RePORT ⟩ RePORTER

T	Act	Project	Year	Principal Investigator(s)/ Project Leader(s)	Organization	Fiscal Year	Admin IC	Funding IC	FY Total Cost by IC	Similar Projects
Small Molecule Therapeutics for Sickle Cell Anemia
5Tf	R33Actf	HL163743Projectf	03Yearf	ARCHER, DAVID R Principal Investigator(s)/ Project Leader(s)	EMORY UNIVERSITY	2025	NHLBI	NHLBI	$489,554	View View Similar Projects Similar Projectsf
Development of tolerogenic Factor VIII as immunotherapy to prevent inhibitor development in Hemophilia A
5Tf	R61Actf	HL161818Projectf	02Yearf	BALU-IYER, SATHY VENKAT Principal Investigator(s)/ Project Leader(s)	STATE UNIVERSITY OF NEW YORK AT BUFFALO	2024	NHLBI	NHLBI	$545,700	View View Similar Projects Similar Projectsf
Functional assay development for tafazzin enzyme replacement candidate selection
4Tf	R33Actf	HL154137Projectf	03Yearf	CHIN, MICHAEL T Principal Investigator(s)/ Project Leader(s)	TUFTS MEDICAL CENTER	2023	NHLBI	NHLBI	$623,000	View View Similar Projects Similar Projectsf
Lead identification and pre-clinical studies on allosteric inhibitors of coagulation factor XIa
4Tf	R33Actf	HL161813Projectf	03Yearf	DESAI, UMESH RAMANLAL Principal Investigator(s)/ Project Leader(s)	VIRGINIA COMMONWEALTH UNIVERSITY	2024	NHLBI	NHLBI	$489,038	View View Similar Projects Similar Projectsf
Preclinical development of a nuclear-targeting biologic that safely increases stem cell expansion in vivo to accelerate recovery from neutropenia after chemotherapy and bone marrow transplant
5Tf	R33Actf	HL163739Projectf	03Yearf	ELSER, JEREMY A Principal Investigator(s)/ Project Leader(s)	SHIP OF THESEUS, LLC	2024	NHLBI	NHLBI	$213,500	View View Similar Projects Similar Projectsf
Optimization of fibroblast-selective inhibitors of YAP/TAZ as novel therapeutics for Pulmonary Fibrosis
4Tf	R33Actf	HL161804Projectf	03Yearf	HEYNEN-GENEL, SUSANNE Principal Investigator(s)/ Project Leader(s) HAAK, ANDREW JON Principal Investigator(s)/ Project Leader(s)	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	2024	NHLBI	NHLBI	$596,061	View View Similar Projects Similar Projectsf
Development of a first-in-class complement inhibitor for treating complement-mediated hematologic diseases
1Tf	R61Actf	HL171747Projectf	01A1Yearf	LIN, FENG C Principal Investigator(s)/ Project Leader(s)	CLEVELAND CLINIC LERNER COM-CWRU	2024	NHLBI	NHLBI	$563,500	View View Similar Projects Similar Projectsf
Triple Gene Therapy for Ischemic Heart Failure
1Tf	R61Actf	HL177472Projectf	01Yearf	MOHAMED, TAMER M A Principal Investigator(s)/ Project Leader(s) ROSENGART, TODD K Principal Investigator(s)/ Project Leader(s)	BAYLOR COLLEGE OF MEDICINE	2025	NHLBI	NHLBI	$560,000	View View Similar Projects Similar Projectsf
Small Molecule Therapeutic for Heart Failure
5Tf	R61Actf	HL171717Projectf	02Yearf	PRASAD, SATHYAMANGLA V Principal Investigator(s)/ Project Leader(s) JOSYULA, VARA PRASAD VN Principal Investigator(s)/ Project Leader(s)	CLEVELAND CLINIC LERNER COM-CWRU	2025	NHLBI	NHLBI	$499,322	View View Similar Projects Similar Projectsf
Adeno-associated virus-mediated SGPL1 gene therapy as a first-in-class treatment for idiopathic pulmonary fibrosis that acts by reducing sphingosine-1-phosphate and downstream profibrotic signaling
1Tf	R61Actf	HL171786Projectf	01Yearf	SABA, JULIE D Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF CALIFORNIA, SAN FRANCISCO	2024	NHLBI	NHLBI	$565,250	View View Similar Projects Similar Projectsf
Optimizing function-selective ERK1/2 inhibitors for reducing AP-1-mediated airway pathology in asthma.
5Tf	R61Actf	HL168723Projectf	02Yearf	SHAPIRO, PAUL S Principal Investigator(s)/ Project Leader(s) DESHPANDE, DEEPAK A Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF MARYLAND BALTIMORE	2024	NHLBI	NHLBI	$495,069	View View Similar Projects Similar Projectsf
Mitigation of Exaggerated Smooth Muscle Force with Inhibitors of Integrin Alpha2Beta1
4Tf	R33Actf	HL163725Projectf	03Yearf	SUNDARAM, APARNA BALA Principal Investigator(s)/ Project Leader(s) JO, HYUNIL Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF CALIFORNIA, SAN FRANCISCO	2024	NHLBI	NHLBI	$565,171	View View Similar Projects Similar Projectsf
Optimizing ELD607 for Delivery by Inhalation
1Tf	R61Actf	HL173911Projectf	01Yearf	TARRAN, ROBERT Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF KANSAS MEDICAL CENTER	2024	NHLBI	NHLBI	$542,500	View View Similar Projects Similar Projectsf
P7C3 based small molecule for Heart failure treatment
1Tf	R61Actf	HL170457Projectf	01A1Yearf	TIPPARAJU, SRINIVAS M. Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF SOUTH FLORIDA	2024	NHLBI	NHLBI	$517,475	View View Similar Projects Similar Projectsf
Novel Gene Therapy for Critical Limb Ischemia and Limb Salvage in Vascular Occlusive Disease
5Tf	R33Actf	HL156152Projectf	03Yearf	VELAZQUEZ, OMAIDA C Principal Investigator(s)/ Project Leader(s) LIU, ZHAO-JUN Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF MIAMI SCHOOL OF MEDICINE	2024	NHLBI	NHLBI	$526,505	View View Similar Projects Similar Projectsf
Novel Gene Therapy for Critical Limb Ischemia and Limb Salvage in Vascular Occlusive Disease
3Tf	R33Actf	HL156152Projectf	03S1Yearf	VELAZQUEZ, OMAIDA C Principal Investigator(s)/ Project Leader(s) LIU, ZHAO-JUN Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF MIAMI SCHOOL OF MEDICINE	2024	NHLBI	NHLBI	$76,750	View View Similar Projects Similar Projectsf
Liposomal azithromycin to treat cardiac inflammation
1Tf	R61Actf	HL177474Projectf	01Yearf	VENDITTO, VINCENT JOSEPH Principal Investigator(s)/ Project Leader(s) ABDEL-LATIF, AHMED Principal Investigator(s)/ Project Leader(s) FEOLA, DAVID Principal Investigator(s)/ Project Leader(s)	UNIVERSITY OF KENTUCKY	2025	NHLBI	NHLBI	$542,094	View View Similar Projects Similar Projectsf
Targeting Integrin Signaling in Atherosclerosis
5Tf	R61Actf	HL168737Projectf	02Yearf	WOODSIDE, DARREN G Principal Investigator(s)/ Project Leader(s) BIEDIGER, RONALD J Principal Investigator(s)/ Project Leader(s)	TEXAS HEART INSTITUTE	2024	NHLBI	NHLBI	$556,549	View View Similar Projects Similar Projectsf

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