteins
7TfDP2ActfGM140920Projectf03YearfUNIVERSITY OF VIRGINIA2020NIGMS
NIGMS
$755,071
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Development of a novel community-based high-performance surveillance network for drug use
7TfDP2ActfDA051864Projectf02YearfUNIVERSITY OF COLORADO DENVER2020NIDA
NIDA
$2,263,722
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Bioengineering Tools to Resolve and Manipulate Neuroimmune Signaling
1TfDP2ActfMH136493Projectf01YearfARIZONA STATE UNIVERSITY-TEMPE CAMPUS2023NIMH
NIMH
$1,336,458
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Profiling Transcriptional Heterogeneity in Microbial Cells at Single Cell resolution and High-throughput using Droplet Microfluidics
1TfDP2ActfAI158157Projectf01YearfUNIVERSITY OF CHICAGO2020NIAID
OD
$2,430,000
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Investigating the role of liquid-liquid phase separation in the interaction between Mycobacterium tuberculosis and macrophages
5TfDP2ActfAI154429Projectf04YearfRUTGERS BIOMEDICAL AND HEALTH SCIENCES2024NIAID
NIAID
$466,072
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Uncovering cellular and molecular adaptations for whole-organism rejuvenation
1TfDP2ActfAG093210Projectf01YearfBAYLOR COLLEGE OF MEDICINE2024NIA
OD
$1,359,000
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Immune regulation of tissue iron in health and disease
5TfDP2ActfAI154440Projectf04YearfRUTGERS BIOMEDICAL AND HEALTH SCIENCES2024NIAID
NIAID
$448,701
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Towards a Smart Bionic Eye: AI-Powered Artificial Vision for the Treatment of Incurable Blindness
1TfDP2ActfLM014268Projectf01YearfUNIVERSITY OF CALIFORNIA SANTA BARBARA2022NLM
OD
$1,250,136
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Evolution of heat tolerance and drug resistance in Cryptococcus
1TfDP2ActfAI184725Projectf01YearfUNIVERSITY OF GEORGIA2024NIAID
NIAID
$443,944
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Repertoire-scale T cell antigen identification via peptide-MHC lentivirus display
1TfDP2ActfAI158126Projectf01YearfMASSACHUSETTS INSTITUTE OF TECHNOLOGY2020NIAID
OD
$2,316,417
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Deciphering long-term virus evolution through the reconstruction of past viral genomes
5TfDP2ActfAI177896Projectf02YearfFRED HUTCHINSON CANCER CENTER2024NIAID
NIAID
$508,951
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Synthetic metabolism to armor and enhance a new class of cell therapies
1TfDP2ActfCA280622Projectf01YearfGEORGIA INSTITUTE OF TECHNOLOGY2022NCI
OD
$1,356,578
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Shifting Suicide Prevention Paradigms: Looking Beyond Clinical Settings
4TfDP2ActfMH129967Projectf02YearfUNIVERSITY OF SOUTHERN CALIFORNIA2024NIMH
NIMH
$917,998
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Uncovering the role of extracellular condensates as triggers of neuroinflammation
1TfDP2ActfNS142714Projectf01YearfBAYLOR COLLEGE OF MEDICINE2024NINDS
OD
$1,440,000
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Simulating Ancestrally Unbiased Tumor Evolution To Interrogate Drug Resistance
1TfDP2ActfCA290244Projectf01YearfUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2023NCI
OD
$1,453,500
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Host-Dependent Mechanisms that Guide the Longitudinal Dynamic of Sites of SIV Integration
1TfDP2ActfAI184811Projectf01YearfBETH ISRAEL DEACONESS MEDICAL CENTER2024NIAID
NIAID
$500,475
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Crossing scales to predict and prevent bat virus zoonoses in a Madagascar ecosystem
3TfDP2ActfAI171120Projectf03S1YearfUNIVERSITY OF CHICAGO2024NIAID
NIAID
$91,090
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Crossing scales to predict and prevent bat virus zoonoses in a Madagascar ecosystem
3TfDP2ActfAI171120Projectf03S2YearfUNIVERSITY OF CHICAGO2025NIAID
NIAID
$50,856
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Crossing scales to predict and prevent bat virus zoonoses in a Madagascar ecosystem
5TfDP2ActfAI171120Projectf03YearfUNIVERSITY OF CHICAGO2024NIAID
NIAID
$451,808
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The Circadian Clock Coordinates Animal and Microbial Metabolism
1TfDP2ActfDK143367Projectf01YearfPRINCETON UNIVERSITY2024NIDDK
OD
$1,457,999
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Off the beaten path(way): Spatiotemporal investigation of protein assemblies controlling mitochondrial metabolism
4TfDP2ActfGM146255Projectf02YearfVANDERBILT UNIVERSITY2024NIGMS
OD
$946,320
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Acceptance of non-self: Decoding intestinal immune tolerance during early life
5TfDP2ActfAI171116Projectf03YearfSLOAN-KETTERING INST CAN RESEARCH2024NIAID
NIAID
$531,000
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Dissecting the thermosensory biology of soil-transmitted parasitic nematodes
1TfDP2ActfAI184544Projectf01YearfUNIVERSITY OF WASHINGTON2024NIAID
NIAID
$455,140
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The inactive X: discovering sex genes that influence female vulnerability to Alzheimer's disease
1TfDP2ActfAG082342Projectf01YearfMASSACHUSETTS GENERAL HOSPITAL2022NIA
NIA
$1,512,000
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IDENTIFYING MICROBIAL MECHANISMS THAT REGULATE ANIMAL INSULIN SIGNALING
1TfDP2ActfDK139569Projectf01YearfVAN ANDEL RESEARCH INSTITUTE2023NIDDK
OD
$1,710,000
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Novel extremophile-inspired radioprotectants
1TfDP2ActfCA301081Projectf01YearfUNIVERSITY OF IOWA2024NCI
OD
$1,354,009
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