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7 Projects
Fiscal Year: Active ProjectsPrincipal Investigator (PI): 6603238

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TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome
3TfR01ActfDA050545Projectf05S1Yearf
BUCH, SHILPA J. Principal Investigator(s)/ Project Leader(s)
GUO, MINGLEI Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF NEBRASKA MEDICAL CENTER2023NIDA
NIDA
$383,750
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Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome
5TfR01ActfDA050545Projectf05Yearf
BUCH, SHILPA J. Principal Investigator(s)/ Project Leader(s)
GUO, MINGLEI Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF NEBRASKA MEDICAL CENTER2023NIDA
NIDA
$514,688
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Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine
5TfR01ActfDA047156Projectf05Yearf
BUCH, SHILPA J. Principal Investigator(s)/ Project Leader(s)
GUO, MINGLEI Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF NEBRASKA MEDICAL CENTER2022NIDA
NIDA
$362,188
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HIV Tat and Opiate-mediated aberrations in glial-neuronal crosstalk: Implications for the role of extracellular RNA in HAND
1TfR01ActfDA060755Projectf01A1Yearf
BUCH, SHILPA J. Principal Investigator(s)/ Project Leader(s)
SIL, SUSMITA Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF NEBRASKA MEDICAL CENTER2024NIDA
NIDA
$469,340
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Title: Pharmacokinetic, pharmacodynamic , and toxicological interactions among Opioids and Cabotegravir
5TfR01ActfDA057145Projectf03Yearf
EL-HAGE, NAZIRA Principal Investigator(s)/ Project Leader(s)
BUCH, SHILPA J. Principal Investigator(s)/ Project Leader(s)
FLETCHER, COURTNEY V Principal Investigator(s)/ Project Leader(s)
FLORIDA INTERNATIONAL UNIVERSITY2024NIDA
NIDA
$356,454
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Uncovering HIV/opioid effects in the brain at the single cell level: transcription, chromatin accessibility, and reservoir analysis in the SIV/cART/morphine/rhesus monkey model
5TfU01ActfDA053624Projectf04Yearf
FOX, HOWARD S Principal Investigator(s)/ Project Leader(s)
BUCH, SHILPA J. Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF NEBRASKA MEDICAL CENTER2024NIDA
NIDA
$1,579,167
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Single cell determinants of brain in the context of viral persistence in SIV/cART/cocaine non-human primates
5TfU01ActfDA058402Projectf03Yearf
RANA, TARIQ M Principal Investigator(s)/ Project Leader(s)
BUCH, SHILPA J. Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF CALIFORNIA, SAN DIEGO2025NIDA
NIDA
$2,220,675
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