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Fiscal Year: Active ProjectsActivity Code: f99IC Code: ca

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TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
The Role of Guanine Exchange Factors in Pancreatic Ductal Adenocarcinoma (PDAC)
1TfF99ActfCA294132Projectf01Yearf
BANNOURA, SAHAR Principal Investigator(s)/ Project Leader(s)
WAYNE STATE UNIVERSITY2024NCI
NCI
$50,474
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The Role of Guanine Exchange Factors in Pancreatic Ductal Adenocarcinoma (PDAC)
3TfF99ActfCA294132Projectf01S1Yearf
BANNOURA, SAHAR Principal Investigator(s)/ Project Leader(s)
WAYNE STATE UNIVERSITY2025NCI
NCI
$3,000
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Mapping p53 dynamics to cell-fate outcomes in reprogramming and oncogenesis
5TfF99ActfCA284280Projectf02Yearf
BEITZ, ADAM MATTHEW Principal Investigator(s)/ Project Leader(s)
MASSACHUSETTS INSTITUTE OF TECHNOLOGY2024NCI
NCI
$48,974
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Comparing post-test genetic counseling with and without pre-test counseling: The evolving landscape for optimizing cancer care
1TfF99ActfCA294165Projectf01Yearf
BROADBRIDGE, ELIZABETH Principal Investigator(s)/ Project Leader(s)
RUTGERS, THE STATE UNIV OF N.J.2024NCI
NCI
$38,154
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Microbiome-Mitochondrial Interactions Driving Cancer-Induced Cachexia in the Obese State
1TfF99ActfCA294251Projectf01Yearf
CARDACI, THOMAS Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA2024NCI
NCI
$40,199
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Identifying and Targeting Drivers of Impaired Translation in Tumor-infiltrating CD8+ T-cells.
1TfF99ActfCA294267Projectf01Yearf
CHEN, YAN-TING Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2024NCI
NCI
$50,474
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Identifying and Targeting Drivers of Impaired Translation in Tumor-infiltrating CD8+ T-cells.
3TfF99ActfCA294267Projectf01S1Yearf
CHEN, YAN-TING Principal Investigator(s)/ Project Leader(s)
SLOAN-KETTERING INST CAN RESEARCH2025NCI
NCI
$3,000
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Impact of neurofibromin on ER-alpha and nuclear speck post-transcriptional gene regulation
5TfF99ActfCA284282Projectf02Yearf
DISCHINGER, PATRICK Principal Investigator(s)/ Project Leader(s)
VAN ANDEL RESEARCH INSTITUTE2024NCI
NCI
$47,974
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Impact of neurofibromin on ER-alpha and nuclear speck post-transcriptional gene regulation
3TfF99ActfCA284282Projectf02S1Yearf
DISCHINGER, PATRICK Principal Investigator(s)/ Project Leader(s)
VAN ANDEL RESEARCH INSTITUTE2025NCI
NCI
$3,000
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Understanding expression and signaling of sex hormone receptors in brain cancers
1TfF99ActfCA294312Projectf01Yearf
DWYER CADY, MARTHA ADDISON Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO2024NCI
NCI
$48,717
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Targeting chemotherapy resistant high grade serous ovarian cancer
5TfF99ActfCA284284Projectf02Yearf
EBRAHIMI, BEHNAM Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF TEXAS HLTH SCIENCE CENTER2024NCI
NCI
$36,300
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Real Time Metabolic Imaging to Interrogate Early Detection and Prevention of Pancreatic Cancer
5TfF99ActfCA284365Projectf02Yearf
ENRIQUEZ, JOSE S Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF TX MD ANDERSON CAN CTR2024NCI
NCI
$36,960
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Immune Regulation of Dormancy at the Metastatic Site
5TfF99ActfCA284292Projectf02Yearf
HAN, XIAO Principal Investigator(s)/ Project Leader(s)
STATE UNIVERSITY NEW YORK STONY BROOK2024NCI
NCI
$48,974
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Administrative Supplement: Immune Regulation of Dormancy at the Metastatic Site
3TfF99ActfCA284292Projectf02S1Yearf
HAN, XIAO Principal Investigator(s)/ Project Leader(s)
STATE UNIVERSITY NEW YORK STONY BROOK2025NCI
NCI
$3,000
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The alterations caused by obese extracellular vesicles on colorectal cancer tumor microenvironment
1TfF99ActfCA294247Projectf01Yearf
HAQUE, PARSA Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF COLORADO DENVER2024NCI
NCI
$39,872
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Determinants of susceptibility to pediatric acute myeloid leukemia
3TfF99ActfCA294248Projectf01S1Yearf
HARMON, LAUREN MARIE Principal Investigator(s)/ Project Leader(s)
VAN ANDEL RESEARCH INSTITUTE2025NCI
NCI
$3,000
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Determinants of susceptibility to pediatric acute myeloid leukemia
1TfF99ActfCA294248Projectf01Yearf
HARMON, LAUREN MARIE Principal Investigator(s)/ Project Leader(s)
VAN ANDEL RESEARCH INSTITUTE2024NCI
NCI
$49,474
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Aging in place for older adults with cancer: The role of physical function and home environment
5TfF99ActfCA284180Projectf02Yearf
JENSEN-BATTAGLIA, MARIELLE Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF ROCHESTER2024NCI
NCI
$48,974
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PD-1 blockade effects on bone strength and metastatic progression
1TfF99ActfCA294171Projectf01Yearf
JOSEPH, GWENYTH JEAN Principal Investigator(s)/ Project Leader(s)
VANDERBILT UNIVERSITY2024NCI
NCI
$35,870
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Integrative Deep Learning Models for Multimodal Markers of Cancer Treatment Outcomes
1TfF99ActfCA294169Projectf01Yearf
KREBS, OLIVIA Principal Investigator(s)/ Project Leader(s)
CASE WESTERN RESERVE UNIVERSITY2024NCI
NCI
$39,869
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Dissecting the role of mitochondrial glutathione homeostasis in cancer
5TfF99ActfCA284249Projectf02Yearf
LIU, YUYANG Principal Investigator(s)/ Project Leader(s)
ROCKEFELLER UNIVERSITY2024NCI
NCI
$48,974
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The interface of neurons and cancer
1TfF99ActfCA294269Projectf01Yearf
LUKASIK, KIMBERLY Principal Investigator(s)/ Project Leader(s)
UNIV OF NORTH CAROLINA CHAPEL HILL2024NCI
NCI
$38,079
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The interface of neurons and cancer
3TfF99ActfCA294269Projectf01S1Yearf
LUKASIK, KIMBERLY Principal Investigator(s)/ Project Leader(s)
UNIV OF NORTH CAROLINA CHAPEL HILL2025NCI
NCI
$3,000
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Metabolic Reprogramming of Myeloid Cells to Enhance Cancer Immunotherapy
1TfF99ActfCA294065Projectf01Yearf
MORREALE, BRIAN GEORGE Principal Investigator(s)/ Project Leader(s)
ROSWELL PARK CANCER INSTITUTE CORP2024NCI
NCI
$35,292
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Dissecting the intrinsic and extrinsic regulators of prostate cancer dormancy in the bonemicroenvironment.
5TfF99ActfCA284258Projectf02Yearf
NASR, MOSTAFA M. Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF SOUTH FLORIDA2024NCI
NCI
$40,973
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Dissecting the genetic basis of cancer immune evasion in squamous cell carcinoma
1TfF99ActfCA294257Projectf01Yearf
NICHOLSON, BENJAMIN Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF CHICAGO2024NCI
NCI
$50,474
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Human papillomavirus mRNA detection for assessing cervical cancer risk in resource-limited settings
1TfF99ActfCA294262Projectf01Yearf
NOVAK, EMILIE NEWSHAM Principal Investigator(s)/ Project Leader(s)
RICE UNIVERSITY2024NCI
NCI
$50,474
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Harnessing Extracellular Vesicles to Overcome Radiation Resistance in Pediatric Diffuse Midline Glioma
1TfF99ActfCA294265Projectf01Yearf
OZA, VIRAL Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF KENTUCKY2024NCI
NCI
$35,602
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Fibroblasts in the establishment of the liver pre-metastatic niche
5TfF99ActfCA284357Projectf02Yearf
OZAKI, MICHELLE KAYOKO Principal Investigator(s)/ Project Leader(s)
OREGON HEALTH & SCIENCE UNIVERSITY2024NCI
NCI
$48,974
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Resolving epigenetic determinants of cellular plasticity programs in non-small cell lung cancer
1TfF99ActfCA294252Projectf01Yearf
PATEL, AYUSHI Principal Investigator(s)/ Project Leader(s)
NEW YORK UNIVERSITY SCHOOL OF MEDICINE2024NCI
NCI
$43,550
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Tumor-cell intrinsic and extrinsic determinants of drug resistance and metastasis
3TfF99ActfCA294241Projectf01S1Yearf
PRIMEAUX, MARK Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF NEBRASKA MEDICAL CENTER2025NCI
NCI
$3,000
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Tumor-cell intrinsic and extrinsic determinants of drug resistance and metastasis
1TfF99ActfCA294241Projectf01Yearf
PRIMEAUX, MARK Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF NEBRASKA MEDICAL CENTER2024NCI
NCI
$38,693
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p27pTpT drives cancer-promoting inflammation and shapes the tumor microenvironment (TME) toward a more tumor-permissive state in vivo
3TfF99ActfCA284295Projectf02S1Yearf
RAZAVIPOUR, SEYEDEHFATEMEH Principal Investigator(s)/ Project Leader(s)
GEORGETOWN UNIVERSITY2025NCI
NCI
$3,000
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p27pTpT drives cancer-promoting inflammation and shapes the tumor microenvironment (TME) toward a more tumor-permissive state in vivo
5TfF99ActfCA284295Projectf02Yearf
RAZAVIPOUR, SEYEDEHFATEMEH Principal Investigator(s)/ Project Leader(s)
GEORGETOWN UNIVERSITY2024NCI
NCI
$36,274
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Investigating the Microenvironmental Dysregulation and Polypharmacy Impact during Acute Myeloid Leukemia in an in vitro model of the human bone marrow and in vivo models.
1TfF99ActfCA294129Projectf01Yearf
SHARIPOL, AZMEER Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF ROCHESTER2024NCI
NCI
$39,957
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Investigating the molecular signatures and pathways indicative of air pollution toxicity in lung carcinogenesis using single- and multi-omics analyses of genomics, proteomics, and metabolomics
1TfF99ActfCA294242Projectf01Yearf
TANG, ZIYIN Principal Investigator(s)/ Project Leader(s)
EMORY UNIVERSITY2024NCI
NCI
$50,474
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An In-depth Examination of Psychological Distress among Black Breast Cancer Survivors
1TfF99ActfCA294259Projectf01Yearf
TARIQ, FARIHA Principal Investigator(s)/ Project Leader(s)
VIRGINIA COMMONWEALTH UNIVERSITY2024NCI
NCI
$50,474
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Mechanisms and In Vivo Efficacy of Synergistic Acid Ceramidase and Bcl-2 Inhibition in Acute Myeloid Leukemia
5TfF99ActfCA284252Projectf02Yearf
UNG, JOHNSON Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF VIRGINIA2024NCI
NCI
$38,061
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Ceramide and Cell Metabolism: Defining the Role of Sphingolipids in Modulating Mitochondrial Bioenergetics of Chronic Lymphocytic Leukemia
1TfF99ActfCA294256Projectf01Yearf
VASS, LUKE REMINGTON Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF VIRGINIA2024NCI
NCI
$39,698
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Data-driven Diagnostics using Multimodal- AI Assisted Approaches for Early Cancer Detection
1TfF99ActfCA294164Projectf01Yearf
VILLARREAL, PAULA Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF TEXAS MED BR GALVESTON2024NCI
NCI
$38,383
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Elucidating the role of mRNA m6A methylation in tumorigenesis
5TfF99ActfCA284279Projectf02Yearf
WILKINSON, EMMA ANNE Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF CHICAGO2024NCI
NCI
$48,974
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Discovery of Novel Therapeutic Strategies for Cancer Immunotherapy
1TfF99ActfCA294168Projectf01Yearf
YANG, XUAN Principal Investigator(s)/ Project Leader(s)
YALE UNIVERSITY2024NCI
NCI
$50,474
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Transcriptome and spatial analyses of tumor environment in addressing colorectal cancer racial and ethnical disparities
5TfF99ActfCA284261Projectf02Yearf
YIN, HANG Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF WASHINGTON2024NCI
NCI
$48,974
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Return-to-work issues in healthcare workers diagnosed with cancer: Investigation and Intervention Development
1TfF99ActfCA294268Projectf01Yearf
YOU, KAI-LIN Principal Investigator(s)/ Project Leader(s)
UNIVERSITY OF PITTSBURGH AT PITTSBURGH2024NCI
NCI
$50,474
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