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366 Projects
Fiscal Year: Active ProjectsAgency/Institute/Center: Nat'l Cancer Institute (NCI)Admin: YesFunding: YesFunding Mechanism: SBIR/STTR, Non-SBIR/STTR Contracts
TActProjectYearSubPrincipal Investigator(s)/ Project Leader(s)OrganizationFiscal YearAdmin ICFunding ICFY Total Cost by ICSimilar Projects
Comparison of convection enhanced delivery systems in a randomized controlled clinical study of recurrent Grade 3-4 glioma patients
1TfR44ActfCA295197Projectf01YearfCREOSALUS, INC.2024NCI
NCI
$857,315
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Ceraxa (Ceramide NanoLiposome) and Vinblastine For the Improved Treatment of Relapsed or Refractory Acute Myeloid Leukemia
5TfR44ActfCA275609Projectf02YearfKEYSTONE NANO, INC.2023NCI
NCI
$999,628
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Comprehensive validation and commercial readiness of SpliceIO, a software platform for neoantigen discovery using RNA-seq data
3TfR44ActfCA265446Projectf02S1YearfENVISAGENICS, INC.2023NCI
NCI
$77,000
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Comprehensive validation and commercial readiness of SpliceIO, a software platform for neoantigen discovery using RNA-seq data
5TfR44ActfCA265446Projectf02YearfENVISAGENICS, INC.2023NCI
NCI
$980,257
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Development of an immunomodulating peptide as a therapy for osteosarcoma in canine and human
5TfR44ActfCA278570Projectf02YearfPHARMAIN CORPORATION2024NCI
NCI
$995,099
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Orphan Non-coding RNA-based Test for Detecting Minimal Residual Disease in Resectable Non-small Cell Lung Cancer
1TfR44ActfCA291369Projectf01A1YearfEXAI BIO, INC.2024NCI
NCI
$1,280,908
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Development of a Novel Immunotherapeutic for Acute Myeloid Leukemia
1TfR44ActfCA285206Projectf01A1YearfCAMBIUM ONCOLOGY LLC2024NCI
NCI
$404,995
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Preventing chemotherapy-related toxicities and infections with a novel phosphorylated triblock copolymer
1TfR41ActfCA287593Projectf01YearfCOVIRA SURGICAL2024NCI
NCI
$400,000
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FY24 SBIR PHASE IITOPIC NO. 423 PROJECT TITLE: "PASSIVE AND ACTIVE AI SCREENING FOR SOCIAL DETERMINANTS OF HEALTH AND INTERVENTIONS TO IMPROVE OUTCOMES IN THE CANCER PATIENT POPULATION".
75N91024C00086-0-9999-1TfPIECES TECHNOLOGIES, INC.2024NCI
NCI
$1,999,994
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Development of a novel small molecule RPN13 inhibitor and therapeutic for advanced ovarian cancer patients
5TfR44ActfCA278176Projectf02YearfUP THERAPEUTICS, INC.2024NCI
NCI
$1,178,998
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Rapid, Multiplexed Biosensor for Non-Invasive Detection of Gene Mutations and Personalization of Therapy in Non-Small Cell Lung Cancer
5TfR44ActfCA240021Projectf03YearfGINER, INC.2023NCI
NCI
$997,685
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Development ofsynthetic heparin to protect liver graft from ischemia reperfusion injury duringtransplantation
6TfR41ActfCA285005Projectf02YearfGLYCO DISCOVERIES, INC2023NCI
NCI
$148,924
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Modex, a cloud-based, centralized health economic model marketplace to reduce costs and enhance equity in cancer
1TfR43ActfCA297808Projectf01YearfARNOLD CONSULTANCY AND TECHNOLOGY, LLC2025NCI
NCI
$357,371
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Development of small molecule therapeutics targeting AR-V7 for prostate cancer
3TfR42ActfCA290913Projectf01S1YearfARMA BIO, INC.2024NCI
NCI
$55,000
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Development of small molecule therapeutics targeting AR-V7 for prostate cancer
1TfR42ActfCA290913Projectf01YearfARMA BIO, INC.2024NCI
NCI
$406,489
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PyroTIMER Technology: Enabling T-Cell Persistence in Immunosuppressive Tumor Microenvironments
1TfR44ActfCA295355Projectf01YearfPYROJAS INC2024NCI
NCI
$748,337
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Targeting pancreatic cancer metastases with Targefrin
1TfR43ActfCA277917Projectf01A1YearfARMIDA LABS, INC.2023NCI
NCI
$400,000
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Targeting pancreatic cancer metastases with Targefrin
3TfR43ActfCA277917Projectf01A1S1YearfARMIDA LABS, INC.2024NCI
NCI
$187,500
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Next Generation Gene-Gun Delivered DNA and RNA Immunotherapeutic Vaccines for Melanoma.
5TfR43ActfCA281585Projectf02YearfORLANCE, INC.2024NCI
NCI
$200,000
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MammoCAT Advanced Full Field Digital Mammography System
5TfR44ActfCA268305Projectf02YearfFISCHER IMAGING, INC.2023NCI
NCI
$979,261
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Sedationless Multi-View High-Resolution Endoscopy
5TfR44ActfCA265758Projectf03YearfOMNISCIENT IMAGING, INC.2023NCI
NCI
$918,003
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Human specific STING agonists for the treatment of cancer
1TfR41ActfCA275637Projectf01A1YearfSTINGINN, LLC2023NCI
NCI
$399,812
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STING Activators as Therapy for Cancer
5TfR42ActfCA250629Projectf03YearfSTINGINN, LLC2023NCI
NCI
$993,879
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Human T Cell Lymphotropic Virus Vaccine Development
9TfR42ActfCA290612Projectf03YearfSTINGINN, LLC2024NCI
NCI
$999,969
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Targeting Macrophages to Treat Soft Tissue Sarcomas
5TfR44ActfCA285036Projectf03YearfRESOLUTE SCIENCE, INC.2025NCI
NCI
$998,212
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Monitoring Immunotherapy Response via Gene Silencing Landscapes in Cell-Free DNA
2TfR44ActfCA285041Projectf02YearfBINARY GENOMICS, INC.2024NCI
NCI
$990,771
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Clinical Translation of Near Infrared Nerve-Specific Fluorophores for Nerve-sparing Prostatectomy
5TfR44ActfCA247639Projectf04YearfTRACE BIOSCIENCES INC2024NCI
NCI
$810,809
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A novel MICA/B based tumor-centric bispecific antibody that enhances NK cell activity in a hostile tumor microenvironment
1TfR43ActfCA287713Projectf01YearfAAKHA BIOLOGICS INC.2024NCI
NCI
$400,000
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TOPIC 464: CLOUD-BASED MULTIMODAL DATA ANALYSIS SOFTWARE FOR THE CANCER RESEARCH DATA COMMONS
75N91024C00080-0-9999-1TfANACONDA, INC2024NCI
NCI
$399,828
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Development of SUMO1 small molecule degraders as the first-in-class anticancerdrugs for metastatic colorectal cancer
5TfR44ActfCA265547Projectf02YearfHB THERAPEUTICS, INC.2023NCI
NCI
$979,536
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HistoneScan™: a multiplex immunoassay for histone epigenetic profiling
5TfR44ActfCA272029Projectf02YearfADEPTRIX CORPORATION2023NCI
NCI
$436,856
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Immunoassay for Measuring Mutation Activated Kinases Across Multiple Cell Signaling Pathways
1TfR43ActfCA291535Projectf01YearfADEPTRIX CORPORATION2024NCI
NCI
$295,230
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CTO1681 to prevent and mitigate cytokine release syndrome in CAR T-cell recipients
1TfR44ActfCA287634Projectf01A1YearfCYTOAGENTS, INC.2024NCI
NCI
$994,859
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Treating non-small cell lung tumors with a novel inhaled dry powder chemotherapeutic formulation
5TfR44ActfCA277898Projectf02YearfQUENCH MEDICAL, INC.2024NCI
NCI
$874,452
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Development of a Universal Assay for Minimal Residual Disease in Acute Myeloid Leukemia using Duplex Sequencing
5TfR44ActfCA233381Projectf06YearfTWINSTRAND BIOSCIENCES, INC.2025NCI
NCI
$1,985,831
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Development and Commercialization of a New Molecularly Targeted Imaging Agent for Multiple Myeloma
5TfR42ActfCA257797Projectf03YearfSARYA, LLC2024NCI
NCI
$974,650
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FY24 SBIR PHASE II RD CONTRACT - TOPIC 442 BOSTON CELL STANDARDS, INC.
75N91024C00087-0-9999-1TfBOSTON CELL STANDARDS INC2024NCI
NCI
$1,995,119
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SBIR TOPIC 434 PHASE II: ULTRA-FAST DOSE RATE (FLASH) RADIATION DETECTORS AND SAFETY SYSTEMSPERIOD OF PERFORMANCE: 16 SEPTEMBER 2024 - 15 SEPTEMBER 2026FIRM FIXED PRICE
75N91024C00091-0-9999-1TfPYRAMID TECHNICAL CONSULTANTS, INC.2024NCI
NCI
$1,980,915
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Computer Guided Microwave Liver Ablation
1TfR44ActfCA287803Projectf01YearfNE SCIENTIFIC, LLC2024NCI
NCI
$603,206
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Clinical testing of Listeria-TT and Gemcitabine in a Phase I clinical trial with PDAC patients
1TfR42ActfCA287679Projectf01YearfLOKI THERAPEUTICS, INC2024NCI
NCI
$294,962
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Biomarker Rich Clinical Trial of an Innovative Antibody Antagonist of TNFR2 in Non-Hodgkin Lymphoma Featuring Cutaneous T Cell Lymphoma (CTCL).
2TfR44ActfCA265510Projectf04YearfBOSTON IMMUNE TECHNOLOGIES AND THERAPEUTICS, INC.2024NCI
NCI
$1,565,481
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An Open-Labeled, Single Arm Phase 2 Efficacy and Safety Study of REM-001 Photodynamic Therapy (PDT) for Treatment of Cutaneous Metastatic Breast Cancer (CMBC)
5TfR44ActfCA281615Projectf02YearfKINTARA THERAPEUTICS, INC.2024NCI
NCI
$745,259
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PHASE I FAST TRACK TOPIC 461 CONFORMABLE SCINTILLATOR ARRAY FOR IN VIVO DOSIMETRY DURING RT
75N91024C00083-0-9999-1TfDOSEOPTICS, LLC2024NCI
NCI
$394,578
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Ultra-fast imaging for the safe delivery of electron FLASH radiation therapy
5TfR44ActfCA268466Projectf03YearfDOSEOPTICS, LLC2023NCI
NCI
$999,998
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SSW Works: A Virtual Learning Environment for Occupational Skin Cancer Prevention
5TfR44ActfCA257778Projectf03YearfKLEIN BUENDEL, INC.2023NCI
NCI
$750,792
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A Novel, Low-Cost, Handheld, 3D Imaging System for Improved Screening of Cervical Neoplasia in Resource Limited Settings
5TfR44ActfCA254586Projectf03YearfPENSIEVISION, INC.2024NCI
NCI
$1,041,955
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Reducing the incidence of febrile neutropenia in cancer patients treated with chemotherapy with PointCheck: a portable non-invasive neutropenia analyzer
2TfR44ActfCA228920Projectf04YearfLEUKO LABS, INC.2024NCI
NCI
$1,702,979
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Pivotal Clinical Study of the TruScore Device for Non-Invasive Skin Cancer Diagnostics
5TfR44ActfCA203038Projectf06YearfVERISKIN, INC.2024NCI
NCI
$742,845
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TOPIC 423 (PHASE II): AN INTEGRATED MULTI-LEVEL DECISION SUPPORT PLATFORM TO ADDRESS PATIENT-CENTERED AND EVIDENCE-BASED SOCIAL DETERMINANTS OF HEALTH AMONG CANCER PATIENTS.
75N91023C00056-0-9999-1TfPISTEVO DECISION LLC2023NCI
NCI
$2,047,174
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Portable, low-cost cryotherapy system that does not require consumable cryogen gas for the treatment of cervical precancerous lesions
2TfR44ActfCA278186Projectf02A1YearfANANYA HEALTH INC2024NCI
NCI
$1,172,978
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