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Fiscal Year: Active ProjectsActivity Code: k99IC Code: ca

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TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
Elucidating the role of hepatic ketogenesis in pancreatic cancer cachexia and recovery
5TfK99ActfCA286709Projectf02Yearf
ARNESON-WISSINK, PAIGE C Principal Investigator(s)/ Project Leader(s)
OREGON HEALTH & SCIENCE UNIVERSITY2025NCI
NCI
$118,041
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A Virtual, Group-Based, Expressive Writing Intervention for Survivors of Adolescent and Young Adult Cancer
1TfK99ActfCA293336Projectf01Yearf
CHOI, EUNJU Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF TX MD ANDERSON CAN CTR2024NCI
NCI
$161,432
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Dissecting the Role of Germline Genetics in RAS-Driven Cancers
5TfK99ActfCA286805Projectf02Yearf
COLLINS, RYAN LEWIS Principal Investigator(s)/ Project Leader(s)
DANA-FARBER CANCER INST2025NCI
NCI
$163,728
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Dissecting the contribution of mis-splicing in cancer phenotypes through multi-omic single-cell approaches
1TfK99ActfCA297005Projectf01Yearf
CORTES LOPEZ, MARIELA Principal Investigator(s)/ Project Leader(s)
WEILL MEDICAL COLL OF CORNELL UNIV2025NCI
NCI
$122,032
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Targeting Perp in PDAC tumor and cancer cachexia
1TfK99ActfCA283277Projectf01A1Yearf
DASGUPTA, ANEESHA Principal Investigator(s)/ Project Leader(s)
INDIANA UNIVERSITY INDIANAPOLIS2024NCI
NCI
$131,072
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Assessing how multilevel factors shape disparities in cancer screening
5TfK99ActfCA277552Projectf02Yearf
DEL VECCHIO, NATALIE Principal Investigator(s)/ Project Leader(s)
FRED HUTCHINSON CANCER CENTER2024NCI
NCI
$209,250
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Translation Rewiring Underlines Drug Resistance to Lethal Targeted Ribosome Biogenesis Therapeutics in Cancer
5TfK99ActfCA279786Projectf02Yearf
FAN, WENJUN Principal Investigator(s)/ Project Leader(s)
JOHNS HOPKINS UNIVERSITY2025NCI
NCI
$109,705
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Mechanisms and vulnerabilities of ERG-driven luminal fate in prostate cancer
5TfK99ActfCA276888Projectf02Yearf
FENG, WEIRAN Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2024NCI
NCI
$173,016
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Harnessing neutrophils to improve the efficacy of immune checkpoint inhibitors in breast cancer
5TfK99ActfCA279899Projectf02Yearf
GAO, YANG Principal Investigator(s)/ Project Leader(s)
BAYLOR COLLEGE OF MEDICINE2024NCI
NCI
$120,466
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Elucidating Thiol Reductive Stress in Lung Cancer Growth and Metastasis
1TfK99ActfCA296772Projectf01Yearf
GE, MAOLIN Principal Investigator(s)/ Project Leader(s)
MASSACHUSETTS GENERAL HOSPITAL2025NCI
NCI
$140,130
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Single cell chromatin profiling to study epigenetic alterations of ovarian tumors
5TfK99ActfCA273420Projectf02Yearf
GOPALAN, SNEHA Principal Investigator(s)/ Project Leader(s)
UNIV OF MASSACHUSETTS MED SCH WORCESTER2023NCI
NCI
$124,681
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Dietary Control of the Pro-Metastatic Niche in Colorectal Cancer
5TfK99ActfCA287057Projectf02Yearf
GOSWAMI, SWAGATA Principal Investigator(s)/ Project Leader(s)
MASSACHUSETTS INSTITUTE OF TECHNOLOGY2025NCI
NCI
$142,301
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Programmable biohybrid system for cancer therapy
5TfK99ActfCA283259Projectf02Yearf
HAHN, JAESEUNG Principal Investigator(s)/ Project Leader(s)
COLUMBIA UNIVERSITY HEALTH SCIENCES2025NCI
NCI
$172,044
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Influence of Social Determinants of Health and Epigenomics on Psychological Symptom Cluster Severity
5TfK99ActfCA286967Projectf02Yearf
HARRIS, CAROLYN STIGGE Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF PITTSBURGH AT PITTSBURGH2025NCI
NCI
$161,556
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Integration of multi-omics to predict and evaluate response during optimization of a nutrition intervention for cancer survivors with overweight and obesity
5TfK99ActfCA287061Projectf02Yearf
HILL, EMILY B. Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF COLORADO DENVER2025NCI
NCI
$116,924
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Defining kinase interaction pathways to enhance anti-cancer efficacy and minimize associated morbidities of kinase inhibitor drugs.
5TfK99ActfCA279895Projectf02Yearf
HNATIUK HNATIUK, ANNA PAVLOVNA Principal Investigator(s)/ Project Leader(s)
STANFORD UNIVERSITY2024NCI
NCI
$153,954
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The role of the novel interface cell state in melanoma invasion
5TfK99ActfCA266931Projectf02Yearf
HUNTER, MIRANDA VICTORIA Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2024NCI
NCI
$173,016
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LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Protocol for Patients Living with Metastatic Lung Cancer
1TfK99ActfCA286959Projectf01Yearf
HYLAND, KELLY ALEXANDRA Principal Investigator(s)/ Project Leader(s)
DUKE UNIVERSITY2024NCI
NCI
$102,249
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The role of AHR in modulatingimmunotherapy response and adverse events in bladder cancer
5TfK99ActfCA286742Projectf02Yearf
JANG, HYO SIK Principal Investigator(s)/ Project Leader(s)
VAN ANDEL RESEARCH INSTITUTE2025NCI
NCI
$153,160
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Metabolically Reprogramming Hepatic Macrophages to Conquer Immune Desert Tumors
1TfK99ActfCA297030Projectf01Yearf
JI, LIANGLIANG Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2025NCI
NCI
$145,336
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Quantitative modeling of extrachromosomal DNA (ecDNA) evolution in tumors
5TfK99ActfCA286968Projectf02Yearf
JONES, MATTHEW GREGORY Principal Investigator(s)/ Project Leader(s)
STANFORD UNIVERSITY2025NCI
NCI
$167,508
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Developing a communication support intervention for cancer caregivers in emerging and young adulthood
1TfK99ActfCA279651Projectf01A1Yearf
KASTRINOS, AMANDA Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2024NCI
NCI
$135,224
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Quantitative characterization of tumor heterogeneity using habitat imaging for the prediction of patient outcome in triple negative breast cancer
1TfK99ActfCA293004Projectf01Yearf
KAZEROUNI, ANUM SYED Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF WASHINGTON2024NCI
NCI
$101,458
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Esophageal squamous cell cancer initiation and immune landscape remodeling
1TfK99ActfCA286761Projectf01A1Yearf
KO, KYUNG PIL Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF TX MD ANDERSON CAN CTR2024NCI
NCI
$128,936
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Functional Landscape of Glycosylation in Skin Cancer
5TfK99ActfCA277591Projectf02Yearf
KUDELKA, MATTHEW ROBERT Principal Investigator(s)/ Project Leader(s)
ROCKEFELLER UNIVERSITY2024NCI
NCI
$178,427
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IL-27 functions as a novel signal 3 cytokine and promotes cytotoxic T cell responses to tumors
1TfK99ActfCA290077Projectf01A1Yearf
LAFLEUR, MARTIN Principal Investigator(s)/ Project Leader(s)
HARVARD MEDICAL SCHOOL2025NCI
NCI
$163,296
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Identifying and examining the effects of source and presentation on responses to electronic cigarette public education messages in young adult vapers and non-vapers
5TfK99ActfCA281094Projectf02Yearf
LEE, DONGHEE NICOLE Principal Investigator(s)/ Project Leader(s)
UNIV OF MASSACHUSETTS MED SCH WORCESTER2025NCI
OD
$137,562
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Targeting the evolving immunopeptidome of metastatic colorectal cancer
1TfK99ActfCA297011Projectf01Yearf
LEE, JAEYOP Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2025NCI
NCI
$154,642
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Large-scale artificial intelligence using radiomics, deep learning, and physics-based generative modeling to improve clinical outcomes in nuclear medicine
5TfK99ActfCA287045Projectf02Yearf
LEUNG, KEVIN HO-YIN Principal Investigator(s)/ Project Leader(s)
JOHNS HOPKINS UNIVERSITY2025NCI
NCI
$170,100
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Discovering and Characterizing Druggable Cysteines in Cancer Dependency Proteins
1TfK99ActfCA290143Projectf01Yearf
LI, HAOXIN Principal Investigator(s)/ Project Leader(s)
SCRIPPS RESEARCH INSTITUTE, THE2024NCI
NCI
$165,780
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SERPINE family genes in rhabdoid tumorigenesis
1TfK99ActfCA297000Projectf01Yearf
LI, YIZE Principal Investigator(s)/ Project Leader(s)
WASHINGTON UNIVERSITY2025NCI
NCI
$113,372
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Targeting mitochondrial vulnerabilities to drive intrinsic melanoma immunogenicity
1TfK99ActfCA283154Projectf01A1Yearf
LIANG, JIAXIN Principal Investigator(s)/ Project Leader(s)
DANA-FARBER CANCER INST2024NCI
NCI
$128,798
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Defining novel mechanisms of microbiota in regulating anti-tumor responses
1TfK99ActfCA290052Projectf01Yearf
LYU, MENGZE Principal Investigator(s)/ Project Leader(s)
WEILL MEDICAL COLL OF CORNELL UNIV2024NCI
NCI
$138,240
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Paving the way for bystander T cell immunotherapies
1TfK99ActfCA296729Projectf01Yearf
MAURICE, NICHOLAS JOSEPH Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF MINNESOTA2025NCI
NCI
$113,937
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The Gut Microbial and Dietary Origins of Cancer Treatment-Related CognitiveImpairment
1TfK99ActfCA293168Projectf01Yearf
MCLEOD, ANDREW P Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF ILLINOIS AT CHICAGO2024NCI
NCI
$150,701
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Investigating the interplay between senescence and T cell immunity
5TfK99ActfCA279782Projectf02Yearf
MEZZADRA, RICCARDO Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2024NCI
NCI
$143,275
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Functional and Pharmacologic Investigation of the NUP98 Fusion Oncoprotein Interactome
5TfK99ActfCA283256Projectf02Yearf
MICHMERHUIZEN, NICOLE Principal Investigator(s)/ Project Leader(s)
ST. JUDE CHILDREN'S RESEARCH HOSPITAL2024NCI
NCI
$140,959
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Dissecting spatiotemporal heterogeneity of glioblastoma evolution under therapy
5TfK99ActfCA286730Projectf02Yearf
MIGLIOZZI, SIMONA Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF MIAMI SCHOOL OF MEDICINE2025NCI
NCI
$113,995
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Genetic dependencies in KIAA1549-BRAF rearranged pediatric low-grade gliomas
1TfK99ActfCA290163Projectf01A1Yearf
MISEK, SEAN ALEXANDER Principal Investigator(s)/ Project Leader(s)
BROAD INSTITUTE, INC.2025NCI
NCI
$143,788
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Role of BCL11B in lineage ambiguous leukemia
5TfK99ActfCA279756Projectf02Yearf
MONTEFIORI, LINDSEY Principal Investigator(s)/ Project Leader(s)
ST. JUDE CHILDREN'S RESEARCH HOSPITAL2024NCI
NCI
$136,176
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The role of oral microbiota in metastatic brain tumors
1TfK99ActfCA296780Projectf01Yearf
MORAD, GOLNAZ Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF TX MD ANDERSON CAN CTR2025NCI
NCI
$112,026
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Targeting Cancer at the Protein-Membrane Interface
5TfK99ActfCA277358Projectf02Yearf
MORSTEIN, JOHANNES Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO2024NCI
NCI
$163,080
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Recognition of ribonucleoprotein (RNP) substrate by the poly(A) exosome targeting (PAXT) complex
5TfK99ActfCA267555Projectf02Yearf
PARK, MI SEUL Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2023NCI
NCI
$119,176
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Developing and Validating Prognostic Models for Black women with Endometrial Cancer following Hysterectomy
1TfK99ActfCA297013Projectf01Yearf
PEERI, NOAH CHARLES Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2025NCI
NCI
$132,825
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Targeting Pancreatic Cancer Senescence with ImmunoPET
1TfK99ActfCA276804Projectf01A1Yearf
PRATT, EDWIN CHARLES Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2024NCI
NCI
$148,282
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Refining Cognitive Behavioral Therapy for Insomnia in Lung Cancer Survivors: Enhancing Feasibility, Acceptability, and Symptom Management
1TfK99ActfCA297014Projectf01Yearf
PRICE, SARAH NEWMEYER Principal Investigator(s)/ Project Leader(s)
WAKE FOREST UNIVERSITY HEALTH SCIENCES2025NCI
NCI
$112,484
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The role of Gasdermin D in the bone marrow microenvironment during clonal hematopoiesis progression
1TfK99ActfCA289959Projectf01A1Yearf
REN, KEHAN Principal Investigator(s)/ Project Leader(s)
NORTHWESTERN UNIVERSITY AT CHICAGO2025NCI
NCI
$123,409
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Learning about the effectiveness of lung cancer screening in real-world target populations
5TfK99ActfCA287059Projectf02Yearf
ROBERTSON, SARAH E Principal Investigator(s)/ Project Leader(s)
HARVARD SCHOOL OF PUBLIC HEALTH2025NCI
NCI
$128,773
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A multi-omics approach to evaluate the role of chronic inflammation in breast cancer development
5TfK99ActfCA286891Projectf02Yearf
ROMANOS-NANCLARES, ANDREA Principal Investigator(s)/ Project Leader(s)
BRIGHAM AND WOMEN'S HOSPITAL2025NCI
NCI
$164,570
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Molecular dissection of extrachromosomal DNA formation, development, and evolution
5TfK99ActfCA279512Projectf02Yearf
ROSE, JOHN CHRISTOPHER Principal Investigator(s)/ Project Leader(s)
STANFORD UNIVERSITY2024NCI
NCI
$126,358
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